Robert M. Califf
Durham University
Internal medicineSurgeryCardiologyRandomized controlled trialIntensive care medicineStreptokinaseAcute coronary syndromeHeart failureCoronary artery diseaseRevascularizationThrombolysisAngioplastyPercutaneous coronary interventionPopulationAnesthesiaMyocardial infarctionStrokeClinical trialMedicineEjection fraction
Publications 1557
#1Sheryl L. ChowH-Index: 11
#2Comilla SassonH-Index: 30
Last. Eduardo SanchezH-Index: 15
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The misuse of opioids continues to be epidemic, resulting in dependency and a recent upsurge in drug overdoses that have contributed to a significant decrease in life expectancy in the United States. Moreover, recent data suggest that commonly used opioids for the management of pain may produce undesirable pharmacological actions and interfere with critical medications commonly used in cardiovascular disease and stroke; however, the impact on outcomes remains controversial. The American Heart As...
The most common screening tool for depression is the Patient Health Questionnaire-9 (PHQ-9). Despite extensive research on the clinical and behavioral implications of the PHQ-9, data are limited on the relationship between PHQ-9 scores and social determinants of health and disease. To assess the relationship between the PHQ-9 at intake and other measurements intended to assess social determinants of health. Cross-sectional analyses of 2502 participants from the Baseline Health Study (BHS), a pro...
#1Sabina Sayeed (NUS: National University of Singapore)
#2Robert M. CaliffH-Index: 210
Last. Michael Pignone (University of Texas at Austin)H-Index: 93
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Newer data platforms offer increased opportunity to share multidimensional health data with research participants, but the preferences of participants for which data to receive and how is evolving. Our objective is to describe the preferences and expectations of participants for the return of individual research results within Project Baseline Health Study (PBHS). The PBHS is an ongoing, multicenter, longitudinal cohort study with data from four initial enrollment sites. PBHS participants are re...
Abstract null null Introduction null In the 2016 U.S. Presidential election, voters in communities with recent stagnation or decline in life expectancy were more likely to vote for the Republican candidate than in prior Presidential elections. We aimed to assess the association between change in life expectancy and voting patterns in the 2020 Presidential election. null null null Methods null With data on county-level life expectancy from the Institute for Health Metrics and Evaluation and votin...
1 CitationsSource
#1Anthony P. Carnicelli (Duke University)H-Index: 10
#2Anne S. Hellkamp (Duke University)H-Index: 57
Last. Christopher C. Nessel (Johnson & Johnson)H-Index: 7
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Background In event‐driven clinical trials, study termination is based on accrual of a target number of primary efficacy events. For noninferiority trials in which superiority is conditionally exam...
During the past year, clinicians and the public have been focused on the coronavirus disease 2019 (COVID-19) pandemic and its associated societal and economic effects. However, once the acute phase of this crisis has passed, we will face an enormous wave of death and disability as a result of common chronic diseases (CCDs), with cardiometabolic diseases at the crest (Figure). A tsunami results when an earthquake on the ocean floor creates huge waves that can wreak devastation far distant from th...
2 CitationsSource
1 CitationsSource
#1David P. MillerH-Index: 55
Last. William J. MarksH-Index: 32
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BackgroundMuch of the early data on COVID-19 symptomatology was captured in the hospital setting. In a community setting the symptoms most predictive of SARS-CoV-2 positivity may be different. Data from the California sites of a COVID-19 community testing program are presented here. MethodsPrior to being tested, participants in the Baseline COVID-19 Testing Program completed an online screener, in which they self-reported basic demographics and the presence or absence of 10 symptoms. Both positi...