Satyendra K. Singh
Michigan State University
Internal medicineGenotypePathologyCase-control studyVirologyChemistryImmunologyInflammationTaeniaAsymptomaticCysticercosisCytokineTaeniasisVancomycinDiseaseStaphylococcus aureusPhosgene oximeNeurocysticercosisPathogenesisTaenia soliumCancer researchMedicineBiologyImmune systemMicrobiologyPharmacology
34Publications
9H-index
180Citations
Publications 29
Newest
#1Satyendra K. Singh (MSU: Michigan State University)H-Index: 9
#2Dinesh G Goswami (Anschutz Medical Campus)H-Index: 8
Last. Kathryn PateH-Index: 1
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Abstract null null With a possibility for the use of chemical weapons in battlefield or in terrorist activities, effective therapies against the devastating ocular injuries, from their exposure, are needed. Oxygen plays a vital role in ocular tissue preservation and wound repair. We tested the efficacy of supersaturated oxygen emulsion (SSOE) in reducing ex vivo corneal and keratocyte injury from chloropicrin (CP). CP, currently used as a pesticide, is a chemical threat agent like the vesicating...
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#6Neera Tewari-Singh (MSU: Michigan State University)H-Index: 1
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#1Satyendra K. Singh (MSU: Michigan State University)H-Index: 9
#1Satyendra Kumar Singh (MSU: Michigan State University)
Last. Neera Tewari-Singh (MSU: Michigan State University)H-Index: 1
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Highly toxic industrial chemicals that are widely accessible, and hazardous chemicals like phosgene oxime (CX) that can be easily synthesized, pose a serious threat as potential chemical weapons. In addition, their accidental release can lead to chemical emergencies and mass casualties. CX, an urticant, or nettle agent, grouped with vesicating agents, causes instant pain, injury and systemic effects, which can lead to mortality. With faster cutaneous penetration, corrosive properties, and more p...
1 CitationsSource
#1Swati Sharma (MSU: Michigan State University)
#2Joshua A. Klein (MSU: Michigan State University)H-Index: 1
Last. Neera Tewari-Singh (MSU: Michigan State University)H-Index: 1
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#1Rashmi RayH-Index: 5
#2Nitish JangdeH-Index: 1
Last. Vivek RaiH-Index: 20
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#1Rashmi RayH-Index: 5
#2Nitish Jangde (Manipal University)H-Index: 1
Last. Vivek RaiH-Index: 20
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BACKGROUND Receptor for advanced glycation end products (RAGE) is a multi-ligand transmembrane receptor of the immunoglobulin superfamily. Lysophosphatidic acid (LPA) is a ligand for RAGE and is involved in physiological and pathophysiological conditions including cancer. However, RAGE-LPA axis is unexplored in lung and mammary cancer. METHODS RAGE was silenced in A549, MDA MB-231 and MCF7 using RAGE shRNA. For in vitro tumorigenesis, we performed wound healing, colony formation, cell proliferat...
1 CitationsSource
#1Satyendra K. SinghH-Index: 9
#2Sunita Sinha (Manipal University)H-Index: 1
Last. Vivek RaiH-Index: 20
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Non-muscle myosin IIA heavy chain (MYH9) has been implicated in many physiological and pathological functions including cell adhesion, polarity, motility to cancer. However, its role in melanoma remains unexplored. The aim of our study was to evaluate the role of MYH9 in melanoma tumor development and metastasis and further to find out the potential underlying mechanisms. In this study, we evaluated the in vitro migratory and invasive properties and in vivo tumor development and metastasis in C5...
3 CitationsSource
#1Satyendra K. Singh (MSU: Michigan State University)H-Index: 9
#1Satyendra Kumar Singh (MSU: Michigan State University)
Last. Neera Tewari-Singh (MSU: Michigan State University)H-Index: 1
view all 6 authors...
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#1Joshua A. Klein (MSU: Michigan State University)H-Index: 1
#2Satyendra K. Singh (MSU: Michigan State University)H-Index: 9
Last. Neera Tewari-Singh (MSU: Michigan State University)H-Index: 1
view all 8 authors...
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#1Nitish Jangde (Manipal University)H-Index: 1
#2Rashmi Ray (Manipal University)H-Index: 5
Last. Vivek RaiH-Index: 20
view all 8 authors...
Abstract Receptor for Advanced Glycation End product (RAGE) is a multiligand receptor implicated in diverse pathological conditions such as diabetes, atherosclerosis, cancer and neural diseases. Extracellular, RAGE consists of V, C1 and C2 domains. Here, we show RAGE exists as a monomer in equilibrium with a fraction of a covalently linked dimer of monomers via its V domain through cysteine. In order to understand the functional implication of this dimer, we examined the binding capacity and fun...
3 CitationsSource