Felix Hahn
University of Mainz
CancerInternal medicineRadiologyBiomedical engineeringUnivariate analysisArtificial intelligenceMultivariate statisticsFunnelStage (cooking)Radiological weaponMaterials scienceNatural language processingSarcopeniaLiver cancerChemotherapyCirrhosisHepatocellular carcinomaWristPelvisAnkleDiseaseLymphadenectomyThrombosisElbowCatheterIntrahepatic CholangiocarcinomaCross-sectional imagingTip catheterArea under the roc curveLiver functionMechanical thrombectomyIn patientRadiographyMultivariate analysisIncidence (epidemiology)Proportional hazards modelRisk factorArtificial neural networkClinical significanceMedicineCohortGastroenterology
Publications 43
#1Hauke Lang (University of Mainz)H-Index: 63
#2J. Baumgart (University of Mainz)H-Index: 8
Last. Friedrich Foerster (University of Mainz)H-Index: 11
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Background: Intrahepatic cholangiocarcinoma (iCCA) accounts for about 10% of primary liver cancer. Surgery is the only potentially curative treatment. We report on our current series of 229 consecutive hepatic resections for iCCA, which is one of the largest Western single-center series published so far. Methods: Between January 2008 to December 2020, a total of 286 patients underwent 307 surgical explorations for intended liver resection of iCCA at our department. Data were analyzed with regard...
#1Lukas Müller (University of Mainz)H-Index: 4
#2Felix Hahn (University of Mainz)H-Index: 6
Last. Daniel Pinto dos SantosH-Index: 12
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A combination of albumin-bilirubin (ALBI) grading and the Prognostic Nutritional Index (PNI) was identified recently as a highly predictive tool for patients with hepatocellular carcinoma (HCC) undergoing tumor ablation. The present study evaluated this combination in patients undergoing transarterial chemoembolization (TACE). Between 2010 and 2020, 280 treatment-naive patients were retrospectively identified. The influence of ALBI grade, PNI and the novel ALBI-PNI on the median overall survival...
#1Yasemin TanyildiziH-Index: 6
Last. Martin KramerH-Index: 22
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#1Simon Johannes Gairing (University of Mainz)
#2Felix Thol (University of Mainz)
Last. Marcus-Alexander Wörns (University of Mainz)H-Index: 11
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Incidence and mortality of intrahepatic cholangiocarcinoma (iCCA) have been increasing continuously. Recent studies suggest that the combination of palliative chemotherapy (pCTX) and transarterial chemoembolization (TACE) improves overall survival (OS). This study aimed to evaluate the outcome of patients treated with TACE and pCTX in unresectable iCCA at our tertiary care center. A group of 14 patients was treated with both pCTX and TACE. The non-randomized control group of 59 patients received...
#1Aline Mähringer-Kunz (University of Mainz)H-Index: 5
#2Franziska I Meyer (University of Cologne)
Last. Sebastian Schotten (University of Mainz)H-Index: 6
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BACKGROUND There is strong evidence that portal vein tumor thrombosis (PVTT) is associated with poor survival in patients with hepatocellular carcinoma (HCC). However, data regarding the clinical significance of hepatic vein tumor thrombosis (HVTT) is rare, particularly in Western patients. OBJECTIVE To determine the HVTT prevalence in a Western patient population and its impact on survival. METHODS We included 1310 patients with HCC treated in our tertiary referral center between January 2005 a...
#1Dominik Bettinger (University of Freiburg)H-Index: 18
#2Lukas Sturm (University of Freiburg)H-Index: 6
Last. Michael Schultheiss (University of Freiburg)H-Index: 13
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Abstract Background and aim TIPS implantation is an effective and safe treatment for complications of portal hypertension. Prediction of survival is important in these patients as they constitute a high-risk population per se. Therefore, the aim of our study was to develop an alternative prognostic model for accurate survival prediction after planned TIPS implantation. Methods A total of 1871 patients with de novo TIPS implantation for ascites or secondary prophylaxis of variceal bleeding were r...
10 CitationsSource
#1Fabian Bartsch (University of Mainz)H-Index: 6
#2Felix Hahn (University of Mainz)H-Index: 6
Last. Hauke Lang (University of Mainz)H-Index: 63
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Abstract Background Intrahepatic cholangiocarcinoma (ICC) still has a poor long-term outcome, even after complete resection. We investigated different parameters gathered in preoperative imaging and analyzed their influence on resectability, recurrence, and survival. Methods All patients who underwent exploration due to ICC between January 2008 and June 2018 were analyzed retrospectively. Kaplan-Meier model, log-rank test and Cox regression were used. Results Out of 184 patients, 135 (73.4%) und...
1 CitationsSource
#1Florian Jungmann (University of Mainz)H-Index: 7
#2Tobias Jorg (University of Mainz)H-Index: 2
Last. Roman Kloeckner (University of Mainz)H-Index: 14
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OBJECTIVES: We investigated the attitudes of radiologists, information technology (IT) specialists, and industry representatives on artificial intelligence (AI) and its future impact on radiological work. MATERIALS AND METHODS: During a national meeting for AI, eHealth, and IT infrastructure in 2019, we conducted a survey to obtain participants' attitudes. A total of 123 participants completed 28 items exploring AI usage in medicine. The Kruskal-Wallis test was used to identify differences betwe...
3 CitationsSource
#1Lukas Müller (University of Mainz)H-Index: 4
#2Fabian Stoehr (University of Mainz)
Last. Roman Kloeckner (University of Mainz)H-Index: 14
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Treatment of hepatocellular carcinoma (HCC) depends on the stage of disease. In the Western Hemisphere, the Barcelona Clinic Liver Cancer classification (BCLC) is the preferred staging system. Approximately one-third of patients initially present with intermediate-stage disease. For these patients, transarterial chemoembolization (TACE) is the treatment of choice. However, the intermediate-stage comprises a heterogeneous subgroup of patients with considerable differences in tumor burden and live...
Several scoring systems have been devised to objectively predict survival for patients with intrahepatic cholangiocellular carcinoma (ICC) and support treatment stratification, but they have failed external validation. The aim of the present study was to improve prognostication using an artificial intelligence-based approach. We retrospectively identified 417 patients with ICC who were referred to our tertiary care center between 1997 and 2018. Of these, 293 met the inclusion criteria. Establish...