Changchun Zhou
Sichuan University
CeramicBiomedical engineeringFabricationComposite materialRegeneration (biology)NanotechnologyChemistryMaterials scienceBiocompatibilityApatiteBone tissueBiofabricationBone regenerationChemical engineeringTissue engineeringTitaniumCalcium3D printingPorosityScaffold
44Publications
17H-index
869Citations
Publications 39
Newest
#1Xuan PeiH-Index: 8
#2Lina WuH-Index: 6
Last. Xingdong ZhangH-Index: 57
view all 13 authors...
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#1Changchun Zhou (Sichuan University)H-Index: 17
#2Kefeng Wang (Sichuan University)H-Index: 28
Last. Xingdong Zhang (Sichuan University)H-Index: 57
view all 10 authors...
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#1Xuan Pei (Sichuan University)H-Index: 8
#2Lina Wu (Sichuan University)H-Index: 6
Last. Xingdong Zhang (Sichuan University)H-Index: 57
view all 12 authors...
Abstract Orthopedic implants with heterogeneous porous structures were known as ideal bone osteointegration. This research introduced the selective laser melting (SLM), finite element analysis (FEA), and a hydrothermal process (HT) for manufacturing a three-level heterogeneous porous structure. The macroporous structure was designed via CAD and micropores were tuned via laser power regulation. A nano-size layer of hydroxyapatite crystals was coated by an HT process. The mechanical properties wer...
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#1Boqing Zhang (Sichuan University)H-Index: 6
#2Ling Wang (Sichuan University)H-Index: 1
Last. Xingdong Zhang (Sichuan University)H-Index: 57
view all 10 authors...
Abstract Polylactic acid/Hydroxyapatite (PLA/HA) composite was widely studied and applied in the field of biomaterials for its good processability, bioactivity, and mechanical properties. In addition to traditional preparation methods, additive manufacturing has also been adopted to prepare PLA/HA composites with customized geometries. This work combined the comprehensive optimized PLLA (L-polylactic acid)/nano-HA (nHA) composite with the low-cost and stable Fused deposition modeling (FDM) techn...
1 CitationsSource
#1Chenxi Zhang (Sichuan University)H-Index: 2
#2Didi HuiH-Index: 2
Last. Changchun Zhou (Sichuan University)H-Index: 17
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Chitosan is a biodegradable and biocompatible natural polysaccharide that has a wide range of applications in the field of dentistry due to its functional versatility and ease of access. Recent studies find that chitosan and its derivatives can be embedded in materials for dental adhesives, barrier membranes, bone replacement, tissue regeneration, and antimicrobial agent to better manage oral diseases. In this paper, we provide a comprehensive overview on the preparation, applications, and major...
4 CitationsSource
#1Haoyuan Lei (Sichuan University)H-Index: 3
#2Tao Yi (Sichuan University)H-Index: 2
Last. Xingdong Zhang (Sichuan University)H-Index: 57
view all 11 authors...
Abstract Scaffold micro-topological structure plays an important role in the regulation of cell behavior in bone tissue engineering. This paper investigated the effect of 3D printing parameters on the scaffold micro-topological structure and its subsequent cell behaviors. By setting of different 3D printing parameters, i.e., the 3D printing laser power, the scanning interval and the thickness of sliced layers, the highest resolution up to 20 μm can be precisely fabricated. Scaffolds' characteriz...
1 CitationsSource
#1Fei Xing (Sichuan University)H-Index: 10
#1Fei Xing (Sichuan University)H-Index: 2
Last. Xingdong Zhang (Sichuan University)H-Index: 57
view all 12 authors...
2 CitationsSource
#1Lina Wu (Sichuan University)H-Index: 6
#2Changchun Zhou (Sichuan University)H-Index: 17
Last. Xingdong Zhang (Sichuan University)H-Index: 57
view all 10 authors...
Scaffolds with a biomimetic hierarchy micro/nanoscale pores play an important role in bone tissue regeneration. In this study, multilevel porous calcium phosphate (CaP) bioceramic orthopedic implants were constructed to mimic the micro/nanostructural hierarchy in natural wood. The biomimetic hierarchical porous scaffolds were fabricated by combining three-dimensional (3D) printing technology and hydrothermal treatment. The first-level macropores (∼100-600 μm) for promoting bone tissue ingrowth w...
3 CitationsSource
#1Xuan Pei (Sichuan University)H-Index: 8
#2Lina Wu (Sichuan University)H-Index: 6
Last. Xingdong Zhang (Sichuan University)H-Index: 57
view all 13 authors...
Biofabrication of personalized titanium scaffold mimicking that of the osteocyte microenvironment is challenging due to its complex geometrical cues. The effect of scaffolds geometrical cues and implantation sites on osteogenesis is still not clear. In this study, personalized titanium scaffolds with homogeneous diamond-like structures mimicking that of the osteocyte microenvironment were precisely designed and fabricated by selected laser melting method. The effects of different geometric cues,...
5 CitationsSource
#1Wei Peng (Sichuan University)H-Index: 1
#2Zhiyu Peng (Sichuan University)H-Index: 1
Last. Yongwei Wang (Sichuan University)
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Plastic surgery is a broad field, including maxillofacial surgery, skin flaps and grafts, liposuction and body contouring, breast surgery, and facial cosmetic procedures. Due to the requirements of plastic surgery for the biological safety of materials, biomaterials are widely used because of its superior biocompatibility and biodegradability. Currently, there are many kinds of biomaterials clinically used in plastic surgery and their applications are diverse. Moreover, with the rise of three-di...
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