Harpreet Hyare
University College London Hospitals NHS Foundation Trust
CorrelationInternal medicineRadiologyPathologyMagnetic resonance imagingHyperintensityDiffusion MRIArtificial intelligencePsychologyIntensive care medicinePediatricsData sciencePRNPGliomaDiseaseDementiaWhite matterCognitive declineNuclear medicineGene mutationMagnetisation transferComputer scienceClinical trialMedicineComplication
36Publications
6H-index
174Citations
Publications 39
Newest
#1Rachael I. ScahillH-Index: 53
#2Paul ZeunH-Index: 3
Last. Christelle LangleyH-Index: 2
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Primary central nervous system lymphoma (PCNSL) has variable imaging appearances, which overlap with those of glioblastoma (GBM), thereby necessitating invasive tissue diagnosis. We aimed to investigate whether a rapid filtration histogram analysis of clinical MRI data supports the distinction of PCNSL from GBM. Ninety tumours (PCNSL n = 48, GBM n = 42) were analysed using pre-treatment MRI sequences (T1-weighted contrast-enhanced (T1CE), T2-weighted (T2), and apparent diffusion coefficient maps...
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#1Strachan Mackenzie (ICH: UCL Institute of Child Health)
#2Manar S. Shafat (UCL: University College London)H-Index: 10
Last. Emilie Sanchez (UCLH: University College Hospital)H-Index: 5
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#1Elwira Szychot (ICR: Institute of Cancer Research)H-Index: 4
#2Adam Youssef (GOSH: Great Ormond Street Hospital)H-Index: 2
Last. Ananth Shankar (UCLH: University College Hospital)H-Index: 14
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Abstract BACKGROUND: Diffuse midline gliomas (DMG) are aggressive brain tumours, previously known as diffuse intrinsic pontine gliomas (DIPG), with 10% overall survival (OS) at 18 months. Predicting OS will help refine treatment strategy in this patient group. MRI based texture analysis (MRTA) is novel image analysis technique that provides objective information about spatial arrangement of MRI signal intensity (heterogeneity) and has potential to be imaging biomarker. OBJECTIVES: To investigate...
3 CitationsSource
#1E.A. Lim (UCLH: University College London Hospitals NHS Foundation Trust)
#2R. Gnanadurai (UCLH: University College London Hospitals NHS Foundation Trust)
Last. Harpreet Hyare (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 6
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Patients with haematological malignancy are at increased risk of developing central nervous system (CNS) infections, which are associated with significant morbidity and mortality. Neuroimaging plays a pivotal role in the diagnostic pathway of these patients; however, layers of complexity are added to image interpretation by the heterogeneity in imaging manifestations of haematological malignancies in the CNS, overlapping imaging features of CNS infection, treatment-related parenchymal changes an...
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#1Valentina Ferrazzoli (UCLH: University College Hospital)
#2Ananth Shankar (UCLH: University College Hospital)H-Index: 14
Last. Harpreet Hyare (UCLH: University College Hospital)H-Index: 6
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#1Elwira Szychot (UCLH: University College Hospital)H-Index: 4
#2Adam Youssef (GOSH: Great Ormond Street Hospital)H-Index: 2
Last. Kshitij Mankad (GOSH: Great Ormond Street Hospital)H-Index: 21
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#1Ananth Shankar (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 14
#2Jamshed Bomanji (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 12
Last. Harpreet Hyare (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 6
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(1) Background: Standard magnetic resonance imaging (MRI) remains the gold standard for brain tumour imaging in paediatric and teenage and young adult (TYA) patients. Combining positron emission tomography (PET) with MRI offers an opportunity to improve diagnostic accuracy. (2) Method: Our single-centre experience of 18F-fluorocholine (FCho) and 18fluoro-L-phenylalanine (FDOPA) PET–MRI in paediatric/TYA neuro-oncology patients is presented. (3) Results: Hybrid PET–MRI shows promise in the evalua...
1 CitationsSource
#1Ferras Alwan (UCLH: University College Hospital)H-Index: 4
#2Dina Mahdi (UCLH: University College Hospital)H-Index: 1
Last. Marie Scully (UCLH: University College Hospital)H-Index: 37
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Thrombotic thrombocytopenic purpura (TTP) is a rare thrombomicroangiopathy caused by deficiency of ADAMTS13. Acute neurological involvement is well described, but its long-term impact requires evaluation. One-hundred thirty-one patients, following an acute TTP event, with severe headache or neurological symptoms had a cerebral MRI. Fifty-six percent had abnormal imaging, more commonly in patients with neurological symptoms than headaches only (80% vs. 18%, P < 0·0001). In remission, 27% (n = 35)...
2 CitationsSource
#1Jennifer A. Foley (UCL Institute of Neurology)H-Index: 10
Last. Diana CaineH-Index: 6
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Abstract Visual imagery, like vision as such, is widely thought to be supported by two distinct and dissociable processing streams, dedicated to object representation and spatial analysis respectively. However, this simple dichotomy has been contested, with recent studies suggesting that impairments in perception-for-action and visuo-spatial imagery may reflect a more general deficit in space-based attention. Although previous studies have revealed the impact of brain damage on artistic expressi...
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