Xiaoyan Zhu
Northwest A&F University
Messenger RNAFGF21Subclinical infectionInternal medicineEndocrinologyAnimal scienceGene expressionMolecular biologyAlkaline phosphataseFetusChemistryExtracellular matrixIn vitroWestern blotLactationInsulinNEFAWeight gainCartilageInsulin-like growth factorMethionineChondrocyteStrontiumCopperBiochemistryCell growthHormoneMedicineBiologyCell biology
16Publications
8H-index
126Citations
Publications 16
Newest
#1Yan Huang (NWAFU: Northwest A&F University)H-Index: 2
#2Jing Wen (NWAFU: Northwest A&F University)H-Index: 2
Last. Baoyu Zhao (NWAFU: Northwest A&F University)H-Index: 7
view all 12 authors...
Background null A better comprehension of the redox status during the periparturient period may facilitate the development of management and nutritional solutions to prevent subclinical hyperketonemia (SCHK) and subclinical hypocalcemia (SCHC) in dairy goats. We aimed to evaluate the variation in the redox status of dairy goats with SCHK and SCHC during their periparturient periods. Guanzhong dairy goats (n = 30) were assigned to SCHK (n = 10), SCHC (n = 10), and healthy (HEAL, n = 10) groups ba...
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#8Binyun Cao (NWAFU: Northwest A&F University)H-Index: 14
#9Jianguo Wang (NWAFU: Northwest A&F University)H-Index: 12
Background: Dairy goats are highly susceptible to subclinical hyperketonemia (SCHK) during the transition period. This study aimed to compare the variation in metabolic parameters and surrogate indexes of insulin resistance (sIR) between goats with SCHK and clinically healthy (HEAL) goats during the transition period. Methods: Twenty Guanzhong dairy goats were assorted to HEAL (n = 10) and SCHK (n = 10) groups according to the blood β-hydroxybutyrate (BHBA) concentrations. The blood samples were...
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#1Jianguo Wang (NWAFU: Northwest A&F University)H-Index: 12
#2Xiaoyan Zhu (NWAFU: Northwest A&F University)H-Index: 8
Last. Baoyu Zhao (NWAFU: Northwest A&F University)H-Index: 7
view all 3 authors...
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#1Jinfeng Zhang (Qinghai University)H-Index: 1
#2Xiaoyan Zhu (NWAFU: Northwest A&F University)H-Index: 8
Last. Jianguo Wang (NWAFU: Northwest A&F University)H-Index: 12
view all 9 authors...
Abstract The trace element strontium has a significant impact on cartilage metabolism. However, the direct effects of strontium on alkaline phosphatase (ALP), a marker of bone growth, and bone morphogenetic protein-4 (BMP-4), which plays a key role in the regulation of bone and cartilage development, are not entirely clear. In order to understand the mechanisms involved in these processes, the chondrocytes were isolated from Wistar rat articular cartilage by enzymatic digestion and cultured unde...
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#1Xiaoyan Zhu (NWAFU: Northwest A&F University)H-Index: 8
#2Yezi Kong (NWAFU: Northwest A&F University)H-Index: 5
Last. Jianguo Wang (NWAFU: Northwest A&F University)H-Index: 12
view all 5 authors...
Strontium (Sr) can reduce cartilage degeneration and stimulate cartilage matrix formation. Angiogenesis plays a developmental role in chondrogenesis, and was stimulated by growth factors such as vascular endothelial growth factor (VEGF) and fibroblast growth factor 2 (FGF2). However, the direct influence of Sr on VEGF and FGF2 expressions in chondrocytes is not entirely clear. The objective of this study was to investigate the effects of different Sr concentrations on VEGF and FGF2 expressions i...
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#1Jianguo Wang (NWAFU: Northwest A&F University)H-Index: 12
#2Xiaoyan Zhu (NWAFU: Northwest A&F University)H-Index: 8
Last. Baoyu Zhao (NWAFU: Northwest A&F University)H-Index: 7
view all 8 authors...
During peripartum period, dairy cows are highly susceptible to energy metabolism disorders such as fatty liver and ketosis. Angiopoietin-like protein 4 (ANGPTL4) and fibroblast growth factor 21 (FGF21), known as hepatokines, play important roles in lipid metabolism. The purposes of our study were to evaluate variations of serum ANGPTL4 and FGF21 concentrations in periparturient dairy cows and changes in these serum analyte concentrations of energy-related metabolic disorders in early lactation d...
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#1Xiaoyan ZhuH-Index: 8
#2Jianguo WangH-Index: 12
Last. Lei LiuH-Index: 14
view all 3 authors...
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#1Jianguo Wang (NWAFU: Northwest A&F University)H-Index: 12
#2Xiaoyan Zhu (French Institute of Health and Medical Research)H-Index: 8
Last. Guowen Liu (JLU: Jilin University)H-Index: 27
view all 7 authors...
To investigate the effect of dietary copper on serum growth-related hormones levels and growth performance, a total of 60 weanling pigs were randomly assigned to six groups each containing 10 pigs, fed on basal diets supplemented with 0 (control), 100, 150, 200, 250, and 300 mg/kg copper sulfate for 80 days, respectively. The average daily gain (ADG), feed to gain ratio (F/G), feed intake and serum growth hormone (GH), insulin (INS), insulin-like growth factor 1 (IGF-1), and insulin-like growth ...
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#1Jianguo Wang (JLU: Jilin University)H-Index: 12
#2Xiaoyan Zhu (JLU: Jilin University)H-Index: 8
Last. Guowen Liu (JLU: Jilin University)H-Index: 27
view all 9 authors...
Strontium stimulates cartilage matrix formation in vitro. However, the mechanisms governing these effects have not yet been extensively reported. In this study, chondrocytes were isolated from rat articular cartilage by enzymatic digestion and cultured for 24–72 h with 1–5 mM strontium. We investigated the effects of different concentrations of strontium on collagen content, type II collagen, insulin-like growth factor (IGF-1) and matrix metalloproteinase (MMP)-13 expression in rat cultured arti...
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#1Wenyan Yang (JLU: Jilin University)H-Index: 2
#2Jianguo Wang (JLU: Jilin University)H-Index: 12
Last. Guowen Liu (JLU: Jilin University)H-Index: 27
view all 10 authors...
This experiment was conducted to examine the effect of dietary copper supplementation on ghrelin mRNA expression level in the fundic gland of growing pigs. A total of 45 crossbred pigs were randomly assigned to three groups of 15 pigs, five replicates of three animals comprised each group. Pigs were allocated to diets that contained 5 mg/kg copper (as the control group), 125 mg/kg copper sulfate, or 125 mg/kg copper methionine. At the end of the experiment, five pigs were selected at random from...
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