C McCollough
Mayo Clinic
Imaging phantomPhysicsRadiologyIterative reconstructionArtificial intelligenceNoise reductionHounsfield scaleProjection (set theory)Image resolutionScannerRadiation doseNuclear medicineMedical imagingComputer visionMathematicsRadiographyComputer scienceComputed tomographyImage qualityMedicineDosimetryImage sensorImage processing
6Publications
5H-index
277Citations
Publications 42
Newest
#1J. Montoya (Mayo Clinic)H-Index: 4
#2Andrea Ferrero (Mayo Clinic)H-Index: 8
Last. Cynthia H. McCollough (Mayo Clinic)H-Index: 76
view all 5 authors...
Purpose: To investigate the noise and spatial resolution properties of virtual non-contrast (VNC) dual-energy CT images compared to true non-contrast (TNC) images across multiple patient sizes and CT systems. Methods: Torso-shaped water phantoms with lateral widths of 25, 30, 35, 40 and 45 cm and a high resolution bar pattern phantom (Catphan CTP528) were scanned using 2nd and 3rd generation dual-source CT systems (Scanner A: Somatom Definition Flash, Scanner B: Somatom Force, Siemens Healthcare...
2 CitationsSource
#1Christopher P. Favazza (Mayo Clinic)H-Index: 24
#2Andrea Ferrero (Mayo Clinic)H-Index: 8
Last. Cynthia H. McCollough (Mayo Clinic)H-Index: 76
view all 8 authors...
Purpose: To evaluate CT low-contrast detectability at different dose levels in images reconstructed using filtered backprojection (FBP) and iterative reconstruction (IR). Methods: A validated channelized Hotelling observer (CHO) model was used to detect low contrast objects in images of a helical CT phantom (Model 061, CIRS) using an Aquilion Prime 160 scanner (Toshiba Medical Systems). Twenty-one different objects of 7 diameters (2.4, 3.2, 4.6, 6.3, 9.5, and 10 mm) and 3 contrast levels (∼10, 1...
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#1Kyle McMillan (Mayo Clinic)H-Index: 11
#2Alice E. Huang (Mayo Clinic)H-Index: 3
Last. Cynthia H. McCollough (Mayo Clinic)H-Index: 76
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Purpose: CT automatic exposure control (AEC) systems adjust tube current output in response to changes in patient attenuation. Some have interpreted this to mean that the use of AEC results in constant size-specific dose estimates (SSDE) across patient sizes. The purpose of this work was to derive the AEC parameters that yield constant SSDE across patient sizes and compare these conditions with clinical implementations of AEC. Methods: The relationship between tube current output and patient att...
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Peer-reviewed journals and conference proceedings publish hundreds of papers that describe new medical imaging algorithms, including, for example, techniques for computer-aided diagnosis or characterization, segmentation, image registration, image reconstruction, and radiomics. It is difficult, if not impossible, to fairly compare the performance of these algorithms as investigators must either use different data sets, or if using the same data, use different implementations of competing algorit...
69 CitationsSource
#1Gregory Michalak (Mayo Clinic)H-Index: 12
#2Ahmed F. Halaweish (Siemens)H-Index: 16
Last. Cynthia H. McCollough (Mayo Clinic)H-Index: 76
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Purpose: Dual energy (DE) CT can be used to characterize tissue composition. One application of DE CT is to measure electron density (ED, rho) and atomic number (Z) for use in radiation therapy treatment planning. This work evaluated the accuracy and stability of ED estimation as patient size varied for both single-energy (SE) and DE CT. Methods: An ED phantom (CIRS) and four torso-shaped water tanks (lateral widths 15, 25, 35 and 45 cm) containing 8 tissue-simulating cylinders of known ED were ...
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#1Andrea Ferrero (Mayo Clinic)H-Index: 8
#2Baiyu Chen (Mayo Clinic)H-Index: 13
Last. Cynthia H. McCollough (Mayo Clinic)H-Index: 76
view all 6 authors...
Purpose: In order to investigate novel methods to more accurately estimate the mineral composition of kidney stones using dual energy CT, it is desirable to be able to combine digital stones of known composition with actual phantom and patient scan data. In this work, we developed and validated a method to insert digital kidney stones into projection data acquired on a dual-source, dual-energy CT system. Methods: Attenuation properties of stones of different mineral composition were computed usi...
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Peer-reviewed journals and conference proceedings publish hundreds of papers that describe new medical imaging algorithms, including, for example, techniques for computer-aided diagnosis or characterization, segmentation, image registration, image reconstruction, and radiomics. It is difficult, if not impossible, to fairly compare the performance of these algorithms as investigators must either use different data sets, or if using the same data, use different implementations of competing algorit...
Source
#1Christopher D. Jaeger (Mayo Clinic)H-Index: 4
#2Andrew D. Rule (Mayo Clinic)H-Index: 45
Last. Amy E. Krambeck (Mayo Clinic)H-Index: 53
view all 11 authors...
Objective To describe the endoscopic characteristics of renal papillae in struvite stone formers (SFs). Materials and Methods From 2009 to 2014, patients undergoing percutaneous nephrolithotomy were prospectively enrolled in our study. Endoscopic analysis and biopsy of papillae were performed to demonstrate the presence and percentage surface area (SA) of Randall's plaque or ductal plug. Comparison with idiopathic calcium oxalate (CaOx) SF and non-SF controls was performed. Results We identified...
6 CitationsSource
#1Katrina N. Glazebrook (Mayo Clinic)H-Index: 21
#2Shuai Leng (Mayo Clinic)H-Index: 53
Last. C McCollough (Mayo Clinic)H-Index: 5
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Silicone implants are commonly used for both breast augmentation and breast reconstruction. With aging of the implant, the silicone envelope may become weak or may rupture. The technique of choice for evaluation of implant integrity is breast MRI; however this may be contraindicated in some patients or the cost may be prohibitive. Dual-energy CT allows determination of density and atomic number of tissue and can provide material composition information. We present a case of extracapsular implant...
8 CitationsSource
#1Chi Ma (Mayo Clinic)H-Index: 8
#2Lifeng Yu (Mayo Clinic)H-Index: 48
Last. Cynthia H. McCollough (Mayo Clinic)H-Index: 76
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Purpose: Added filtration such as tin filter has the potential to improve dose efficiency of x-ray beam in lung-cancer screening CT. However, dose efficiency with added beam filtration is highly dependent on patient attenuation level. In this phantom study, we evaluated the image quality at different tube voltages with and without added tin filter when attenuation level varies. Methods: A 30 x 20 cm anthropomorphic thorax phantom with three added extension rings were used to simulate small (S), ...
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