Renaud de Crevoisier
University of Rennes
CancerInternal medicineRadiologyUrologySurgeryMagnetic resonance imagingOncologyArtificial intelligenceImage registrationPattern recognitionProstateProstate cancerRectumPopulationNuclear medicineComputer visionComputer scienceRadiation therapyMedicineImage-guided radiation therapy
Publications 137
#1Alexandre EscandeH-Index: 14
#2Pierre MarounH-Index: 10
Last. Cyrus ChargariH-Index: 32
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Abstract Background No study has examined the possibility to perform an organ sparing strategy in older patients with penile carcinoma, and amputation is frequently proposed. We report our experience of interstitial brachytherapy for the conservative treatment of penile carcinoma confined to the glans in patients aged of 70 years and more. Methods A total of 55 patients candidates to conservative brachytherapy were identified. Median age was 73.8 years (range: 70–95 years). Patients underwent a ...
2 CitationsSource
#1A. LargentH-Index: 5
#2Jean-Claude NunesH-Index: 14
Last. Oscar AcostaH-Index: 21
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Dose calculation from MRI is a topical issue. New treatment systems combining a linear accelerator with a MRI have been recently being developed. MRI has good soft tissue contrast without ionizing radiation exposure. However, unlike CT, MRI does not provide electron density information necessary for dose calculation. We propose in this paper a machine learning method to simulate a CT from a target MRI and co-registered CT-MRI training set. Ten prostate MR and CT images have been considered. Firs...
4 CitationsSource
#1Frederic Commandeur (French Institute of Health and Medical Research)H-Index: 13
#1Frederic Commandeur (French Institute of Health and Medical Research)H-Index: 6
Last. Oscar Acosta (French Institute of Health and Medical Research)H-Index: 21
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External radiotherapy is a major clinical treatment for localized prostate cancer. Currently, computed tomography (CT) is used to delineate the prostate and to plan the radiotherapy treatment. However, CT images suffer from a poor soft-tissue contrast and do not allow an accurate organ delineation. On the contrary, magnetic resonance imaging (MRI) provides rich details and high soft-tissue contrast, allowing tumor detection. Thus, the intraindividual propagation of MRI delineations toward the pl...
13 CitationsSource
#2K. Gnep (University of Rennes)H-Index: 8
Last. Renaud de Crevoisier (University of Rennes)H-Index: 28
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BACKGROUND: To identify predictors of acute and late rectal toxicity following prostate cancer radiotherapy (RT), while integrating the potential impact of RT technique, dose escalation, and moderate hypofractionation, thus enabling us to generate a nomogram for individual prediction. METHODS: In total, 972 patients underwent RT for localized prostate cancer, to a total dose of 70 Gy or 80 Gy, using two different fractionations (2 Gy or 2.5 Gy/day), by means of several RT techniques (3D conforma...
12 CitationsSource
#1Joël Castelli (University of Applied Sciences Western Switzerland)H-Index: 17
#2Adrien DepeursingeH-Index: 26
Last. John O. PriorH-Index: 34
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PurposeIn the context of oropharyngeal cancer treated with definitive radiotherapy, the aim of this retrospective study was to identify the best threshold value to compute metabolic tumor volume (MTV) and/or total lesion glycolysis to predict local-regional control (LRC) and disease-free survival.Me
9 CitationsSource
#1Richard Rios (National University of Colombia)H-Index: 3
#2Renaud de Crevoisier (University of Rennes)H-Index: 28
Last. Oscar Acosta (University of Rennes)H-Index: 21
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Abstract In radiotherapy for prostate cancer irradiation of neighboring organs at risk may lead to undesirable side-effects. Given this setting, the bladder presents the largest inter-fraction shape variations hampering the computation of the actual delivered dose vs. planned dose. This paper proposes a population model, based on longitudinal data, able to estimate the probability of bladder presence during treatment, using only the planning computed tomography (CT) scan as input information. As...
8 CitationsSource
Apr 18, 2017 in ISBI (International Symposium on Biomedical Imaging)
#1Vivien Aubert (French Institute of Health and Medical Research)H-Index: 2
#2Oscar Acosta (French Institute of Health and Medical Research)H-Index: 21
Last. Renaud de Crevoisier (French Institute of Health and Medical Research)H-Index: 28
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Objectives: Using in silico simulations from histopathological cancer prostate specimen, the objectives were to identify the total dose corresponding to various fractionations necessary to destroy the tumor cells (50% to 99.9%) and to assess the impact of the Gleason score on those doses.
1 CitationsSource
#1Antoine Simon (University of Rennes)H-Index: 17
#2Amandine Le Maitre (University of Rennes)H-Index: 3
Last. Renaud de Crevoisier (University of Rennes)H-Index: 28
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Purpose To assess dose uncertainties resulting from the dose deformation–invariance hypothesis in prostate cone beam computed tomography (CT)–based image guided radiation therapy (IGRT), namely to evaluate whether rigidly propagated planned dose distribution enables good estimation of fraction dose distributions. Methods and Materials Twenty patients underwent a CT scan for planning intensity modulated radiation therapy–IGRT delivering 80 Gy to the prostate, followed by weekly CT scans. Two meth...
2 CitationsSource
#1Florent VilotteH-Index: 2
#2Mickael AntoineH-Index: 1
Last. Paul SargosH-Index: 18
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In the era of intensity modulated radiation therapy, image guided radiotherapy (IGRT) appears crucial to control dose delivery and to promote dose escalation while allowing healthy tissue sparing. The place of IGRT following radical prostatectomy is poorly described in the literature. This review aims to highlight some key-points on the different IGRT techniques applicable to prostatic bed radiotherapy. Furthermore, methods used to evaluate target motion and to reduce planning target volume marg...
4 CitationsSource
#1Enrique ChajonH-Index: 13
#2Joël Castelli (University of Rennes)H-Index: 17
Last. Renaud de Crevoisier (University of Rennes)H-Index: 28
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Abstract Radiotherapy (RT) is one of the main components in the treatment of cancer. The better understanding of the immune mechanisms associated with tumor establishment and how RT affects inflammation and immunity has led to the development of novel treatment strategies. Several preclinical studies support the use of RT in combination with immunotherapy obtaining better local and systemic tumor control. Current ongoing studies will provide information about the optimal RT approach, but the dev...
41 CitationsSource