Ting Liu
Shenyang Pharmaceutical University
BioassayPharmacokineticsAnalytical chemistryIonMass spectrometryFourier transform ion cyclotron resonanceNutraceuticalHigh-performance liquid chromatographyChemistryDecoctionDemethylationRadixMetabolomicsSuperoxide dismutaseMaximPinelliaPhaseolusLiver injuryAcetic acidIsoliquiritigeninOral administrationAcetonitrileAconitineAlcoholic liver diseasePalmitoylcarnitineFatty acid amideMyricetinRadiatusMalondialdehydeLiquiritigeninGlucuronideOleamideVitexinIsovitexinUrineBaicalinLiquiritinHydroxylationQuercetinGegenqinlianActive componentsUhplc msSingle oral doseElectrospray ionizationChromatographyFatty acidBiochemistryTraditional medicineMetabolismSelected reaction monitoringProtein precipitationBeta oxidationBiologyCatabolismPharmacology
10Publications
6H-index
60Citations
Publications 9
Newest
#1Xueyan Yang (SPU: Shenyang Pharmaceutical University)H-Index: 2
#2Liye Yan (SPU: Shenyang Pharmaceutical University)H-Index: 1
Last. Zhiguo Yu (SPU: Shenyang Pharmaceutical University)H-Index: 16
view all 7 authors...
Abstract A selective, sensitive and fully validated liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was established for the determination of dihydromyricetin, dihydroquercetin, myricetin and quercetin in rat plasma after intragastric administration of Hoveniae Semen total flavonoids. Baicalin was selected as the internal standard. Analytes were extracted from the rat plasma by protein precipitation with acetonitrile and separated on a C18 chromatographic column (Agilent ZORBAX E...
5 CitationsSource
#1Yue Cui (SPU: Shenyang Pharmaceutical University)H-Index: 7
#2Ting Liu (SPU: Shenyang Pharmaceutical University)H-Index: 6
Last. Zhiguo Yu (SPU: Shenyang Pharmaceutical University)H-Index: 16
view all 9 authors...
Abstract Incompatible herb pair Gansui-Gancao is recorded in “eighteen incompatible” medicaments in many monographs of TCM (Traditional Chinese Medicine) which means the two herbs can not be co-used in most cases. However, Gansuibanxia decoction composed of Gansui(Kansui), Banxia(Pinellia), Shaoyao(Peony) and Gancao(Liquorice) is a traditional Chinese formula which has been clinically employed for the treatment of cancerous ascites, pleural effusion, peritoneal effusion, etc. The purpose of the ...
9 CitationsSource
#1Xiumin TianH-Index: 3
#2Xiuying YanH-Index: 2
view all 7 authors...
#1Ting Liu (SPU: Shenyang Pharmaceutical University)H-Index: 6
#2Xiumin Tian (SPU: Shenyang Pharmaceutical University)H-Index: 3
Last. Zhiguo Yu (SPU: Shenyang Pharmaceutical University)H-Index: 16
view all 7 authors...
Abstract Gegenqinlian decoction (GQLD) as a traditional Chinese medical (TCM) prescription is made from four Chinese herbs and has been used for centuries to treat pyrexia and diarrhea. In this work, an ultra-high performance liquid chromatography coupled with Fourier transform ion cyclotron resonance mass spectrometry (UHPLC-FT-ICR-MS) method was established to profile the metabolic fate of GQLD in rat plasma, urine, bile and feces. The analysis was performed on a Waters Acquity UPLC HSS T3 col...
17 CitationsSource
#1Ting Liu (SPU: Shenyang Pharmaceutical University)H-Index: 6
#2Yue Cui (SPU: Shenyang Pharmaceutical University)H-Index: 2
Last. Zhiguo Yu (SPU: Shenyang Pharmaceutical University)H-Index: 16
view all 8 authors...
Gegenqinlian decoction (GQLD) is one of the classic traditional Chinese medicines. The formula consists of four herbal medicines including Radix Puerariae lobatae, Radix Scutellariae, Coptidis Rhizoma, and Glycyrrhizae Radix et Rhizoma Praeparata Cum Melle. In this study, an ultra-high performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry method was employed to investigate the major constituents in GQLD. Liquid chromatographic separation was ...
8 CitationsSource
#1Ting Liu (SPU: Shenyang Pharmaceutical University)H-Index: 6
#2Songhe Li (SPU: Shenyang Pharmaceutical University)H-Index: 2
Last. Zhiguo Yu (SPU: Shenyang Pharmaceutical University)H-Index: 16
view all 8 authors...
Abstract Pyrexia usually is a systemic pathological process that can lead to metabolic disorders. Metabonomics as a powerful tool not only can reveal the pathological mechanisms, but also can give insight into the progression of pyrexia from another angle. Thus, an ultra high performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry (UHPLC-FT-ICR-MS) metabonomic approach was employed for the first time to investigate the plasma biochemical charac...
7 CitationsSource
#1Ting LiuH-Index: 6
#2Songhe LiH-Index: 2
Last. Zhiguo Yu
view all 8 authors...
Pyrexia usually is a systemic pathological process that can lead to metabolic disorders. Metabonomics as a powerful tool not only can reveal the pathological mechanisms, but also can give insight into the progression of pyrexia from another angle. Thus, an ultra high performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry (UHPLC-FT-ICR-MS) metabonomic approach was employed for the first time to investigate the plasma biochemical characteristics...
#1Ting Liu (SPU: Shenyang Pharmaceutical University)H-Index: 6
#2Xiao Han Yu (SPU: Shenyang Pharmaceutical University)H-Index: 1
Last. Zhi Guo Yu (SPU: Shenyang Pharmaceutical University)H-Index: 1
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The aim of the present study was to investigate the potential hepatoprotective effects of flavonoids from mung beans in an alcohol-induced liver injury mouse model. Mung bean extract (ME) was obtained by extraction with 75% ethanol, followed by concentration and lyophilization. Two major flavonoids (TMF) were isolated from mung beans and authenticated as vitexin and isovitexin. The hepatoprotective effect of ME and TMF against liver damage was investigated by measuring the serum levels of alanin...
11 CitationsSource
#1Enze Gao (SPU: Shenyang Pharmaceutical University)H-Index: 4
#2Xiaohan Yu (SPU: Shenyang Pharmaceutical University)H-Index: 2
Last. Zhiguo Yu (SPU: Shenyang Pharmaceutical University)H-Index: 16
view all 8 authors...
The study was aimed to investigate the effects of single and multiple oral administration of mungbean (Phaseolus radiatus L.) seed extract (ME) on the pharmacokinetics of aconitine in rats. The Sprague–Dawley rats were randomly divided into three groups (six rats each group). In group 1, rats were orally administered 500 µg/kg aconitine after receiving a single oral dose of 1 g/kg ME. In group 2, rats were orally administered with 500 µg/kg aconitine at day 7 of treatment with 1 g/kg/day ME. In ...
7 CitationsSource