Adam J. Culbreth
University of Maryland, Baltimore
PsychiatryNeural correlates of consciousnessDevelopmental psychologyPsychologyNeuroscienceCognitionCognitive psychologyWorking memorySchizophrenia (object-oriented programming)AvolitionAnhedoniaPsycINFOPsychosisSchizoaffective disorderTask (project management)Diagnosis of schizophreniaAudiologyNeuroimagingClinical psychologySchizophreniaReinforcement learning
28Publications
13H-index
660Citations
Publications 29
Newest
#1Adam J. Culbreth (UMB: University of Maryland, Baltimore)H-Index: 13
#2M Deanna (WashU: Washington University in St. Louis)H-Index: 106
Last. Erin K. Moran (WashU: Washington University in St. Louis)H-Index: 9
view all 3 authors...
Loneliness is associated with a myriad of detrimental outcomes in mental and physical health. Previous studies have found that people with schizophrenia report greater loneliness than controls, and that loneliness is related to depressive symptoms. However, research has been limited, particularly regarding contributions of loneliness to social and occupational functioning. Further, few studies have examined associations between loneliness and daily experience in schizophrenia. Thus, we recruited...
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#1Adam J. Culbreth (UMB: University of Maryland, Baltimore)H-Index: 13
#2James A. Waltz (UMB: University of Maryland, Baltimore)H-Index: 30
Last. James M. Gold (UMB: University of Maryland, Baltimore)H-Index: 102
view all 4 authors...
Abstract Background The current study aimed to further etiological understanding of the psychological mechanisms underlying negative symptoms in people with schizophrenia. Specifically, we tested whether negative symptom severity is associated with reduced retention of reward-related information over time, and thus a degraded ability to utilize such information to guide future action selection. Methods 44 patients with a diagnosis of schizophrenia or schizoaffective disorder and 28 healthy volun...
3 CitationsSource
#1Adam J. Culbreth (UMB: University of Maryland, Baltimore)H-Index: 13
#2Qiong Wu (UMD: University of Maryland, College Park)H-Index: 1
Last. James A. Waltz (UMB: University of Maryland, Baltimore)H-Index: 30
view all 7 authors...
A growing body of research has suggested that people with schizophrenia (SZ) exhibit altered patterns of functional and anatomical brain connectivity. For example, many previous resting state functional connectivity (rsFC) studies have shown that, compared to healthy controls (HC), people with SZ demonstrate hyperconnectivity between subregions of the thalamus and sensory cortices, as well as hypoconnectivity between subregions of the thalamus and prefrontal cortex. In addition to thalamic findi...
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#1Qiong Wu (UMD: University of Maryland, College Park)H-Index: 1
#2Xiaoqi Huang (Johns Hopkins University)H-Index: 1
Last. Shuo Chen (UMD: University of Maryland, College Park)H-Index: 17
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Abstract Group-level brain connectome analysis has attracted increasing interest in neuropsychiatric research with the goal of identifying connectomic subnetworks (subgraphs) that are systematically associated with brain disorders. However, extracting disease-related subnetworks from the whole brain connectome has been challenging, because no prior knowledge is available regarding the sizes and locations of the subnetworks. In addition, neuroimaging data is often mixed with substantial noise tha...
3 CitationsSource
#1Adam J. CulbrethH-Index: 13
#2Andrew WestbrookH-Index: 12
Last. M DeannaH-Index: 106
view all 4 authors...
Recently, experimental tasks have been developed which index individual differences in willingness to expend effort for reward. However, little is known regarding whether such measures are associated with daily experience of effort. To test this, 31 participants completed an ecological momentary assessment (EMA) protocol, answering surveys regarding the mental and physical demand of their daily activities, and also completed two effort-based decision-making tasks: the Effort Expenditure for Rewa...
1 CitationsSource
Prior research indicates that individuals with schizophrenia (SZ) display emotion regulation abnormalities that are critically linked to increased symptom severity and poor functional outcome. However, processes contributing to the aberrant implementation of various strategies are unclear. The current study took a multimodal approach to identifying mechanisms underlying the impaired implementation of 2 strategies: reappraisal and distraction. Participants included 25 individuals with SZ and 25 h...
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#1Adam J. CulbrethH-Index: 13
#2James A. WaltzH-Index: 30
Last. James M. GoldH-Index: 102
view all 4 authors...
Source
#1Adam J. Culbreth (WashU: Washington University in St. Louis)H-Index: 13
#2Erin K. Moran (WashU: Washington University in St. Louis)H-Index: 9
Last. M Deanna (WashU: Washington University in St. Louis)H-Index: 106
view all 5 authors...
Recent research suggests that schizophrenia is associated with reduced effort allocation. We examined the willingness to expend effort, neural correlates of effort allocation, and the relationship ...
4 CitationsSource
#1Erin K. MoranH-Index: 9
#2Adam J. CulbrethH-Index: 13
Last. M DeannaH-Index: 106
view all 4 authors...
: Negative symptoms are a core clinical feature of schizophrenia that are only marginally responsive to current treatments. Recent work suggests that deficits in reinforcement learning and anticipatory responses to reward may be two mechanisms that help explain impairments in motivation in those with schizophrenia. The present study utilized a reinforcement-learning paradigm, which allowed us to examine both reward anticipation and reinforcement learning. Twenty-eight people with schizophrenia a...
14 CitationsSource
#1Julia A. Ermel (WashU: Washington University in St. Louis)H-Index: 2
#2Erin K. Moran (WashU: Washington University in St. Louis)H-Index: 9
Last. M Deanna (WashU: Washington University in St. Louis)H-Index: 106
view all 4 authors...
Abstract Research examining psychotic disorders typically involves comparison between individuals with a clinical disorder and healthy controls. However, research suggests that psychotic symptoms, such as delusions and hallucinations, may exist on a continuum ranging from variation in healthy individuals to diagnosable psychotic disorders. On this continuum, some individuals endorse occasional psychotic like experiences (PLEs) that do not cause sufficient impairment or distress to warrant a clin...
5 CitationsSource