Eric T. Payne
Alberta Children's Hospital
Internal medicineEndocrinologyEtiologyPathologyRetrospective cohort studyIntensive care medicinePediatricsYoung adultObservational studyStatus epilepticusEpilepsyKetogenic dietEncephalopathyEpilepsy syndromesAnakinraFebrile infection related epilepsy syndromeCritically illAnesthesiaConfidence intervalRefractoryElectroencephalographyMedicineCohort
Publications 55
OBJECTIVES To characterize the pediatric super-refractory status epilepticus population by describing treatment variability in super-refractory status epilepticus patients and comparing relevant clinical characteristics, including outcomes, between super-refractory status epilepticus, and nonsuper-refractory status epilepticus patients. DESIGN Retrospective cohort study with prospectively collected data between June 2011 and January 2019. SETTING Seventeen academic hospitals in the United States...
#1Marvin H Braun (Alberta Children's Hospital)H-Index: 1
#2Eric T. Payne (Alberta Children's Hospital)H-Index: 16
Last. Colleen Curtis (U of C: University of Calgary)H-Index: 1
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#1Eric T. Payne (Alberta Children's Hospital)H-Index: 16
#2Elaine C. Wirrell (Mayo Clinic)H-Index: 63
#1Vasily A. Vakorin (SFU: Simon Fraser University)H-Index: 16
#2Dragos A. Nita (North York General Hospital)
Last. Cecil D. Hahn (U of T: University of Toronto)H-Index: 27
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Abstract Objective We aimed to test the hypothesis that computational features of the first several minutes of EEG recording can be used to estimate the risk for development of acute seizures in comatose critically-ill children. Methods In a prospective cohort of 118 comatose children, we computed features of the first five minutes of artifact-free EEG recording (spectral power, inter-regional synchronization and cross-frequency coupling) and tested if these features could help identify the 25 c...
#1Cristina Barcia Aguilar (UAM: Autonomous University of Madrid)
Last. pSERG
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Abstract Objective Evaluate the influence of weekends and holidays on time to treatment of pediatric refractory convulsive status epilepticus. Methods We performed a retrospective analysis of prospectively collected observational data from June 2011 to March 2020 of pediatric patients (1 month-21 years) with refractory status epilepticus, defined as convulsive seizures that continued after administration of at least two anti-seizure medications (ASMs), including at least one non-benzodiazepine A...
#1Sookyong Koh (Emory University)H-Index: 14
#2Elaine C. Wirrell (Mayo Clinic)H-Index: 63
Last. Eric T. Payne (Mayo Clinic)H-Index: 16
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Febrile infection-related epilepsy syndrome (FIRES) is a rare catastrophic epileptic encephalopathy that presents suddenly in otherwise normal children and young adults causing significant neurological disability, chronic epilepsy, and high rates of mortality. To suggest a therapy protocol to improve outcome of FIRES, workshops were held in conjunction with American Epilepsy Society annual meeting between 2017 and 2019. An international group of pediatric epileptologists, pediatric neurointensiv...
Objectives: The use of telemedicine use has grown exponentially as an alternative to providing care to patients with epilepsy during the pandemic. We investigated the impact of the current pandemic among children with epilepsy from two distinct pediatric epilepsy centers. We also compared perceptions among those who received telemedicine against those who did not. Methods: We developed a questionnaire and invited families followed in Freiburg, Germany and Calgary, Canada to participate during th...
#1Yi-Chen Lai (BCM: Baylor College of Medicine)H-Index: 8
#1Yi Chen Lai (BCM: Baylor College of Medicine)H-Index: 3
Last. James J. Riviello (BCM: Baylor College of Medicine)H-Index: 35
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Febrile-infection related epilepsy syndrome (FIRES) is a devastating neurological condition characterized by a febrile illness preceding new onset refractory status epilepticus (NORSE). Increasing evidence suggests innate immune dysfunction as a potential pathological mechanism. We report an international retrospective cohort of 25 children treated with anakinra, a recombinant interleukin-1 receptor antagonist, as an immunomodulator for FIRES. Anakinra was potentially safe with only one child di...
4 CitationsSource
#1Iván Sánchez Fernández (Boston Children's Hospital)H-Index: 24
#1Iván Sánchez Fernández (Boston Children's Hospital)H-Index: 5
Last. Tobias Loddenkemper (Boston Children's Hospital)H-Index: 57
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Objective: To determine whether publication of evidence on delays in time to treatment shortens time to treatment in pediatric refractory convulsive status epilepticus (rSE), we compared time to treatment before (2011-2014) and after (2015-2019) publication of evidence of delays in treatment of rSE in the pediatric status epilepticus research group (pSERG) as assessed by patient interviews and record review. Methods: We performed a retrospective analysis of a prospectively collected dataset from...
4 CitationsSource