Jéssica Thaís do Prado Silva
Federal University of Technology - Paraná
Detection limitBiophysicsXanthophyllSolubilityNanoparticleMinimum inhibitory concentrationNutraceuticalEnzymeBioavailabilityChemistryMaterials scienceIn vitroNanocapsulesIn vivoEx vivoUltravioletCurcumaCurcuminLuteinAcetylcholinesteraseCarotenoidBiological propertyIn silico dockingIn vivo testsFood scienceIn vitro toxicologyChromatographyAntimicrobialBiochemistryUltraviolet visible spectroscopyPreservative
5Publications
4H-index
86Citations
Publications 5
Newest
#1Cristiane Grella Miranda (UTFPR: Federal University of Technology - Paraná)H-Index: 3
#2Priscila Dayane Freitas dos Santos (UTFPR: Federal University of Technology - Paraná)H-Index: 2
Last. Odinei Hess Gonçalves (IPN: Instituto Politécnico Nacional)H-Index: 16
view all 8 authors...
Abstract Lutein is a bioactive found in dark leafy vegetables that may be used as a nutraceutical agent in foodstuff and an inhibitor of key enzymes of the human body such as those involved in the cholinergic system. However, its high hydrophobicity leads to low bioavailability and must be overcome if lutein is to be added in foods. The objective of this study was to evaluate the influence of nanoencapsulated lutein in the activity of the acetylcholinesterase enzyme. The in vitro study was carri...
5 CitationsSource
#1Anderson Clayton da Silva (UTFPR: Federal University of Technology - Paraná)H-Index: 3
#2Priscila Dayane de Freitas Santos (UTFPR: Federal University of Technology - Paraná)H-Index: 4
Last. Odinei Hess Gonçalves (UTFPR: Federal University of Technology - Paraná)H-Index: 16
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Abstract Background Curcumin is a yellow-orange, hydrophobic compound extracted from Curcuma longa and widely used by oriental cultures. It displays numerous biological activities and shows antimicrobial activity against both Gram-positive and Gram-negative bacteria, as well as yeasts and molds. However, its low water solubility decreases its bioavailability and hinders its industrial use. Curcumin may be modified by micro/nanoencapsulation or nanonization (transformation in nanometric crystals)...
45 CitationsSource
Last. Fernanda Vitória LeimannH-Index: 15
view all 9 authors...
A quantidade de residuos gerados durante o beneficiamento do cafe no Brasil (principalmente casca) representa aproximadamente 50% da producao. Visando diminuir este problema, o objetivo deste trabalho foi obter diferentes extratos das cascas de cafe, avaliar sua composicao e atividade antimicrobiana. Utilizando extracoes por Soxhlet, com solventes de diferentes polaridades e seletividades e analisando estes extratos por Cromatografia Gasosa acoplada a Espectrometria de Massas e Espectroscopia de...
5 CitationsSource
#1Jéssica Thaís do Prado Silva (UTFPR: Federal University of Technology - Paraná)H-Index: 4
#2Anderson Clayton da Silva (UTFPR: Federal University of Technology - Paraná)H-Index: 3
Last. Odinei Hess Gonçalves (UTFPR: Federal University of Technology - Paraná)H-Index: 16
view all 10 authors...
Abstract Lutein is a carotenoid presenting known anti-inflammatory and antioxidant properties. Lutein-rich diets have been associated with neurological improvement as well as reduction of the risk of vision loss due to Age-Related Macular Degeneration (AMD). Micro and nanoencapsulation have demonstrated to be effective techniques in protecting lutein against degradation and also in improving its bioavailability. However, actual lutein concentration inside the capsules and encapsulation efficienc...
14 CitationsSource
#1Jéssica Thaís do Prado Silva (UTFPR: Federal University of Technology - Paraná)H-Index: 4
#2Julia Maria Tonin Geiss (UTFPR: Federal University of Technology - Paraná)H-Index: 2
Last. Odinei Hess Gonçalves (UTFPR: Federal University of Technology - Paraná)H-Index: 16
view all 10 authors...
Abstract Lutein is a xanthophyll carotenoid widely known by its biological properties and low toxicity. When located in the brain, lutein may inhibit damage mechanisms, acting in neural cells maintenance. However, this carotenoid is very sensitive to external agents such as heat, light, pH and oxidation, besides presenting low absorption in gastrointestinal tract due its low solubility in water. Encapsulation procedures have shown promising results to increase lutein stability and bioavailabilit...
26 CitationsSource