Asim Afaq
University College Hospital
Intraclass correlationCorrelationInternal medicineRadiologyUrologyPET-CTPathologyMagnetic resonance imagingUltrasoundOncologyStage (cooking)Medical physicsPositron emission tomographyProstateBiochemical recurrenceBrachytherapyMetastasisProstatectomyProstate cancerSalvage therapyProstate-specific antigenProstate BedNuclear medicineMedical imagingRadiation therapyColorectal cancerEffective diffusion coefficientMedicine
51Publications
14H-index
880Citations
Publications 49
Newest
#1Balaji Ganeshan (UCL: University College London)H-Index: 32
#2Kenneth A. Miles (UCL: University College London)H-Index: 56
Last. Ashley M. Groves (UCL: University College London)H-Index: 47
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To assess the capability of fractional water content (FWC) texture analysis (TA) to generate biologically relevant information from routine PET/MRI acquisitions for colorectal cancer (CRC) patients. Thirty consecutive primary CRC patients (mean age 63.9, range 42-83 years) prospectively underwent FDG-PET/MRI. FWC tumor parametric images generated from Dixon MR sequences underwent TA using commercially available research software (TexRAD). Data analysis comprised (1) identification of functional ...
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#1Asim Afaq (UCL: University College London)H-Index: 14
#2Heather Payne (UCL: University College London)H-Index: 10
Last. Jamshed Bomanji (UCL: University College London)H-Index: 52
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Objectives: To assess the safety and clinical impact of a novel, kit-based formulation of 68Ga‐THP PSMA positron emission tomography/computed tomography (PET/CT) when used to guide the management of patients with prostate cancer (PCa). Methods: Patients were prospectively recruited in to one of: Group A: high-risk untreated prostate cancer; Gleason score >4+3, or PSA >20 ng/mL or clinical stage >T2c. Group B: biochemical recurrence (BCR) and eligible for salvage treatment after radical prostatec...
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#1Andrew Scarsbrook (Leeds Teaching Hospitals NHS Trust)H-Index: 29
#2David Bottomley (Leeds Teaching Hospitals NHS Trust)H-Index: 20
Last. Fergus V. Gleeson (University of Oxford)H-Index: 57
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Abstract Purpose Early and accurate localisation of lesions in patients with biochemical recurrence (BCR) of prostate cancer may guide salvage therapy decisions. The present study, XXX, aimed to evaluate the impact of 18F-fluciclovine on management of men with BCR of prostate cancer. Methods Men with a first episode of BCR following curative-intent primary therapy were enrolled at 6 UK sites. Patients underwent 18F-fluciclovine PET/CT according to standardised procedures. Clinicians documented m...
14 CitationsSource
#1Asim Afaq (UCLH: University College Hospital)H-Index: 14
#2Ming Young Simon Wan (UCLH: University College Hospital)H-Index: 1
Last. Jamshed Bomanji (UCLH: University College Hospital)H-Index: 52
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1255 Objectives: The primary objective was to evaluate the phenomenon of benign bone marrow uptake which has been described with 18F-PSMA-1007 using PET/MRI. Secondary objectives were to review the initial experience and technical feasibility of staging and restaging of prostate cancer using 18F-PSMA-1007 PET/MRI and to assess if a pelvic section of Diffusion Weighted Imaging provided any additional lesion detection over the standard PET/MRI dataset. Methods: Thirty-four consecutive patients wer...
1 Citations
#1Asim Afaq (UCLH: University College Hospital)H-Index: 14
#2Heather Payne (UCLH: University College Hospital)H-Index: 20
Last. Jamshed Bomanji (UCLH: University College Hospital)H-Index: 52
view all 15 authors...
1259 Objectives: The primary objective of the study was to evaluate the impact of a novel, kit-based formulation of 68Ga‐THP‐PSMA positron emission tomography/computed tomography (PET/CT) on the management of patients with prostate cancer (PCa). The secondary objective of the study was to evaluate the safety of 68Ga‐THP-PSMA in patients with PCa. Methods: Patients with histopathologically proven prostate cancer with potentially operable, untreated disease, Gleason score >4+3 , or PSA >20 ng/mL o...
#2Asim AfaqH-Index: 14
Last. Asim AfaqH-Index: 4
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#1Dimitrios Priftakis (UCLH: University College Hospital)H-Index: 2
#2Asim AfaqH-Index: 14
Last. Jamshed BomanjiH-Index: 52
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Two cases with Ga-PSMA-avid prostate cancer recurrence in the vas deferens are presented. These cases highlight the clinical importance of imaging the pattern of local prostate cancer recurrence and the potential difficulties that arise due to the altered anatomy in the prostate bed after prostatectomy or radiotherapy.
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#1Mina Kim (UCL: University College London)H-Index: 3
#2F Torrealdea (UCLH: University College Hospital)H-Index: 1
Last. Xavier GolayH-Index: 63
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Background: The aim of this study was to translate dynamic glucose enhancement (DGE) body magnetic resonance imaging (MRI) based on the glucose chemical exchange saturation transfer (glucoCEST) signal to a 3 T clinical field strength. Methods: An infusion protocol for intravenous (i.v.) glucose was optimised using a hyperglycaemic clamp to maximise the chances of detecting exchange-sensitive MRI signal. Numerical simulations were performed to define the optimum parameters for glucoCEST measureme...
6 CitationsSource
#1Asim Afaq (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 14
#2Peter J. EllH-Index: 77
Last. Jamshed BomanjiH-Index: 52
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