Edoardo Savarino
University of Padua
Internal medicineRadiologySurgeryIntensive care medicineHeartburnGERDNerdEsophagusInflammatory bowel diseaseEndoscopyHigh resolution manometryImpedance–pH monitoringDiseaseCrohn's diseaseProton-pump inhibitorEosinophilic esophagitisIn patientRefluxMedicineGastroenterology
808Publications
60H-index
8,166Citations
Publications 805
Newest
#1Marzio FrazzoniH-Index: 31
#2Leonardo Frazzoni (UNIBO: University of Bologna)H-Index: 21
Last. Edoardo Savarino (UNIPD: University of Padua)H-Index: 60
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#1Ahmad Albshesh (Sheba Medical Center)H-Index: 3
#2Joshua Taylor (MGH: Montreal General Hospital)
Last. Claire LiefferinckxH-Index: 6
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Background: Multiple studies have described the effectiveness of ustekinumab (UST) and vedolizumab (VDZ) in patients with Crohn’s disease (CD) failing anti- Tumor necrosis factors (TNFs); however, the effectiveness of VDZ or UST as a third-class biologic has not yet been described. Aims and Methods: In this retrospective multicenter cohort study, we aimed to investigate the effectiveness of VDZ and UST as a third-class biologic in patients with CD. Results: Two-hundred and four patients were inc...
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#1Mentore Ribolsi (Università Campus Bio-Medico)H-Index: 20
#2Marzio FrazzoniH-Index: 31
Last. Edoardo Savarino (UNIPD: University of Padua)H-Index: 60
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BACKGROUND The Lyon Consensus delineates impedance-pH parameters that can demonstrate/exclude gastro-oesophageal reflux disease (GERD). In patients with acid exposure time between 4% and 6%, GERD diagnosis has been considered inconclusive. In these cases, mean nocturnal baseline impedance (MNBI) and post-reflux swallow-induced peristaltic wave (PSPW) index may either confirm or refute GERD diagnosis and represent predictors of proton pump inhibitor (PPI) response. AIMS To investigate the diagnos...
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#1Pierfrancesco Visaggi (UniPi: University of Pisa)H-Index: 2
#2Brigida Barberio (UNIPD: University of Padua)H-Index: 7
Last. Edoardo Savarino (UNIPD: University of Padua)H-Index: 60
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Esophageal cancer (EC) is the seventh most common cancer and the sixth cause of cancer death worldwide. Histologically, esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC) account for up to 90% and 20% of all ECs, respectively. Clinical symptoms such as dysphagia, odynophagia, and bolus impaction occur late in the natural history of the disease, and the diagnosis is often delayed. The prognosis of ESCC and EAC is poor in advanced stages, being survival rates less than 2...
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#1Marco LosaH-Index: 3
#2Salomon M. ManzH-Index: 1
Last. Daniel PohlH-Index: 22
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Background null Little is known about possible underlying psychological abnormalities and physiology of reflux hypersensitivity (RH) as defined in the recent Rome IV classification. We aimed to assess markers of psychological comorbidity as well as gastro-esophageal reflux measurements in RH patients compared to controls and also in patients with functional heartburn (FH) and non-erosive reflux disease (NERD) versus controls. null Methods null Data of 304 patients visiting our Functional Diagnos...
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Abstract null null Background null Long-standing inflammation leads to esophageal remodeling with stricture formation in patients with eosinophilic esophagitis (EoE). The ability of proton pump inhibitors (PPI) to reverse endoscopic features of fibrosis is still unknown. null null null Objective null To investigate the effect of a short course of PPI treatment in reducing endoscopic findings indicative of esophageal fibrosis in EoE patients. null null null Methods null Cross-sectional analysis o...
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#1Marco Vincenzo Lenti (UNIPV: University of Pavia)H-Index: 16
#2Edoardo SavarinoH-Index: 60
Last. Valeria Longoni (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)
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Abstract null null Background null Eosinophilic oesophagitis (EoE) may lead to severe complications if not promptly recognised. null null null Aims null To assess the diagnostic delay in patients with EoE and to explore its risk factors. null null null Methods null EoE patients followed-up at eight clinics were included via retrospective chart review. Diagnostic delay was estimated as the time lapse occurring between the appearance of the first likely symptoms indicative of EoE and the final dia...
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#1Brigida Barberio (UNIPD: University of Padua)H-Index: 7
#2Ciaran Judge (St James's University Hospital)H-Index: 1
Last. Alexander C. Ford (University of Leeds)H-Index: 86
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Summary null Background null Functional constipation is a common functional bowel disorder in the community, which has a varying prevalence across cross-sectional surveys. We did a contemporaneous systematic review and meta-analysis of studies using comparable methodology and all iterations of the Rome criteria to estimate the global prevalence of functional constipation. null Methods null In this systematic review and meta-analysis, we searched MEDLINE, Embase, and Embase Classic from Jan 1, 19...
1 CitationsSource
#1Mentore Ribolsi (Università Campus Bio-Medico)H-Index: 20
#2Marzio FrazzoniH-Index: 31
Last. Edoardo Savarino (UNIPD: University of Padua)H-Index: 60
view all 11 authors...
BACKGROUND Esophageal chemical clearance has been evaluated with the post-reflux swallow-induced peristaltic wave (PSPW) index. The factors triggering PSPW in Gastro-esophageal reflux disease (GERD) have not yet been investigated. This multicenter study was aimed at evaluating the characteristics of reflux episodes associated with PSPW occurrence in patients with typical GERD symptoms. METHODS Impedance-pH tracings from patients with typical reflux symptoms were analyzed. Sixteen healthy subject...
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#1Mentore Ribolsi (Università Campus Bio-Medico)H-Index: 20
#2Edoardo Savarino (UNIPD: University of Padua)H-Index: 60
Last. Chandra Prakash Gyawali (WashU: Washington University in St. Louis)H-Index: 26
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Background/Aims The role of esophageal high-resolution manometry (HRM) within Lyon consensus phenotypes, especially patients with inconclusive gastroesophageal reflux disease (GERD) evidence, has not been fully investigated. In this multicenter, observational study we aim to compare HRM parameters in patients with GERD stratified according to the Lyon consensus. Methods Clinical and endoscopic data, HRM and multichannel intraluminal impedance-pH (MII-pH) studies performed off proton pump inhibit...
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