Ashwin Singh Parihar
Post Graduate Institute of Medical Education and Research
Internal medicineRadiologyPET-CTPathologyGlutamate carboxypeptidase IIPositron emission tomographyProstateCarcinomaPresentation (obstetrics)LungDiseaseMalignancyThyroid cancerScintigraphyDOTAProstate cancerPositron Emission Tomography-Computed TomographyNuclear medicineTreatment responseIn patientFdg pet ctThyroidComputed tomographyHistopathologyMedicineSomatostatin receptor
60Publications
5H-index
127Citations
Publications 63
Newest
#1Sonya Youngju Park (St Mary's Hospital)
Last. Erik Mittra (OHSU: Oregon Health & Science University)H-Index: 5
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A new era of precision diagnostics and therapy for patients with neuroendocrine neoplasms began with the approval of somatostatin receptor (SSTR) radiopharmaceuticals for positron emission tomography (PET) imaging followed by peptide receptor radionuclide therapy (PRRT). With the transition from SSTR-based gamma scintigraphy to PET, the higher sensitivity of the latter raised questions regarding the direct application of the planar scintigraphy-based Krenning score for PRRT eligibility. Also, to...
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#1Ashwin Singh Parihar (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 5
#2Rajender Kumar (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 6
Last. Bhagwant Rai Mittal (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 27
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2000 Objectives: IgG4 related disease (IgG4-RD) is a rare, multi-organ involving fibro-inflammatory disease that is categorized as an orphan disease. It is referred to as the great mimicker because of the diverse range of tissue involvement and widely varying clinical presentation, often overlapping with those of common malignancies. Accurate identification of IgG4-RD is vital as it has a very favorable response to medical treatment with steroids. 18F-FDG PET/CT is a valuable modality in the ass...
#1Baljinder Singh (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 13
#2Sarika SharmaH-Index: 12
Last. Shrawan Kumar SinghH-Index: 31
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Objective The present study was performed for head-to-head comparison between 68Ga-prostate-specific membrane antigen (PSMA) PET/computed tomography (CT) and 99mTc-PSMA whole-body and regional single-photon emission computed tomography (SPECT)/CT for the detection of prostate cancer metastases. Methods Ten patients with metastatic prostate cancer underwent 99mTc-PSMA whole-body scan after intravenous injection of 230-330 MBq 99mTc-PSMA. Anterior and posterior whole-body images were acquired at 1...
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#1Swayamjeet Satapathy (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 3
Last. Bhagwant Rai MittalH-Index: 27
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ABSTRACT Radioligand therapy with 177Lu-PSMA-617 has emerged as a promising treatment modality for patients with mCRPC (metastatic castration resistant prostate cancer). However, genomic defects in DNA damage repair mechanisms have been proposed to affect the radiosensitivity of prostate cancers. Patients harboring such deleterious mutations are, thus, unlikely to respond to 177Lu-PSMA-617 alone and would need a more tailored therapeutic approach. We report the case of a 68-year-old man with ATM...
1 CitationsSource
#1Ashwin Singh Parihar (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 5
#2Kunal Ramesh Chandekar (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 1
Last. Bhagwant Rai Mittal (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 3
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We present a case of metastatic prostate cancer with rare metastases involving the brain and orbit, in addition to liver, skeletal and nodal metastases. The patient had undergone prior hormonal therapy and chemotherapy and had disease progression despite 2 cycles of 177Lu-Prostate specific membrane antigen (177Lu-PSMA) based radioligand therapy. He had a partial response after 2 cycles of 225Ac-PSMA based targeted alpha therapy, as demonstrated on the 68Ga-PSMA PET/CT study. However, the patient...
3 CitationsSource
#2Ashwin Singh Parihar (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 5
#3Sanjay Kumar Bhadada (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 25
Last. Bhagwant Rai Mittal (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 27
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Tumoral calcinosis is a rare entity presenting with periarticular calcium deposits, leading to multiple swellings and biochemical hyperphosphatemia and normocalcemia. Skeletal scintigraphy in these cases is helpful by providing a whole-body survey and delineating the common multifocality of this entity. We present the case of a 16-year-old boy with multiple swellings around the knee and elbow joints, having developed over 4 years and diagnosed as tumor calcinosis.
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#2Garima DabasH-Index: 4
Last. Bhagwant Rai MittalH-Index: 27
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#1Ashwin Singh Parihar (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 5
#2Apurva Sood (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 7
Last. Bhagwant Rai Mittal (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 27
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We present the case of a 60-year-old man with metastatic neuroendocrine tumor of the ileum following ileal resection, being evaluated for 177Lu-based peptide receptor radionuclide therapy. 68Ga-DOTANOC PET/CT showed focal increased tracer uptake in the scrotal region without any morphologic changes on the corresponding CT images. Similar increased tracer uptake was seen on post-therapy whole-body imaging following 177Lu-DOTATATE therapy. An USG guided FNA revealed no malignant cells on cytopatho...
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#1Ashwin Singh Parihar (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 5
#2Gurjeet Kaur (PGIMER: Post Graduate Institute of Medical Education and Research)
Last. Bhagwant Rai MittalH-Index: 27
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124 Objectives: Multiple Endocrine Neoplasia (MEN) comprises several distinct syndromes, constituting endocrine tumors as well as several non-endocrine pathologies. MEN 1 (MEN 1 gene mutation) primarily constitutes multi-gland parathyroid disease, pituitary adenoma and pancreatic tumors. MEN 2A (RET gene mutation) comprises of medullary thyroid carcinoma, pheochromocytoma and multi-gland parathyroid disease, while MEN 2B (RET gene mutation), additionally has mucosal neuromas. Multiple individual...
#1Bhagwant Rai MittalH-Index: 27
#2Ashwin Singh Parihar (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 5
Last. Anil Bhansali (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 59
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130 Objectives: Ectopic Cushing syndrome (ECS), accounting for ~10% of all cases of Cushing syndrome, is caused by ectopic secretion of Adrenocorticotropic hormone (ACTH). After excluding pituitary and adrenal causes, a probable tumor secreting ACTH has to be looked for. Conventional imaging such as USG, HRCT Chest, CT abdomen and MRI are frequently employed for the workup of these patients. Metabolic derangements, such as hypokalemia, metabolic alkalosis and raised ACTH not responding to dexame...