Takahito Niikura
Jikei University School of Medicine
ExcretionSubclinical infectionInternal medicineUrologyCalcineurinPathologyTransferrin saturationAntibodyABO blood group systemPediatricsHuman leukocyte antigenImmunologyBiopsySudden cardiac deathPlasma cellAzathioprineHepcidinNephritisNeutropeniaStatus epilepticusMetabolic disorderHemodialysisEpilepsyAnemiaFerritinMedullary ray (anatomy)Kidney diseaseMicroscopic polyangiitisHemoglobinPeritoneal dialysisTonsillectomyITPAProteinuriaUric acidDialysisVenous thrombosisKidneyKidney transplantationCreatinineMethylprednisoloneFibrosisRituximabPeritubular capillariesRenal biopsyNephrocalcinosisMesangial hypercellularityTransplantationConvulsive seizureUnexpected deathChange over timeCoronary risk factorsNephrologyThiopurine methyltransferaseMedicineUrinary systemGastroenterology
10Publications
4H-index
23Citations
Publications 10
Newest
#1Yukio Maruyama (Jikei University School of Medicine)H-Index: 18
#2Takahito Niikura (Jikei University School of Medicine)H-Index: 4
Last. Takashi Yokoo (Jikei University School of Medicine)H-Index: 28
view all 5 authors...
Anemia treatment is crucial in the management of dialyzed patients. Although Hb and serum ferritin levels are commonly used as indicators for treatment, these values change over time due to changes in policy, drugs for treating anemia, and target levels suggested by clinical guidelines. To clarify long-term changes in anemia-related parameters in Japan, we extracted annual patient data from a newly developed web-based system by the Japanese Society for Dialysis Therapy, the Web-based Analysis of...
Source
#2Go Kanzaki (Jikei University School of Medicine)H-Index: 12
Last. Takashi Yokoo (Jikei University School of Medicine)H-Index: 28
view all 9 authors...
Sudden unexpected death in epilepsy (SUDEP) has been defined as a sudden/unexpected, witnessed/unwitnessed, nontraumatic, and nondrowning death in epileptic patients with/without seizure evidence and documented status epilepticus. Identified as the leading cause of epilepsy-related deaths, SUDEP cases are highly unrecognized and underreported due to diagnostic difficulty. We report a case of a successfully revived hemodialysis patient who developed cardiopulmonary arrest after a witnessed convul...
Source
#1Takahito Niikura (Jikei University School of Medicine)H-Index: 4
#2Yukio Maruyama (Jikei University School of Medicine)H-Index: 18
Last. Takashi Yokoo (Jikei University School of Medicine)H-Index: 28
view all 9 authors...
: The serum levels of hepcidin generally increase in patients with chronic kidney disease (CKD) due to inflammation or a decline in the glomerular filtration rate. However, the differences in the ferrokinetics among dialysis modalities are unclear. We investigated the relationship between serum levels of hepcidin and ferritin among non-dialyzed CKD (ND), hemodialysis (HD), and peritoneal dialysis (PD) patients. We recruited 285 CKD patients (117 ND, 80 HD, and 88 PD patients) and measured the se...
1 CitationsSource
#1Kosuke HondaH-Index: 1
#2Akimitsu KobayashiH-Index: 8
Last. Takashi YokooH-Index: 28
view all 13 authors...
: A 68-year-old Japanese man was monitored for chronic kidney disease (CKD), with unknown primary disease starting in 2014. His serum creatinine (sCr) was stable at ~ 2.5 mg/dL for ~ 2 years. Two weeks before admission, he had bloody sputum, and sCr increased to 4.63 mg/dL. Soon after admission, the patient developed a high fever with pigment spots on the legs. A kidney biopsy was performed. The kidney specimens showed necrotizing and crescentic glomerulonephritis without granuloma formation. An...
2 CitationsSource
#1Takahito Niikura (Jikei University School of Medicine)H-Index: 4
#2A. Kobayashi (Jikei University School of Medicine)
Last. Kazunari TanabeH-Index: 54
view all 16 authors...
Abstract Background Previously, we explored the histopathologic characteristics of medullary ray injury (MRI) inducing interstitial fibrosis and tubular atrophy (IF/TA) to determine its etiologies, which include calcineurin inhibitor (CNI) toxicity and urologic complications. However, we did not examine the effects of these etiologies on long-term kidney allograft prognosis, because biopsy timing differed among cases. Aim We examined the influence of early MRI on kidney allograft prognosis using...
Source
#1Takahito NiikuraH-Index: 4
Last. Yudo TannoH-Index: 8
view all 16 authors...
#1Takafumi Yamakawa (Jikei University School of Medicine)H-Index: 9
#2Izumi Yamamoto (Jikei University School of Medicine)H-Index: 12
Last. Takashi Yokoo (Jikei University School of Medicine)H-Index: 28
view all 19 authors...
We report a case of recurrent Henoch-Schonlein purpura nephritis (HSPN) treated successfully with a tonsillectomy and steroid pulse therapy in a kidney transplant patient. A 29-year-old woman was admitted to our hospital for an episode biopsy; she had a serum creatinine (S-Cr) of 1.0 mg/dL and 1.34 g/day proteinuria 26 months after kidney transplantation. Histological examination revealed increased amounts of mesangial matrix and mesangial hypercellularity with IgA deposition. Of note, one glome...
5 CitationsSource
#1Yusuke OkabayashiH-Index: 8
#2Izumi YamamotoH-Index: 12
Last. Takashi YokooH-Index: 28
view all 19 authors...
We report a rare case of nephrocalcinosis caused by hereditary renal hypouricaemia 3 months after kidney transplantation. A 41-year-old man who underwent living-related kidney transplantation from his father was admitted to our hospital for a protocol biopsy; he had a serum creatinine (S-Cr) of 1.37 mg/dL and no proteinuria. Histologically, there was no evidence of rejection or calcineurin inhibitor toxicity, although scattered nephrocalcinosis was observed in the distal tubules. Perioperatively...
5 CitationsSource
#1Ai Katsuma (Jikei University School of Medicine)H-Index: 5
#2Izumi Yamamoto (Jikei University School of Medicine)H-Index: 12
Last. Takashi Yokoo (Jikei University School of Medicine)H-Index: 28
view all 17 authors...
A 56-year-old man who had undergone cadaveric kidney transplantation 21 months earlier was admitted to our hospital for a protocol biopsy; he had a serum creatinine level of 1.2 mg/dL and no proteinuria. Histological features showed two distinct entities: (i) inflammatory cell infiltration, in the glomerular and peritubular capillaries and (ii) focal, aggressive tubulointerstitial inflammatory cell infiltration, predominantly plasma cells, with mild tubulitis (Banff 13 classification: i2, t1, g2...
5 CitationsSource
#1Takahito Niikura (Jikei University School of Medicine)H-Index: 4
#2Izumi Yamamoto (Jikei University School of Medicine)H-Index: 12
Last. Takashi Yokoo (Jikei University School of Medicine)H-Index: 28
view all 16 authors...
We report a case of probable C4d-negative accelerated acute antibody-mediated rejection due to non-HLA antibodies. A 44 year-old male was admitted to our hospital for a kidney transplant. The donor, his wife, was an ABO minor mismatch (blood type O to A) and had Gitelman syndrome. Graft function was delayed; his serum creatinine level was 10.1 mg/dL at 3 days after transplantation. Open biopsy was performed immediately; no venous thrombosis was observed during surgery. Histology revealed moderat...
5 CitationsSource