Irvin M. Modlin
Yale University
HistamineInternal medicineEndocrinologyPathologyMolecular biologyChemistryEnterochromaffin-like cellSomatostatinGastrinGastric acidGastric glandsParietal cellGastric mucosaGene clusterSecretionCancer researchBiochemistryMedicineIntracellularBiologyProtein kinase A
42Publications
11H-index
270Citations
Publications 50
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#1Mark KiddH-Index: 4
#2Alexandra KitzH-Index: 2
Last. Irvin M. ModlinH-Index: 11
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#1Irvin M. ModlinH-Index: 11
#2Mark KiddH-Index: 4
Last. Faidon-Marios LaskaratosH-Index: 7
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#1Lisa BodeiH-Index: 3
#1Lisa BodeiH-Index: 50
Last. Irvin M. ModlinH-Index: 11
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#1Mariano J. AlvarezH-Index: 3
#1Mariano J. AlvarezH-Index: 3
Last. Andrea CalifanoH-Index: 76
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#1Lisa BodeiH-Index: 3
#1Lisa BodeiH-Index: 50
Last. Irvin M. ModlinH-Index: 11
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#1Lisa BodeiH-Index: 3
#1Lisa BodeiH-Index: 50
Last. Irvin M. ModlinH-Index: 11
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#1Ashley CliftH-Index: 1
#1Ashley K. CliftH-Index: 13
Last. Andrea FrillingH-Index: 44
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#1Brian G. RubinH-Index: 1
#2Garth H. BallantyneH-Index: 28
Last. Irvin M. ModlinH-Index: 11
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\s=b\ Disagreement persists as to whether all patients with inguinal hernia should undergo screening examinations for colorectal cancers before hernia repair. The purpose of this study was to prospectively evaluate the effectiveness of flexible sigmoidoscopy (FS) as a screening examination for these patients. In an 18-month period, 110 patients with inguinal hernia (99% men) with an average age of 63\m=+-\10years underwent FS. Diverticulosis was found in 36% of the patients, colorectal polyps in...
#1Lisa BodeiH-Index: 3
#1Lisa BodeiH-Index: 50
Last. Irvin M. ModlinH-Index: 11
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#1Mark KiddH-Index: 4
#2Ignat DrozdovH-Index: 37
Last. Irvin M. ModlinH-Index: 11
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A multianalyte algorithmic assay (MAAA) identifies circulating neuroendocrine tumor (NET) transcripts (nZ51) with a sensitivity/specificity of 98%/97%. We evaluated whether blood measurements correlated with tumor tissue transcript analysis. The latter were segregated into gene clusters (GC) that defined clinical ‘hallmarks’ of neoplasia. A MAAA/cluster integrated algorithm (CIA) was developed as a predictive activity index to define tumor behavior and outcome. We evaluated three groups. Group 1...