Mohammad Ali Barghi
University of Tehran
ParticleNuclear chemistryDissolution testingDeposition (aerosol physics)Factorial experimentNanotechnologyMoistureNanocarriersLiposomeChemistryParticle sizeMaterials scienceWater contentLeucineItraconazoleDry-powder inhalerLactoseAerosolSpray dryingChitosanEthanolDipalmitoylphosphatidylcholinePolymeric micellesPharmacology toxicologyDifferential scanning calorimetryChemical engineeringChromatographyCrystallinityPEG ratioMetalMedicineDivalentAerosolizationDissolutionDispersion (chemistry)
5Publications
3H-index
41Citations
Publications 5
Newest
#1Ahmadreza Barazesh (Tehran University of Medical Sciences)H-Index: 1
#2Kambiz Gilani (Tehran University of Medical Sciences)H-Index: 26
Last. Mohammad Ali Barghi (UT: University of Tehran)H-Index: 3
view all 4 authors...
Purpose Metal salts are used in formulation of dry powder inhalers (DPIs) for different purposes. Recently the role of these salts in production of small, dense but highly dispersible particles has emerged. In this study the effect of some such salts on dispersibility and respirability of spray dried levofloxacin formulations was evaluated in normal and reduced inhalation air flow or by increasing powder filling in capsules.
1 CitationsSource
#1Ahmadreza Barazesh (Tehran University of Medical Sciences)H-Index: 1
#2Kambiz Gilani (Tehran University of Medical Sciences)H-Index: 26
Last. Mohammad Ali Barghi (UT: University of Tehran)H-Index: 3
view all 4 authors...
Abstract The aim of this study was to evaluate the effect of leucine at different pH values preferred for inhalation on particle characteristics and aerosolization performance of spray dried carrier-free formulations of levofloxacin. A full factorial design was applied to optimize the formulation containing levofloxacin with or without leucine in different pH values and the optimum condition was determined. Particle size and morphology, crystallinity state, electrostatic charge and surface compo...
10 CitationsSource
#1Zahra Daman (Tehran University of Medical Sciences)H-Index: 7
#2Kambiz Gilani (Tehran University of Medical Sciences)H-Index: 26
Last. Mohammad Ali Barghi (UT: University of Tehran)H-Index: 3
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Background The aim of this work was to develop dry powder inhaler (DPI) formulations of salbutamol sulfate (SS) by the aid of solid lipid microparticles (SLmPs), composed of biocompatible phospholipids or cholesterol.
7 CitationsSource
#1Kambiz Gilani (Tehran University of Medical Sciences)H-Index: 26
#2Zahra Daman (Tehran University of Medical Sciences)H-Index: 7
Last. Mohammad Ali Barghi (UT: University of Tehran)H-Index: 3
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This study investigated various solid dispersions of itraconazole with different carrier blends to enhance its dissolution. HPMC E5, HPMC E15, PEG 20000 and TPGS 1000 were used to construct 20 % drug containing solid matrices by spray drying method. The formulations were analyzed in terms of dissolution profile, x-ray diffraction (XRD) and/or differential scanning calorimetry (DSC) pattern once immediately after preparation and again after storage for three months at accelerated conditions. The ...
2 CitationsSource
#1Esmaeil Moazeni (Tehran University of Medical Sciences)H-Index: 6
#2Kambiz Gilani (Tehran University of Medical Sciences)H-Index: 26
Last. Mohammad Ali Barghi (UT: University of Tehran)H-Index: 3
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Background This study evaluated the potential of chitosan based polymeric micelles as a nanocarrier system for pulmonary delivery of itraconazole (ITRA).
24 CitationsSource