Miao Wang
Shenyang Pharmaceutical University
Therapeutic effectPharmacokineticsChemical compositionMass spectrometryFourier transform ion cyclotron resonanceCarbohydrate metabolismHigh-performance liquid chromatographyChemistryDecoctionMetabolic pathwayRadixIn vivoMetabolomicsFormic acidAtorvastatinGynostemma pentaphyllumFatty liverHyperlipidemiaChemical constituentsChromatographyLipid metabolismPharmacology
32Publications
9H-index
184Citations
Publications 32
Newest
#1Fa He (SPU: Shenyang Pharmaceutical University)H-Index: 1
#2Miao Wang (SPU: Shenyang Pharmaceutical University)H-Index: 9
Last. Chunjie Zhao (SPU: Shenyang Pharmaceutical University)H-Index: 6
view all 6 authors...
Gerbera anandria (Compositae) was extracted with 75% ethanol and the residue was fractionated using light petroleum, chloroform and ethyl acetate. The constituents of the extracts were separated by column chromatography employing solvents of different polarity. Column chromatography of the light petroleum fraction resulted in the isolation of methyl hexadecanoate, while the chloroform fraction afforded xanthotoxin, 2-hydroxy-6-methylbenzoic acid, 7-hydroxy-1(3H)-isobenzofuranone, a mixture of β-...
15 CitationsSource
#1Miao Wang (SPU: Shenyang Pharmaceutical University)H-Index: 9
#2Fei Wang (NU: Northeastern University)H-Index: 2
Last. Chunjie Zhao (SPU: Shenyang Pharmaceutical University)H-Index: 6
view all 6 authors...
Gynostemma pentaphyllum (GP) is widely used for the treatment of diseases such as hyperlipidemia, fatty liver and obesity in China, and atorvastatin is broadly used as an anti-hyperlipidemia drug. This research focuses on the plasma and liver metabolites in the following four groups of rats: control, a hyperlipidemia model, a hyperlipidemia model treated with GP and a hyperlipidemia model treated with atorvastatin. Using 1H-NMR-based metabonomics, we elucidated the therapeutic mechanisms of GP a...
29 CitationsSource