Kristin J. Redmond
Johns Hopkins University School of Medicine
Internal medicineRadiologySurgeryMagnetic resonance imagingOncologyRetrospective cohort studySystemic therapyProspective cohort studyMedical physicsRadiation treatment planningBrain metastasisMetastasisMEDLINERadiosurgerySpinal metastasesToxicityStereotactic body radiation therapyNuclear medicineStereotactic body radiotherapyProportional hazards modelRadiation therapyMedicine
140Publications
21H-index
1,560Citations
Publications 172
Newest
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#1Yilin Cao (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 3
#2Hanbo Chen (Sunnybrook Health Sciences Centre)H-Index: 9
Last. Ian Poon (Sunnybrook Health Sciences Centre)H-Index: 23
view all 12 authors...
PURPOSE/OBJECTIVE(S) The definition of oligometastatic (OM) disease has largely focused on the number of metastatic lesions. Here, we investigate the total volumetric burden of metastases at initial OM presentation as an independent prognostic factor for distant progression free survival (DPFS), widespread progression (WSP, i.e., > 5 new lesions), and overall survival (OS) in patients treated with SBRT. MATERIALS/METHODS Patients with oligometastatic cancer treated with SBRT at 6 international i...
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Purpose/Objective(s) null In recent years, stereotactic body radiotherapy (SBRT) has emerged as an effective local treatment for oligometastatic cancers. However, it has been suggested that colorectal cancers may represent a more radioresistant histology, even to the high doses used in SBRT. Here, we report local recurrence rates, progression free-survival, and overall survival of patients with oligometastatic CRC treated with SBRT using a large multi-institutional data-base. null null null Mate...
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#1Hanbo Chen (Sunnybrook Health Sciences Centre)H-Index: 9
#2Eshetu G. Atenafu (Princess Margaret Cancer Centre)H-Index: 38
Last. Umberto Ricardi (UNITO: University of Turin)H-Index: 54
view all 12 authors...
Purpose/Objective(s) null Stereotactic body radiation therapy (SBRT) is an increasingly important modality in the management of patients with oligometastatic disease (OMD). Though prospective clinical trials have demonstrated the benefits of SBRT in a variety of oligometastatic settings, there is currently limited data to guide patient selection and provide long-term prognostic information for OMD patients. The purpose of this study was to create a clinical prognostic model for overall survival ...
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#1Xuguang Chen (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 2
#2M.C. LeCompte (JHUSOM: Johns Hopkins University School of Medicine)
Last. Kristin J. Redmond (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 21
view all 7 authors...
PURPOSE/OBJECTIVE(S) Stereotactic body radiotherapy (SBRT) is increasingly utilized for the treatment of spine metastasis. Although consensus guidelines for spine SBRT target delineation have been published, data regarding their impact on patient outcomes are limited. The goal of this study is to analyze predictive factors for long-term local control (LC) in a large, mature series. MATERIALS/METHODS Patients with de novo metastasis of the spine treated at an academic institution between 2009 and...
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#1Atallah Baydoun (Case Western Reserve University)H-Index: 9
#2Hanbo Chen (Sunnybrook Health Sciences Centre)H-Index: 9
Last. Umberto Ricardi (UNITO: University of Turin)H-Index: 54
view all 12 authors...
Purpose/objective(s) null Stereotactic body radiation therapy (SBRT) has emerged as an effective treatment approach in oligometastatic patients with adrenal gland metastases (AGM). Nevertheless, most of the literature reporting SBRT outcomes for AGM comes from published single institutional experience, and no specific guidelines are yet established to guide patients' inclusion and dosimetric planning. null Materials/methods null The Consortium for Oligometastases Research (CORE) is currently the...
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#1Zain A. Husain (Sunnybrook Health Sciences Centre)H-Index: 21
#2Hanbo Chen (Sunnybrook Health Sciences Centre)H-Index: 9
Last. Arjun Sahgal (Sunnybrook Health Sciences Centre)H-Index: 68
view all 11 authors...
PURPOSE/OBJECTIVE(S) Treatment of oligometastatic disease with SBRT has shown the potential to improve disease control and survival in trials largely focused on lung and prostate cancer. Outcomes in other sites, such as head and neck cancers (HNC) are poorly defined. Here we report the results of a multi-institutional cohort of oligometastatic HNC patients receiving SBRT. MATERIALS/METHODS Data on HNC patients treated between 2008 and 2016 was extracted from an international consortium of six hi...
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#1Timothy A. Lin (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 8
#2C. Siu (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 1
Last. Lawrence Kleinberg (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 48
view all 7 authors...
PURPOSE/OBJECTIVE(S) The optimal timing of interval MRI surveillance following stereotactic radiosurgery (SRS) to detect most new lesions while asymptomatic and treatable by additional radiosurgery is unknown. As frequent MRI follow-up is an important patient burden and contributor to cost of care for brain metastases, we aimed to characterize the utility of early initial post-treatment MRI brain surveillance and to identify patient characteristics that might be used to risk-stratify patients wh...
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#7Julie R. Brahmer (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 17
Purpose/Objective(s) null Radiotherapy, especially high-dose radiation in the form of stereotactic body radiotherapy (SBRT), may stimulate the therapeutic effect of immune checkpoint inhibitors (ICIs). Both SBRT and ICIs play an increasingly important role in the management of spine metastasis. We hypothesize that SBRT and ICI may act synergistically to improve the outcomes of patients with spine metastasis. null null null Materials/Methods null We retrospectively reviewed patients with spine me...
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#1Zach Pennington (Mayo Clinic)H-Index: 3
#2Sutipat Pairojboriboon (JHUSOM: Johns Hopkins University School of Medicine)
Last. Sheng Fu L. Lo (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 16
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BACKGROUND CONTEXT With improvements in adjuvant radiotherapy and minimally invasive surgical techniques, separation surgery has become the default surgical intervention for spine metastases at many centers. However, it is unclear if there is clinical benefit from anterior column resection in addition to simple epidural debulking prior to stereotactic body radiotherapy (SBRT). PURPOSE To examine the effect of anterior column debulking versus epidural disease resection alone in the local control ...
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