Qiong-Hui Huang
Guangzhou University of Chinese Medicine
Internal medicineEndocrinologyProinflammatory cytokineChemistryApoptosisMyeloperoxidaseSuperoxide dismutaseOxidative stressSteatosisLiver injuryInflammationPogostemonAntioxidantMalondialdehydeGlutathione peroxidaseAnti-inflammatoryTriptolideCytochrome cReactive oxygen speciesGlutathioneMedicineVery low-density lipoproteinPharmacology
14Publications
8H-index
172Citations
Publications 14
Newest
#1Yuxuan Gan (Guangzhou University of Chinese Medicine)H-Index: 4
#2Gaoxiang Ai (Guangzhou University of Chinese Medicine)H-Index: 3
Last. Xiao-Qi Huang (Guangzhou University of Chinese Medicine)H-Index: 6
view all 12 authors...
Abstract Ethnopharmacological relevance Pogostemon cablin, commonly named “Guang-Huo-Xiang” in China, has long been renowned for its ability to dispel dampness and regulate gastrointestinal functions. Patchouli oil (P.oil), the major active fraction of Pogostemon cablin, has been traditionally used as the principal component of Chinese medicinal formulae to treat exterior syndrome and diarrhea. However, the effects of P.oil in treating 5-fluorouracil (5-FU)-induced intestinal mucositis have not ...
6 CitationsSource
#1Nan Xu (Guangzhou University of Chinese Medicine)H-Index: 5
#2Xue Wu (Guangzhou University of Chinese Medicine)H-Index: 6
Last. Yu-Hong Liu (Guangzhou University of Chinese Medicine)H-Index: 19
view all 14 authors...
Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases worldwide. Nevertheless, no first-line therapy exists. Hepatic steatosis is the earliest stage of NAFLD, which is characterized by an accumulation of hepatic lipids. Patchouli oil (PO), which is isolated from the well-known Chinese herb named Pogostemon cablin (Blanco) Benth. (Lamiaceae), inhibits hepatic lipid accumulation effectively. However, its potential ability for the treatment of NAFLD had not been...
1 CitationsSource
#1Xue Wu (Guangzhou University of Chinese Medicine)H-Index: 6
#2Nan Xu (Guangzhou University of Chinese Medicine)H-Index: 5
Last. Yu-Hong Liu (Guangzhou University of Chinese Medicine)H-Index: 19
view all 12 authors...
Nonalcoholic fatty liver disease (NAFLD) is currently the most common chronic hepatic disorder worldwide. The earliest stage of NAFLD is simple steatosis, which is characterized by the accumulation of triglycerides in hepatocytes. Inhibition of steatosis is a potential treatment for NAFLD. Patchouli alcohol (PA) is an active component of Pogostemon cablin (Blanco) Benth. (Labiatae), which is a medicinal food in Asia countries and proved to possess hepatoprotective effect. This research aimed to ...
6 CitationsSource
#1Xue Wu (Guangzhou University of Chinese Medicine)H-Index: 6
#2Qiong-Hui Huang (Guangzhou University of Chinese Medicine)H-Index: 8
Last. Yu-Hong Liu (Guangzhou University of Chinese Medicine)H-Index: 19
view all 9 authors...
Acrostichum aureum Linn., a medicinal pteridophyte growing in mangrove forests and coastal regions of tropical and subtropical areas worldwide, has been proved to possess various biological effects. However, the protective effect of Acrostichum aureum Linn. against gastric ulcer still remains unidentified. Therefore, the gastroprotective effect of the water extract of Acrostichum aureum Linn. (WEAC) was investigated in ethanol-induced gastric injury model. According to our results, pretreatment ...
10 CitationsSource
#1Yu-Hong Liu (Guangzhou University of Chinese Medicine)H-Index: 19
#2Qiong-Hui Huang (Guangzhou University of Chinese Medicine)H-Index: 8
Last. Jian-Nan Chen (Guangzhou University of Chinese Medicine)H-Index: 19
view all 10 authors...
Acetaminophen (APAP) is commonly used to relieve pain and fever in a clinical setting, but its excessive use can lead to serious hepatotoxicity. Our previous study demonstrated that polydatin (PD) can effectively attenuate D-galactose- and alcohol-induced hepatotoxicity, however, its effect on APAP-induced hepatotoxicity is still unknown. In this study, we explore the protective effect and potential mechanism of PD against APAP-induced hepatotoxicity in mice. The results indicate that PD effecti...
11 CitationsSource
#1Guosheng Lin (Guangzhou University of Chinese Medicine)H-Index: 8
#2Dandan Luo (Guangzhou University of Chinese Medicine)H-Index: 12
Last. Zi-Ren Su (Guangzhou University of Chinese Medicine)H-Index: 30
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The effect of polysaccharides isolated from Dendrobium officinale (DOP) on acetaminophen- (APAP-) induced hepatotoxicity and the underlying mechanisms involved are investigated. Male Institute of Cancer Research (ICR) mice were randomly assigned to six groups: (1) control, (2) vehicle (APAP, 230 mg/kg), (3) N-acetylcysteine (100 mg/kg), (4) 50 mg/kg DOP, (5) 100 mg/kg DOP, and (6) 200 mg/kg DOP. Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels in the serum and glutathio...
20 CitationsSource
#1Qiong-Hui Huang (Guangzhou University of Chinese Medicine)H-Index: 8
#2Xue Wu (Guangzhou University of Chinese Medicine)H-Index: 6
Last. Yu-Hong Liu (Guangzhou University of Chinese Medicine)H-Index: 19
view all 10 authors...
Correction for ‘Patchouli oil isolated from the leaves of Pogostemon cablin ameliorates ethanol-induced acute liver injury in rats via inhibition of oxidative stress and lipid accumulation’ by Qiong-Hui Huang et al., RSC Adv., 2018, 8, 24399–24410.
8 CitationsSource
#1Lan Wang (Guangzhou University of Chinese Medicine)H-Index: 1
#2Qiong-Hui Huang (Guangzhou University of Chinese Medicine)H-Index: 8
Last. Huilin Li (Guangzhou University of Chinese Medicine)H-Index: 5
view all 10 authors...
Abstract This study aimed to investigate the prophylactic effect of selenium-enriched Cordyceps militaris (CS) against triptolide-induced acute hepatotoxicity. Rats were intragastrically administrated with CS and ordinary Cordyceps militaris (CM) for 7 consecutive days prior to triptolide intoxication. Triptolide elevated levels of serum aminotransferases, total cholesterol and caused severe liver injury. However, CS remarkably inhibited the increases of these parameters and pathological damages...
5 CitationsSource
#1Xue Wu (Guangzhou University of Chinese Medicine)H-Index: 6
#2Jia-Li Liang (Guangzhou University of Chinese Medicine)H-Index: 11
Last. Qing-Feng Xie (GU: Guangzhou University)H-Index: 1
view all 7 authors...
β-patchoulene (β-PAE) is one of the essential tricyclic sesquiterpenes of patchouli oil while β-patchoulene epoxide (β-PAO) is the oxidative product of β-PAE which can only be found in the oil with...
1 CitationsSource
#1Jia-Li Liang (Guangzhou University of Chinese Medicine)H-Index: 11
#2Yao-Xing Dou (Guangzhou University of Chinese Medicine)H-Index: 9
Last. Jianping Chen (Guangzhou University of Chinese Medicine)H-Index: 15
view all 11 authors...
Abstract Patchoulene epoxide (PAO), a tricyclic sesquiterpene isolated from the long-stored patchouli oil, has been demonstrated the anti-inflammatory activity in vivo based on our previous study. However, the gastric protective effect of PAO still remains unknown. Therefore, in the present study, ethanol-induced gastric ulcer model was carried out to evaluate the anti-ulcerogenic activity of PAO and to elucidate the potential mechanisms that involves. According to our results, macroscopic exami...
17 CitationsSource