Pradeep Kumar
University of the Witwatersrand
Biomedical engineeringNuclear chemistryNanoparticleFourier transform infrared spectroscopyNanotechnologyOrganic chemistryChemistryPolymer chemistryMaterials scienceIn vivoSwellingChitosanDrug deliveryDrugChemical engineeringChromatographyPolymerMedicineZeta potentialPharmacology
385Publications
31H-index
4,400Citations
Publications 378
Newest
#1Jyoti Mundlia (Guru Jambheshwar University of Science and Technology)H-Index: 3
#2Munish Ahuja (Guru Jambheshwar University of Science and Technology)H-Index: 23
Last. Pradeep Kumar (University of the Witwatersrand)H-Index: 31
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The gellan gum was coupled with hydrophobic polyphenols, curcumin and naringenin using dicyclohexylcarbodiimide and dimethylaminopyridine reaction. The formation of conjugates was ascertained by sp...
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#1Tayo Alex Adekiya (University of the Witwatersrand)H-Index: 5
#2Pradeep Kumar (University of the Witwatersrand)H-Index: 31
Last. Yahya E. Choonara (University of the Witwatersrand)H-Index: 34
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INTRODUCTION : Among all the anti-schistosomal drug, praziquantel has been the most widely used. However, some major challenges have been faced using the drug in the treatment of schistosome infections. AREAS COVERED : Several approaches used in the synthesis of praziquantel aimed at reducing the time and cost of production, the toxicity and experimental harsh conditions are discussed. Also, patented methods involved in the pharmaceutical reformulation of praziquantel in the treatment of diverse...
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#1Keshav Raj Paudel (UTS: University of Technology, Sydney)H-Index: 13
#2Ridhima Wadhwa (UTS: University of Technology, Sydney)H-Index: 9
Last. Kamal Dua (Centenary Institute)H-Index: 25
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Non-small cell lung cancer (NSCLC) is one of the major causes of cancer-related mortality globally. Despite the availability of therapeutic options, the improvement in patient survival is yet to be achieved. Recent advances in natural product (e.g., Rutin) research, therapeutic nanotechnology and especially the combination of both could aid in achieving significant improvements in the treatment or management of NSCLC. In this study, we explore the anti-cancer activity of Rutin-loaded liquid crys...
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The demand for biodegradable sustained release carriers with minimally invasive and less frequent administration properties for therapeutic proteins and peptides has increased over the years. The purpose of achieving sustained minimally invasive and site-specific delivery of macromolecules led to the investigation of a photo-responsive delivery system. This research explored a biodegradable prolamin, zein, modified with an azo dye (DHAB) to synthesize photo-responsive azoprolamin (AZP) nanospher...
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Abstract Background This is the first randomized controlled trial of trabeculectomy with Ex-Press Shunt versus Ologen implant in primary open-angle glaucoma (POAG) in Indian eyes. Methods A prospective randomized controlled trial of patients of POAG treated with two different methods of augmented trabeculectomy. Group A with Ex-PRESS shunt (P50 model) and Group B with Ologen implant. Surgical success was defined as intraocular pressure of 21 mm Hg or lower at 6 months postoperative. Results N = ...
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#1Thashree Marimuthu (University of the Witwatersrand)H-Index: 11
#2Pradeep Kumar (University of the Witwatersrand)H-Index: 31
Last. Yahya E. Choonara (University of the Witwatersrand)H-Index: 34
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INTRODUCTION : Water soluble polysaccharides are versatile structural materials that can be used for the design of biocompatible hydrogels and wet dressings in wound healing applications. Glycol chitosan (GC) is an example of a multifunctional water-soluble chitosan derivative that has inherent wound healing properties and reactive sites for chemical modification. AREAS COVERED : United States (US) patent US2019202998A1 describes the preparation of a novel wound healing technology based on a thr...
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#1Rakesh K Sindhu (Chitkara University)H-Index: 2
#2Harnoor Kaur (Chitkara University)
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Nanoscale robotics have the ability that it can productively transform multiple energy sources into motion and strength which reflects an expeditiously appearing and captivating area for research of robotics. In today's plethora, biomedical nanorobotics played an intricate character with numerous units of robots working at the pathological site in a coordinated manner. The synergistic action of the several nanorobotics has been employed for the fulfilment of the task such as large-scale detoxifi...
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#1Loveleen Kaur (Chitkara University)H-Index: 2
#2Ajay Kumar Thakur (Chitkara University)H-Index: 1
Last. Inderbir Singh (Chitkara University)H-Index: 15
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Present study was aimed to synthesize and characterize Chitosan-Catechol conjugates and to design and develop mucoadhesive pellets loaded with lafutidine. SEM images indicated the presence of fibro...
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