Anjia Chen
Shanxi Medical University
AnalyteAnalytical chemistryDetection limitIonic liquidChemistryCapillary actionCalibration curveCinchonineCinchonidineCyclodextrinMethanolUncaria rhynchophyllaAmmonium acetateCapillary electrophoresisCinchona AlkaloidsSodium CholateChromatographyMicellar electrokinetic chromatographySodiumResolution (mass spectrometry)
18Publications
7H-index
108Citations
Publications 18
Newest
#1Meijuan Hou (Shanxi Medical University)
#2Yiqiong Zhang (Shanxi Medical University)
Last. Anjia Chen (Shanxi Medical University)H-Index: 7
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In this study, a hydrophobic interaction electrokinetic chromatography method has been developed for simultaneous separation and determination of three diterpenoids in Euphorbiae Lathyris L.: Euphorbia factor L1 , Euphorbia factor L2 and Euphorbia factor L3 . After optimization of separation conditions, the electrolyte solution was 5.0 mM ammonium acetate buffer containing 30 mM sodium dodecyl sulfate in a 60% (v/v) methanol (pH 6.86), 25 kV of electric field across the capillary was applied at ...
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#1Hua Wang (Shanxi Medical University)
#2Yuhang Yang (Shanxi Medical University)
Last. Anjia Chen (Shanxi Medical University)H-Index: 7
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INTRODUCTION Picfeltarraenins IA, IB and IV and acteoside are the four bioactive ingredients of Picria fel-terrae Lour. Their pharmacological effects include central inhibitory, cardiovascular, anti-inflammatory, anti-pyretic, analgesic, anti-bacterial, antioxidative and anti-tumor effects. OBJECTIVE We aimed to develop an efficient micellar electrokinetic chromatography (MEKC) method modified with mixed organic solvents for the simultaneous separation and determination of the four components in...
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#1Yuhang Yang (Shanxi Medical University)
#2Hua Wang (Shanxi Medical University)
Last. Anjia Chen (Shanxi Medical University)H-Index: 7
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Abstract In this study, a simple and sensitive cyclodextrin-modified mixed micellar electrokinetic capillary chromatography (CD-MEKC) method has been developed for the simultaneous separation and determination of Huperzine A (HupA), Huperzine B (HupB) and Huperzine C (HupC) in Huperzia serrata (H. serrata). The optimal conditions (pH 9.3) were composed of 10 mM sodium tetraborate solution, 40 mM sodium dodecyl sulfate (SDS), 50 mM sodium cholate (SC) and 3.0 mM mono-(6-ethylenediamine-6-deoxy)-β...
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#1Mengli Wang (Shanxi Medical University)H-Index: 1
#2Jing Guo (Shanxi Medical University)H-Index: 1
Last. Anjia Chen (Shanxi Medical University)H-Index: 7
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INTRODUCTION: Hirsutine and hirsuteine are the main pharmacological activity ingredients of Uncaria rhynchophylla (UR), playing an important role in treating mental and cardiovascular diseases, such as Alzheimer's disease, hypertension, Parkinson's disease, potential anti-cancer activities and so on. OBJECTIVE: To develop a cyclodextrin-modified micellar electrokinetic capillary chromatography (CD-MEKC) method for the simultaneous separation and determination of hirsutine and hirsuteine from UR ...
5 CitationsSource
#1Jing Guo (Shanxi Medical University)H-Index: 1
#2Mengli Wang (Shanxi Medical University)H-Index: 1
Last. Anjia Chen (Shanxi Medical University)H-Index: 7
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: A simple, comprehensive and efficient capillary electrophoresis method using a dual cyclodextrin system was developed for the simultaneous determination of seven isoflavones (3'-methoxypuerarin, puerarin, 3'-hydroxypuerarin, ononin, daidzin, daidzein and genistin). Baseline separations of the seven isoflavones were achieved within 11 min with the running buffer consisting of 35 mm sodium tetraborate, 9.0 mm sulfobutylether-β-cyclodextrin and 30 mm α-cyclodextrin at pH 9.34, and peaks were dete...
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#1Haitao Guo (Shanxi Medical University)H-Index: 2
#2Zhiying Wang (Shanxi Medical University)H-Index: 3
Last. Anjia Chen (Shanxi Medical University)H-Index: 7
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: A simple, comprehensive, and highly selective MEKC method has been developed for simultaneous analysis of seven bioactive components (triptolide, wilfortrine, wilfordine, wilforgine, wilforine, triptophenolide, and triptonide) in the root extracts of Tripterygium wilfordii Hook. F. (TWHF) and Tripterygium preparations (TPs). Optimal BGE consisted of 10 mM sodium tetraborate, 30 mM SDS, and 30% v/v methanol. The separation voltage was 20 kV and the temperature was 25°C. A DAD was used and the d...
3 CitationsSource
#1Meng Chen (Shanxi Medical University)H-Index: 4
#2Ruimiao Chang (Shanxi Medical University)H-Index: 4
Last. Anjia Chen (Shanxi Medical University)H-Index: 7
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INTRODUCTION: Praeruptorin A, B and C are major bioactive constituents in Peucedani Radix. They display anti-inflammatory effect, anti-hypertension effect, antiplatelet aggregation, potential anti-cancer activities and so on. They are worthy of investigation as potentially novel and versatile drugs. OBJECTIVE: To develop a method using micellar electrokinetic chromatography (MEKC) for the application in simultaneously separation and determination of praeruptorin A, B and C from Peucedani Radix a...
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#1Zhiying Wang (Shanxi Medical University)H-Index: 3
#2Haitao Guo (Shanxi Medical University)H-Index: 2
Last. Anjia Chen (Shanxi Medical University)H-Index: 7
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: A sensitive, fast, and effective method, field-amplified sample stacking (FASS) in capillary electrophoresis, has been established for the separation and determination of corynoxine and corynoxine B. Hydroxypropyl-β-CD (HP-β-CD) and tetrabutylammonium-L-glutamic acid (TBA-L-Glu) were used as additives in the separation system. Electrokinetic injection was chosen to introduce sample from inlet at 10 kV for 50 s after a water plug (0.5 psi, 4 s) was injected to permit FASS. The running buffer (p...
12 CitationsSource
#1Liying Xu (Shanxi Medical University)H-Index: 3
#2Wenyan Zhao (Shanxi Medical University)H-Index: 3
Last. Anjia Chen (Shanxi Medical University)H-Index: 7
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The purpose of this study was to develop a novel, simple and precise ligand-exchange capillary electrophoresis method to separate the diastereomer pairs of four major cinchona alkaloids (quinine/quinidine and cinchonine/cinchonidine). The l-lysine and copper(II) were chosen as the ligand and the central ion, respectively. Optimal separation conditions of four alkaloids were 4.0 mM l-lys, 2.0 mM copper(II) and 30 mM NH4Ac at pH 8.9 and a applied voltage of 15 kV . Meanwhile, the first-order deriv...
1 CitationsSource
#1Meng Chen (Shanxi Medical University)H-Index: 4
#2Yayun Huang (Shanxi Medical University)H-Index: 4
Last. Anjia Chen (Shanxi Medical University)H-Index: 7
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Large-volume Sample Stacking (LVSS) is commonly used as an effective on-line preconcentration method in capillary zone electrophoresis (CZE). In this paper, the method LVSS combined with CZE has been proposed to analysis the camptothecin alkaloids. Optimum separation can be achieved in conditions as following: pH 9.0, 25 mM borate buffer containing 20 mM Sulfobutylether-β-Cyclod- extrin (SBE-β-CD) and 20 mM ionic liquid [EMIM] [L-Lac] (IL), the applied voltage was 20 kV and the capillary tempera...
4 CitationsSource