Ping-an Hu
Central South University
AdipogenesisInternal medicineEndocrinologyCellular differentiationWhite adipose tissueMolecular biologyAdipose tissueChemistryPeroxisome proliferator-activated receptorLipid dropletAdipocyteNeurotransmitterHypothalamusMTT assayEnhancer bindingCell growthNeuropeptide Y receptor
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#1Min Liu (CSU: Central South University)H-Index: 2
#2Hong Liu (CSU: Central South University)H-Index: 1
Last. Ping-an Hu (CSU: Central South University)H-Index: 1
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: Neuropeptide Y (NPY) is an important neurotransmitter in the control of energy metabolism. Several studies have shown that obesity is associated with increased levels of NPY in the hypothalamus. We hypothesized that the release of NPY has coordinated and integrated effects on energy metabolism in different tissues, such as adipocyte tissue, resulting in increased energy storage and decreased energy expenditure. Whether NPY has role in the molecular mechanism of human adipocyte tissue remains u...
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#2Ping-an Hu (CSU: Central South University)H-Index: 1
Last. Min Liu (CSU: Central South University)H-Index: 2
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To investigate the impact of neuropeptide Y (NPY) at different concentrations on the proliferation and differentiation of human adipose-derived stem cells (hADSCs).The hADSCs were separated and incubated with NPY at a range of concentrations 10(-6)-10(-15) mol/L. MTT assay was used to detect cell proliferation. Following the treatment of complete medium, NPY and insulin separately, cell differentiation was observed by Oil red O staining. In addition, Western blotting was performed to exam the le...
1 Citations