Xiazhi Zhang
Jinan University
Surface modificationPolyesterComposite materialProinflammatory cytokineNanotechnologyPolymer blendMaterials scienceScanning electron microscopeHalloysiteBiocompatibilityNanotubeDrug deliveryChemical engineeringAttenuated total reflectionFiberPolymerContact anglePolyhydroxyalkanoatesAdhesionNanofiber
5Publications
4H-index
84Citations
Publications 5
Newest
#1Xiaoyan Liu (JNU: Jinan University)H-Index: 5
#2Xiazhi Zhang (JNU: Jinan University)H-Index: 4
Last. Changren Zhou (JNU: Jinan University)H-Index: 34
view all 6 authors...
AbstractElectrospinning has been used to fabricate random and aligned poly (L-lactic acid) (PLLA) fibers with three kinds of diameter under optimal conditions. The main purpose of this paper was to investigate the influence of the diameter and orientation of fibers on the bioactivity of endothelial cells, especially on the inflammatory cytokines expression. The morphology of electrospun fibers and the cells on the fibers after 3 and 6 days culture were observed by scanning electron microscopy. A...
4 CitationsSource
#1Yu Ke (JNU: Jinan University)H-Index: 13
#2Xiazhi Zhang (JNU: Jinan University)H-Index: 4
Last. Gang Wu (SCUT: South China University of Technology)H-Index: 18
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Abstract Polyhydroxyalkanoates (PHAs) are a class of natural polyesters as carbon and energy reserves by > 300 species of microorganisms. They are fully biodegradable, biocompatible and piezoelectric biopolymers that have attracted much attention recently as the biomaterial of choice for medical applications. However, the toughness, processability and hydrophilicity of PHAs need to tune to expand their applications as tissue engineering scaffolds or drug delivery systems. Reactive polymer blendi...
27 CitationsSource
#1Keke Wu (JNU: Jinan University)H-Index: 9
#2Xiazhi Zhang (JNU: Jinan University)H-Index: 4
Last. Changren Zhou (JNU: Jinan University)H-Index: 34
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Electrospun poly(l-lactic acid) (PLLA) nanofiber mats were successfully modified by deposition of multilayers with chitosan (CS), heparin (Hep) and graphene oxide (GO) through electrostatic layer-by-layer (LBL) self-assembly method. In this study, the surface properties of PLLA nanofiber mats before and after modification were investigated via scanning electron microscope (SEM), atomic force microscopy (AFM), attenuated total reflectance fourier transformation infrared spectroscopy (ATR-FTIR), X...
11 CitationsSource
#1Wufeng Yang (JNU: Jinan University)H-Index: 5
#2Xiazhi Zhang (JNU: Jinan University)H-Index: 4
Last. Changren Zhou (JNU: Jinan University)H-Index: 34
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Abstract A simple but straightforward approach was reported to prepare fiber mats modified with fibronectin (Fn) protein for endothelial cells activity study. Based on the self-polymerization and strong adhesion feature of dopamine, poly L-Lactic acid (PLLA) fibers mat was modified via simply immersing them into dopamine solution for 16 h. Subsequently, Fn was immobilized onto the fiber mats surface by the coupling reactive polydopamine (PDA) layer and Fn. Attenuated total reflectance Fourier tr...
13 CitationsSource
#1Xiazhi Zhang (JNU: Jinan University)H-Index: 4
#2Rui Guo (JNU: Jinan University)H-Index: 19
Last. Yaowu Zhao (JNU: Jinan University)H-Index: 1
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In this study, poly(l-lactide) (PLLA)/halloysite nanotube (HNT) electrospun mats were prepared as a dual-drug delivery system. HNTs were used to encapsulate polymyxin B sulphate (a hydrophilic drug...
27 CitationsSource