Shu-Jun Sun
Graduate School USA
QT intervalCaspase 3Traditional Chinese medicineApoptosisAdverse effectIn vitroBone marrow suppressionAcute promyelocytic leukemiaTransaminaseCreatinineLow-dose chemotherapyPsoralenCaspase 8Flow cytometryCell growthSignal transductionMedicineCell cultureMechanism (biology)Gastroenterology
Publications 4
Objective To study the regulatory effects of psoralen (PSO) plus ultraviolet A (UVA), which is PUVA, on cell apoptosis of human leukemia cell line NB4 and signal pathway of cell apoptosis. Methods Human leukemia cell line NB4 was cultured in vitro. The NB4 cells were treated with PSO extracted from Chinese medicine psoralea fruits at different concentrations (0, 5, 10, 20 and 40 μL) plus UVA of wave length 360 nm at different irradiation time points (0 and 5 min). The apoptosis ratio was detecte...
#1Yang XiangH-Index: 2
#2Xiao-Bo WangH-Index: 1
Last. Shi-Lin HuangH-Index: 2
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OBJECTIVE: To report the results of curative and adverse effects of compound huangdai tablet (CHDT) as induction therapy for 193 patients with acute promyelocytic leukemia (APL). METHODS: CHDT was administered 1.25 g orally three times a day after meal for three days, then the dosage was gradually increased to 7.5 g/d. RESULTS: One hundred and ninety-three patients achieved complete remission (CR), 78.8% of whom in 30 to 60 days with an average time of 44.3 d. No serious infection, bleeding or D...
5 Citations
#1Shu-Jun SunH-Index: 2
#2Yang XiangH-Index: 2
Last. Shi-Lin HuangH-Index: 2
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The progress in the research of pharmacological mechanism of anti-fibrosis traditional Chinese drugs and the effective components is summarized.It's demonstrated by pharmacological experiments that anti-fibrosis traditional Chinese drugs can inhibit the cell proliferation,regulate the cytokines and ECM,and intervente in the signal transduction.
2 Citations
#1Shi-lin HuangH-Index: 3
#2Shu-Jun SunH-Index: 2
Last. Fu-Ying HanH-Index: 1
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1 CitationsSource