Jong Min Kim
GlycationChemistryHouttuynia cordataAldose reductaseQuercitrinAfzelinFlavonolsProtocatechuic acidQuercetinAdvanced Glycation EndproductsPuerariae radixBiochemistryTraditional medicineMedicine
10Publications
5H-index
66Citations
Publications 10
Newest
#1Se Chul HongH-Index: 4
#2Nam Hee YooH-Index: 1
Last. Mi Kyung PyoH-Index: 4
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#2Jong Min KimH-Index: 5
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#1Jong Min KimH-Index: 5
Last. Nak-Sul SeongH-Index: 13
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− In this study, the inhibitory effect on advanced glycation end products (AGEs) formation of 43 Korean herbal medicines has been evaluated. Among them, 16 Korean herbal medicines were showed to have significant effect (IC50; <50 μg/ml) compared to positive reference, aminoguandine (IC50: 76.47±4.81 μg/ml). Especially, five herbal medicines, Rubus coreanus (leaves, IC50: 4.49±0.03 μg/ml), Rubus coreanus (twigs, IC50: 3.80±0.34 μg/ml), Ampleopsis brevipedunculata (stems, IC50: 7.43±0.09 μg/ml), L...
#1Dae Sik JangH-Index: 30
#2Nam Hee YooH-Index: 7
Last. Jin Sook KimH-Index: 35
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Schizandra chinensis fruits (SC) have been used as a traditional Oriental medicine for treatments of many stress-induced diseases. In the present study, we investigated the protective effect of SC aqueous extract (SC-Ex) in the inflammatory diseases of intestine using a mouse model of ulcerative colitis. An experimental colitis was induced by daily treatment with 5% dextran sulfate sodium (DSS). SC-Ex was orally administered from day 2 of DSS treatment in a dose-dependent manner. Administration ...
#1Dae Sik JangH-Index: 2
#2Jong Min KimH-Index: 5
Last. Jin Sook KimH-Index: 5
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A new 2-arylbenzofuran, puerariafuran (1), as well as three known compounds, coumestrol (2), daidzein (3), and genistein (4), were isolated from a MeOH extract of the roots of Pueraria lobata as active constituents, using an in vitro bioassay based on the inhibition of advanced glycation end products (AGEs) to monitor chromatographic fractionation. The structure of 1 was determined by spectroscopic data interpretation, particularly by extensive 1D and 2D NMR studies. All the isolates (1—4) were ...
Source
#1Dae Sik JangH-Index: 30
#2Jong Min KimH-Index: 5
Last. Jin Sook KimH-Index: 35
view all 7 authors...
A 4,5-dioxoaporphine type alkaloid, cepharadione B (1), a phenolic acid, protocatechuic acid (2), and flavonols, quercetin (3), afzelin (4), and quercitrin (5), were isolated from the EtOAc-soluble extract of the whole plants of Houttuynia cordata. All the isolates (1-5) were subjected to in vitro bioassays to evaluate advanced glycation end products (AGEs) formation and rat lens aldose reductase (RLAR) inhibitory activity. The three flavonols 3-5 exhibited a significant inhibitory activity on A...
Fractionation of an EtOAc-soluble extract of the stems of Rumex japonicus led to the isolation of two new 24-norursane type triterpenoids, 2α,3α,19α-trihydroxy-24-norurs-4(23),12-dien-28-oic acid (1) and 4(R),23-epoxy-2α,3α,19α-trihydroxy-24-norurs-12-en-28-oic acid (2), along with the known compounds myrianthic acid (3), tormentic acid, and emodin. The structures of 1 and 2 were elucidated by spectroscopic methods, particularly by extensive 1D and 2D NMR studies.
Source
#1Jong Min KimH-Index: 5
Last. Jin Sook KimH-Index: 35
view all 5 authors...
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