Kevin M. Bradley
Cardiff University
CancerInternal medicineRadiologyPET-CTSurgeryPathologyOncologyTomographyNeuroscienceStage (cooking)Positron emission tomographyChemotherapyFluorodeoxyglucoseNeoadjuvant therapyEsophageal cancerNuclear medicineFdg pet ctComputer scienceImage qualityMedicine
Publications 128
#1Abolfazl Mehranian (University of Oxford)H-Index: 1
#2Scott David Wollenweber (GE Healthcare)H-Index: 16
Last. Daniel R. McGowan (University of Oxford)H-Index: 13
view all 10 authors...
To enhance the image quality of oncology [18F]-FDG PET scans acquired in shorter times and reconstructed by faster algorithms using deep neural networks. List-mode data from 277 [18F]-FDG PET/CT scans, from six centres using GE Discovery PET/CT scanners, were split into ¾-, ½- and ¼-duration scans. Full-duration datasets were reconstructed using the convergent block sequential regularised expectation maximisation (BSREM) algorithm. Short-duration datasets were reconstructed with the faster OSEM ...
1 CitationsSource
#1Kieran Foley (Cardiff University)H-Index: 9
#2Anita Lavery ('QUB': Queen's University Belfast)H-Index: 3
Last. Richard C. Turkington ('QUB': Queen's University Belfast)H-Index: 11
view all 8 authors...
18F-fluorodeoxyglucose PET-CT may guide treatment decisions in patients with oesophageal adenocarcinoma (OAC). This study evaluated the added value of maximum standardised uptake value (SUVmax) to a novel DNA-damage immune response (DDIR) assay to improve pathological response prediction. The diagnostic accuracy of PET response and the prognostic significance of PET metrics for recurrence-free survival (RFS) and overall survival (OS) were assessed. This was a retrospective, single-centre study o...
#1Kevin M. Bradley (University Hospital of Wales)H-Index: 28
#2Timothy Deller (GE Healthcare)H-Index: 11
Last. Daniel R. McGowan (University of Oxford)H-Index: 13
view all 5 authors...
#1Kevin M. Bradley (University of Oxford)H-Index: 28
#2Timothy Deller (GE Healthcare)H-Index: 11
Last. Daniel R. McGowan (University of Oxford)H-Index: 13
view all 5 authors...
#1Nicolas Aide (French Institute of Health and Medical Research)H-Index: 28
#2Charline Lasnon (French Institute of Health and Medical Research)H-Index: 12
Last. Daniel R. McGowan (Churchill Hospital)H-Index: 13
view all 11 authors...
#1Kieran G Foley (Royal Glamorgan Hospital)
Last. Elizabeth C Smyth (Cambridge University Hospitals NHS Foundation Trust)H-Index: 7
view all 6 authors...
PURPOSE Only 25% of oesophageal adenocarcinoma (OAC) patients have a pathological response to neo-adjuvant therapy (NAT) before oesophagectomy. Early response assessment using PET imaging may help guide management of these patients. We performed a systematic review and meta-analysis to synthesise the evidence detailing response rate and diagnostic accuracy of early PET-CT assessment. METHODS We systematically searched several databases including MEDLINE and Embase. Studies with mixed cohorts of ...
#1Matthew David Walker (University of Oxford)H-Index: 1
#2Kevin M. BradleyH-Index: 28
Last. Daniel R. McGowan (University of Oxford)H-Index: 13
view all 3 authors...
REPLY: Dr. Kesner’s letter regarding our recent publication ([1][1]) raises several useful points. We wholeheartedly agree that data-driven gating is an important innovation. Indeed, the launch of a commercial implementation provides an opportunity for celebration of this success and for
#1Dario Arnaldi (UniGe: University of Genoa)H-Index: 24
#2Andrea ChincariniH-Index: 103
Last. Flavio Nobili (UniGe: University of Genoa)H-Index: 69
view all 33 authors...
This is an international multicentre study aimed at evaluating the combined value of dopaminergic neuroimaging and clinical features in predicting future phenoconversion of idiopathic REM sleep behaviour (iRBD) subjects to overt synucleinopathy. Nine centres sent 123I-FP-CIT-SPECT data of 344 iRBD patients and 256 controls for centralized analysis. 123I-FP-CIT-SPECT images were semiquantified using DaTQUANTTM, obtaining putamen and caudate specific to non-displaceable binding ratios (SBRs). The ...
7 CitationsSource
#1Matthew David Walker (University of Oxford)H-Index: 1
#2Andrew J. Morgan (University of Oxford)H-Index: 2
Last. Daniel R. McGowan (University of Oxford)H-Index: 13
view all 4 authors...
A data-driven method for respiratory gating in PET has recently been commercially developed. We sought to compare the performance of the algorithm to an external, device-based system for oncological [(18)F]-FDG PET/CT imaging. Methods: 144 whole-body [(18)F]-FDG PET/CT examinations were acquired using a Discovery D690 or D710 PET/CT scanner (GE Healthcare), with a respiratory gating waveform recorded by an external, device based respiratory gating system. In each examination, two of the bed posi...
10 CitationsSource
#1Afolarin Otunla (University of Oxford)H-Index: 1
view all 2 authors...
Pilomatricoma, also known as calcifying epithelioma of Malherbe, is a rare skin tumor originating from the hair follicle matrix. We report a case of pilomatricoma in a 50-year-old woman, presenting as a rapidly growing pretibial mass. Malignant pilomatricoma is associated with potentially fatal metastases and are clinically and histologically indistinguishable from benign pilomatricoma. Thus, an 18F-fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG PET/CT) scan was req...