Claudio Farina
Istituto Superiore di Sanità
EpidemiologyDrug resistanceOutbreakInternal medicineSurgeryPathologyVirologyIntensive care medicinePediatricsProspective cohort studyImmunologyKlebsiella pneumoniaeAmikacinBacteremiaAntifungalMycosisCandida albicansTypingSerologyAntimicrobialAntibioticsMedicineMultilocus sequence typingBiologyMicrobiology
91Publications
18H-index
1,198Citations
Publications 96
Newest
#1Matteo Perini (University of Milan)H-Index: 4
#2Aurora Piazza (UNIPV: University of Pavia)H-Index: 11
view all 16 authors...
Objectives Subspecies pathogen typing is a pivotal tool to detect the emergence of high-risk clones null in hospital settings and to limit their spreading among patients. Unfortunately, the most used subspecies typing methods (i.e. Pulsed-field Gel Electrophoresis - PFGE, Multi-Locus Sequence Typing - MLST and Whole Genome Sequencing - WGS) are too expensive and time consuming to be suitable for real-time surveillance. Here we present Hypervariable-Locus Melting Typing (HLMT), a novel subspecies...
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#1Giuseppe Russello (AUSL: Academy for Urban School Leadership)H-Index: 8
#2Antonio Moramarco (AUSL: Academy for Urban School Leadership)H-Index: 4
Last. Edoardo Carretto (AUSL: Academy for Urban School Leadership)H-Index: 22
view all 6 authors...
ABSTRACT null null Rapid identification of causative microorganisms of microbial keratitis (MK) and knowledge of the most common local pathogens are prerequisites for rational antimicrobial therapy. We retrospectively reviewed the characteristics of MK diagnosed at the IRCCS Arcispedale Santa Maria Nuova of Reggio Emilia (Italy) in a 5-years period, where the Ophthalmologist Unit is a reference center for corneal infections. null During the study period, 183 MK were analyzed through corneal scra...
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#1Annapaola CallegaroH-Index: 17
#2Daniela BorleriH-Index: 1
Last. Franco MaggioloH-Index: 31
view all 7 authors...
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic calls for rapid actions, now principally oriented to a world-wide vaccination campaign. In this study we verified if, in individuals with a previous SARS-CoV-2 infection, a single dose of messenger RNA (mRNA) vaccine would be immunologically equivalent to a full vaccine schedule in naive individuals. Health care workers (184) with a previous SARS-CoV-2 infection were sampled soon before the second dose of vaccine and betwe...
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#1Federico Raimondi (University of Milan)H-Index: 6
#2Luca NovelliH-Index: 3
Last. Fabiano Di Marco (University of Milan)H-Index: 26
view all 43 authors...
Background Gender-related factors might affect vulnerability to Covid-19. The aim of this study was to describe the role of gender on clinical features and 28-day mortality in Covid-19 patients. Methods Observational study of Covid-19 patients hospitalized in Bergamo, Italy, during the first three weeks of the outbreak. Medical records, clinical, radiological and laboratory findings upon admission and treatment have been collected. Primary outcome was 28-day mortality since hospitalization. Resu...
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#1Luca NovelliH-Index: 3
#2Federico RaimondiH-Index: 6
Last. Stefano FagiuoliH-Index: 55
view all 44 authors...
BACKGROUND: Findings from February, 2020, indicate that the clinical spectrum of Covid-19 can be heterogeneous, probably due to the infectious dose and viral load of SARS-CoV-2 within the first weeks of the outbreak. The aim of this study was to investigate predictors of overall 28-day mortality at the peak of the Italian outbreak. METHODS: Retrospective observational study of all Covid-19 patients admitted to the main hospital of Bergamo, from February 23 to March, 14, 2020. RESULTS: 508 patien...
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This paper aims to describe the etiology of bloodstream infections in COVID-19, Papa Giovanni XXIII Hospital, Bergamo, Italy. Two periods were evaluated: February 22-May 21, 2019/2020. We considered: the number of patients and blood culture sets, species of isolates (bacteria, specifically those indicated by EARS criteria; CoNS; Candida albicans) and their antibiotic sensitivity. In 2020 Escherichia coli and Carbapenemase-producing Klebsiella pneumoniae disappeared. Candida albicans and MDR Pseu...
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#1Anna Prigitano (University of Milan)H-Index: 18
#2C. CavannaH-Index: 15
Last. Anna Maria Tortorano (University of Milan)H-Index: 37
view all 19 authors...
Abstract Background: Fungemia represents a public health concern. Knowing aetiology and activity of the antifungals is critical for the management of bloodstream infections. Therefore, surveillance on local/international levels is desirable for a prompt administration of appropriate therapy. Methods: Data on fungi responsible for fungemia and antifungal susceptibility profiles were collected from a laboratory-based surveillance over 2016-17 in 12 hospitals located in Lombardia, Italy. The trend ...
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#1Matteo Perini (University of Milan)H-Index: 4
#2Aurora Piazza (University of Milan)H-Index: 11
Last. Francesco Comandatore (University of Milan)H-Index: 15
view all 12 authors...
In this work we present EasyPrimer, a user-friendly online tool developed to assist pan-PCR and High Resolution Melting (HRM) primer design. The tool finds the most suitable regions for primer design in a gene alignment and returns a clear graphical representation of their positions on the consensus sequence. EasyPrimer is particularly useful in difficult contexts, e.g. on gene alignments of hundreds of sequences and/or on highly variable genes. HRM analysis is an emerging method for fast and co...
Source
#1Matteo Perini (University of Milan)H-Index: 4
#2Aurora Piazza (University of Milan)H-Index: 11
Last. Francesco Comandatore (University of Milan)H-Index: 15
view all 12 authors...
In this work we present EasyPrimer, a user-friendly online tool developed to assist pan-PCR and High Resolution Melting (HRM) primer design. The tool finds the most suitable regions for primer design in a gene alignment and returns a clear graphical representation of their positions on the gene. EasyPrimer is particularly useful in difficult contexts, e.g. on gene alignments of hundreds of sequences and/or on highly variable genes. HRM analysis is an emerging method for fast and cost saving bact...
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