Manabu Suzuki
Nippon Medical School
Internal medicineRadiologySurgeryPathologyDermatologyCardiologyLung cancerLocal anesthesiaRespiratory failureExacerbationRheumatoid arthritisLungPneumoniaBronchoscopyThoracoscopyBronchiectasisPleural effusionTuberculosisLymphedemaSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)AnesthesiaMedicine
46Publications
5H-index
93Citations
Publications 45
Newest
#1Akinari TsukadaH-Index: 1
#2Manabu SuzukiH-Index: 5
Last. Haruhito SugiyamaH-Index: 19
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We herein report a 67-year-old kidney transplant patient who died of COVID-19. He was treated with hydroxychloroquine and azithromycin and received mechanical ventilation that temporarily improved his respiratory status. Despite our efforts, however, he later developed respiratory failure and died 43 days after the disease onset. The autopsy revealed prominent organization of alveoli and alveolar ducts, with a massive accumulation of macrophages in the lungs. A few SARS-CoV-2 antigen-positive ce...
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#1Takashi KatsunoH-Index: 2
#2Manabu SuzukiH-Index: 5
Last. Haruhito SugiyamaH-Index: 19
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#1Yoshie TsujimotoH-Index: 2
#2Junko TeradaH-Index: 1
Last. Haruhito SugiyamaH-Index: 19
view all 24 authors...
BACKGROUND: The current gold standard in coronavirus disease (COVID-19) diagnostics is the real-time reverse transcription-polymerase chain reaction (RT-PCR) assay for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in nasopharyngeal swab (NPS) samples. Alternatively, nasal swab (NS) or saliva swab (SS) specimens are used, although available data on test accuracy are limited. We examined the diagnostic accuracy of NPS/NS/SS samples for this purpose. METHODS: Ten patien...
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#2Manabu SuzukiH-Index: 5
Last. Haruhito SugiyamaH-Index: 19
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A 62-year-old woman with rheumatoid arthritis and a history of receiving immunosuppressant therapy had a recurrence of lung adenocarcinoma with EGFR L858R mutation. Following 14 months of treatment with erlotinib, computed tomography (CT) findings revealed the presence of small diffuse nodules. Bronchoscopy was performed as metastasis was suspected; however, this was not detected on lung biopsy with forceps. Transbronchial lung cryobiopsy (TBLC) succeeded in detecting metastatic adenocarcinoma, ...
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#1Hiroshi TakumidaH-Index: 2
#2Shinyu IzumiH-Index: 19
Last. Masayuki HojoH-Index: 11
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Abstract A 70-year-old Japanese man contracted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and required oxygen to maintain oxygen saturation (>90%), 5 weeks after onset of coronavirus disease 2019 (COVID-19) symptoms. Transbronchial lung cryobiopsy revealed pathological features of organizing pneumonia with alveolar epithelial injury, and prednisolone administration led to alleviation of respiratory symptoms and recovery of respiratory function. This case report is the...
1 CitationsSource
#1Masaya SugiyamaH-Index: 34
#2Noriko KinoshitaH-Index: 6
Last. Masashi MizokamiH-Index: 97
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COVID-19, a novel coronavirus-related illness, has spread worldwide. Patients with apparently mild/moderate symptoms can suddenly develop severe pneumonia. Therefore, almost all COVID-19 patients require hospitalization, which can reduce limited medical resources in addition to overwhelming medical facilities. To identify predictive markers for the development of severe pneumonia, a comprehensive analysis of serum chemokines and cytokines was conducted using serial serum samples from COVID-19 pa...
8 CitationsSource
#1Satoru IshiiH-Index: 6
#2Hiromu WatanabeH-Index: 1
Last. Masayuki HojoH-Index: 11
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OBJECTIVE New flex-rigid pleuroscope enables observations with a maximum angle of curvature of 180° , allowing visualization of the area near the insertion site of the pleuroscope. And, it improved the image quality and channel inner diameter. The aim of this study was to evaluate the clinical effectiveness and safety of a new flex-rigid pleuroscope. METHODS A retrospective analysis of patients who were examined with a new flex-rigid pleuroscope under local anesthesia at our institution was cond...
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#2Motoyasu IikuraH-Index: 21
Last. Masao HashimotoH-Index: 8
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Bronchial thermoplasty (BT) is an interventional endoscopic treatment for severe bronchial asthma. Some studies have shown the clinical efficacy of this intervention, but its cost-effectiveness is unclear. The aim of this study was to evaluate the cost-effectiveness of BT. We collected data from the medical records of 16 Japanese patients who were treated with BT between February 2015 and April 2017, and compared asthma-related medical expenses between the year preceding and the year following B...
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#2Manabu SuzukiH-Index: 5
Last. Haruhito SugiyamaH-Index: 19
view all 8 authors...
BACKGROUND: Currently, there are no specific effective treatments for SARS-CoV-2; however, various COVID-19 treatment options are under investigation. It is vital to continue investigating the landscape of SARS-CoV-2-induced pneumonia and therapeutic interventions. OBJECTIVE: This paper presents the protocol for a study that aims to compare the pneumonia exacerbation rate between ciclesonide (Alvesco R) administration and symptomatic treatment in COVID-19 patients and to determine the efficacy o...
1 CitationsSource
OBJECTIVE: To evaluate the efficacy and safety of direct hemoperfusion using a polymyxin B-immobilized polystyrene column (PMX-DHP) in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive pneumonia patients. METHODS: This study was a case series conducted at a designated infectious diseases hospital. Twelve SARS-CoV-2-positive patients with partial pressure of arterial oxygen/percentage of inspired oxygen (P/F) ratio < 300 were treated with PMX-DHP on two consecutive days each d...
1 CitationsSource