Jasna Metovic
University of Turin
CancerInternal medicineRadiologyPathologyOncologyGene expressionImmunohistochemistryPathologicalNeuroblastoma RAS viral oncogene homologBiopsyLung cancerCarcinomaLungNeuroendocrine tumorsDifferential diagnosisDuctal carcinomaAdenocarcinomaLung Neuroendocrine NeoplasmNeuroendocrine CarcinomasCancer researchThyroidBreast cancerMedicineBiology
46Publications
7H-index
172Citations
Publications 45
Newest
#1Enrico Costantino Falco (UNITO: University of Turin)H-Index: 1
#2Lorenzo DanieleH-Index: 15
Last. Mauro Papotti (UNITO: University of Turin)H-Index: 98
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Ectopic adrenal rests are a rare condition which can be found in various sites, generally in the retroperitoneum or pelvis along the path of gonadal descent. Their real prevalence is unknown. Males are more commonly affected, at least in the pediatric age. Adrenal rests are usually clinically silent and incidentally found in surgical samples, mostly in the pediatric population, and rarely in adults. With the aim of increasing knowledge and estimating the prevalence of ectopic adrenocortical tiss...
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Last. Mauro Papotti (UNITO: University of Turin)H-Index: 98
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: Pancreatic neuroendocrine tumors (PanNETs) are rare neoplasms that include even rarer variants that may pose different diagnostic problems, especially in fine needle aspiration cytology (FNAC). We describe the diagnostic clues of the amyloid-rich variant of PanNETs in endoscopic ultrasound (EUS)-guided fine needle aspiration cytology (EUS-FNAC). Three cases of PanNETs with an amyloid-rich stromal component were retrieved and retrospectively reviewed. For every case, the pancreatic lesion was i...
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#1Jasna Metovic (UNITO: University of Turin)H-Index: 7
#2Marco Barella (University of Milan)H-Index: 2
Last. Giuseppe Pelosi (University of Milan)H-Index: 69
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Neuroendocrine tumors and neuroendocrine carcinomas in the lung are distinct and separate entities featuring neuroendocrine differentiation, for which an accurate classification is clinically warranted. Three perspectives were addressed: (i) diagnostic tools, with the terminology to be used in either resection specimen or small-sized material; (ii) the so-called carcinoid tumors with elevated proliferation rates (mitotic and/or Ki-67 activity); (iii) predictive biomarkers based on immunohistoche...
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#1Jasna Metovic (UNITO: University of Turin)H-Index: 7
#2Isabella Castellano (UNITO: University of Turin)H-Index: 27
Last. Mauro Papotti (UNITO: University of Turin)H-Index: 98
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According to the 2019 WHO classification of breast tumors, neuroendocrine neoplasms (NENs) are classified into well-differentiated NE tumors (NET) and poorly differentiated NE carcinomas (NEC), while other breast cancers (BCs) of special and no special type with neuroendocrine (NE) features are not incorporated in this scheme anymore. We aimed to assess whether INSM1, a novel NE marker, could have a role in breast NEN subtyping. We selected 63 BCs operated from 2003 to 2018, classified as BCs wi...
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#1Marco VolanteH-Index: 71
#2Ida RapaH-Index: 22
Last. Mauro PapottiH-Index: 98
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The molecular mechanisms of adrenocortical carcinoma development are incompletely defined. De-regulation of cellular-to-extracellular matrix interactions and angiogenesis appear among mechanisms associated to the malignant phenotype. Our aim was to investigate, employing PCR-based array profiling, 157 molecules involved in cell-to-matrix interactions and angiogenesis in a frozen series of 6 benign and 6 malignant adrenocortical neoplasms, to identify novel pathogenetic markers. In 14 genes, a si...
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#1Jasna Metovic (UNITO: University of Turin)H-Index: 7
#2Fabrizio Bianchi (Casa Sollievo della Sofferenza)H-Index: 24
Last. Giuseppe Pelosi (University of Milan)H-Index: 69
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#1Jasna Metovic (UNITO: University of Turin)H-Index: 7
#2Marco BarellaH-Index: 2
Last. Giuseppe Pelosi (University of Milan)H-Index: 69
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Neuroendocrine neoplasms of the lung (Lung NENs) encompass NE tumors (NETs), which are in turn split into typical and atypical carcinoids, and NE carcinomas (NECs), which group together small-cell ...
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#1Jasna MetovicH-Index: 7
#2Fabrizio BianchiH-Index: 24
Last. Giuseppe PelosiH-Index: 69
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In the lung, neuroendocrine tumors (NETs), namely typical and atypical carcinoids, and neuroendocrine carcinomas (NECs), grouping small cell carcinoma (SCLC) and large cell neuroendocrine carcinoma (LCNEC), make up for distinct tumor entities according to epidemiological, genetic, pathologic and clinical data. The proper classification is essential in clinical practice for diagnosis, prognosis and therapy purposes. Through an extensive literature survey, three perspectives on lung NENs have been...
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#1Jasna Metovic (UNITO: University of Turin)H-Index: 7
#2Simona Osella Abate (UNITO: University of Turin)H-Index: 4
Last. Isabella Castellano (UNITO: University of Turin)H-Index: 27
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Background Many oncologists debate if lobular neoplasia (LN) is a risk factor or an obligatory precursor of more aggressive disease. This study has three aims: (i) describe the different treatment options (surgical resection vs observation), (ii) investigate the upgrade rate in surgically treated patients, and (iii) evaluate the long-term occurrences of aggressive disease in both operated and unoperated patients. Methods A series of 122 patients with LN bioptic diagnosis and follow-up informatio...
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#1Philippe ThuillierH-Index: 1
#2Virginia LiberiniH-Index: 2
Last. Désirée DeandreisH-Index: 30
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Aim: To evaluate if conventional Positron emission tomography (PET) parameters and radiomic features (RFs) extracted by 18F-FDG-PET/CT can differentiate among different histological subtypes of lung neuroendocrine neoplasms (Lu-NENs). Methods: Forty-four naive-treatment patients on whom 18F-FDG-PET/CT was performed for histologically confirmed Lu-NEN (n = 46) were retrospectively included. Manual segmentation was performed by two operators allowing for extraction of four conventional PET paramet...
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