Salvatore Alfieri
University of Milan
CancerInternal medicineRadiologySurgeryPathologyOncologyRetrospective cohort studyAdverse effectHead and neck cancerChemotherapyHead and neck squamous-cell carcinomaImmunotherapySalivary gland cancerMucositisDiseaseAdenoid cystic carcinomaCetuximabPopulationNasopharyngeal cancerLocally advancedIn patientHead and neckCancer researchProportional hazards modelRadiation therapyMedicine
Publications 101
#1Salvatore AlfieriH-Index: 14
Last. Lisa Licitra (University of Milan)H-Index: 67
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To identify and validate baseline magnetic resonance imaging (b-MRI) radiomic features (RFs) as predictors of disease outcomes in effectively cured head and neck squamous cell carcinoma (HNSCC) pat...
#1Giuseppe FanettiH-Index: 9
#2Jerry PoleselH-Index: 61
Last. Giovanni FranchinH-Index: 21
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Background: The Prognostic Nutritional Index (PNI) is a parameter of nutritional and inflammation status related to toxicity in cancer treatment. Since data for head and neck cancer are scanty, this study aims to investigate the association between PNI and acute and late toxicity for this malignancy. Methods: A retrospective cohort of 179 head and neck cancer patients treated with definitive radiotherapy with induction/concurrent chemotherapy was followed-up (median follow-up: 38 months) for tox...
#1Stefano Cavalieri (University of Milan)H-Index: 8
#2Elena Colombo (University of Milan)H-Index: 13
Last. Lisa Licitra (University of Milan)H-Index: 67
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OBJECTIVE: To capture and monitor flu-like symptoms in relation to the clinical characteristics and the oncologic treatment of a large head and neck cancer (HNC) patient cohort during the Coronavirus disease 2019 (COVID-19) pandemic. METHODS: Patients were monitored through by 2 rounds of interviews. Clinical characteristics of patients with no symptoms (group 0) and of those reporting ⩾1 (group A), ⩾3 (group B), or ⩾5 symptoms (group C) were analyzed. Patients with ⩾1 symptom at both in...
#1Francesca Platini (University of Milan)H-Index: 5
#2Stefano Cavalieri (University of Milan)H-Index: 8
Last. Laura D. Locati (University of Milan)H-Index: 31
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PURPOSE Radioactive-iodine (RAI)-resistant differentiated thyroid cancer (DTC) patients benefit from multi-kinase inhibitors (MKIs), such as lenvatinib. Incidence of treatment-related (TR) late toxicities has been not yet described. METHODS From January 2015 to June 2019 we retrospectively reviewed clinical records of patients with RAI-resistant DTC treated with lenvatinib at Istituto Nazionale dei Tumori (Milan, Italy). New side effect of any grade, appeared after 12 months of lenvatinib, was d...
#1Chiara TrevisiolH-Index: 10
#2Massimo GionH-Index: 30
Last. Paolo Bossi (University of Brescia)H-Index: 39
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Abstract Background In EBV-related nasopharyngeal carcinoma (NPC), quantitative determination of circulating EBV-DNA (cEBV-DNA) can potentially be applied as disease marker. The aim of the study was to investigate if the clinical utility of cEBV-DNA is established in clinical practice guidelines and if recommendations are provided to standardize the quantitative cEBV-DNA determination. Methods A systematic literature search for NPC guidelines published since 2011 was performed. Information for c...
PURPOSE To describe the management and outcomes of loco-regionally advanced (stages III-IV) laryngeal cancer (LRALC) in elderly patients. METHODS Clinical records of 88 LRALC patients treated at our Institution from 2002 to 2017 were retrospectively reviewed. Patients were divided in 2 subgroups: age > 65 years (elderly) and age ≤ 65 years (controls). Survivals were estimated with Kaplan-Meier method and compared with log-rank test, multivariate analysis were performed with Cox proportional haza...
#1A. CavalloH-Index: 7
#2Tiziana RancatiH-Index: 27
Last. E. OrlandiH-Index: 3
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#1E. OrlandiH-Index: 3
#2Giuseppina CalaresoH-Index: 14
Last. Marco BolognaH-Index: 6
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#1Marco Bologna (Polytechnic University of Milan)H-Index: 6
#2Valentina D. A. Corino (Polytechnic University of Milan)H-Index: 15
Last. Ester OrlandiH-Index: 22
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Advanced stage nasopharyngeal cancer (NPC) shows highly variable treatment outcomes, suggesting the need for independent prognostic factors. This study aims at developing a magnetic resonance imaging (MRI)-based radiomic signature as a prognostic marker for different clinical endpoints in NPC patients from non-endemic areas. A total 136 patients with advanced NPC and available MRI imaging (T1-weighted and T2-weighted) were selected. For each patient, 2144 radiomic features were extracted from th...
1 CitationsSource
Objective: This study aimed to look into the relationship between intensity-modulated-radiotherapy (IMRT)- or volumetric-modulated-arc-therapy (VMAT)-based dose-volume parameters and 5-year outcome for a consecutive series of non-metastatic nasopharyngeal cancer (NPC) patients (pts) treated in a single institution in a non-endemic area in order to identify potential prognostic factors. Materials and methods: A retrospective analysis of consecutive non-metastatic NPC pts treated curatively with I...
2 CitationsSource