Dimitris Tousoulis
Athens State University
Internal medicineEndocrinologySurgeryCardiologyIntensive care medicineArterial stiffnessInflammationEndotheliumHeart failureCoronary artery diseaseDiseaseEndothelial dysfunctionIn patientMyocardial infarctionDiabetes mellitusBioinformaticsMedicineBlood pressurePharmacology
1,206Publications
81H-index
14.8kCitations
Publications 1198
Newest
#1Edina Cenko (UNIBO: University of Bologna)H-Index: 16
#2Lina BadimonH-Index: 99
Last. Etto C. Eringa (UM: Maastricht University)H-Index: 28
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The cardiovascular system is significantly affected in coronavirus disease-19 (COVID-19). Microvascular injury, endothelial dysfunction and thrombosis resulting from viral infection or indirectly related to the intense systemic inflammatory and immune responses are characteristic features of severe COVID-19. Pre-existing cardiovascular disease and viral load are linked to myocardial injury and worse outcomes. The vascular response to cytokine production and the interaction between SARS-CoV-2 and...
1 CitationsSource
#1Panagiotis Theofilis (UoA: National and Kapodistrian University of Athens)H-Index: 5
#2Evangelos Oikonomou (UoA: National and Kapodistrian University of Athens)H-Index: 32
Last. Dimitris Tousoulis (UoA: National and Kapodistrian University of Athens)H-Index: 81
view all 9 authors...
Abstract null null Background null Pro-angiogenic microRNA modulation is a potentially attractive approach in the management of peripheral artery disease (PAD). The aim of this systematic review and meta-analysis was to examine the impact of microRNAs involved in the process of angiogenesis on blood flow recovery following hind limb ischemia induction in animal models. null null null Methods null A literature search was performed to identify studies testing the efficacy of microRNA treatment on ...
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#1Akos Koller (NYMC: New York Medical College)H-Index: 70
#2M. Harold Laughlin (MU: University of Missouri)H-Index: 62
Last. Adam Lelbach (Semmelweis University)H-Index: 4
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Regular aerobic exercise (RAEX) elicits several positive adaptations in all organs and tissues of the body, culminating in improved health and well-being. Indeed, in over half a century, many studies have shown the benefit of RAEX on cardiovascular outcome in terms of morbidity and mortality. RAEX elicits a wide range of functional and structural adaptations in the heart and its coronary circulation, all of which are to maintain optimal myocardial oxygen and nutritional supply during increased d...
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#1Marios Sagris (UoA: National and Kapodistrian University of Athens)H-Index: 2
#2Alexios S. Antonopoulos (University of Oxford)H-Index: 28
Last. Dimitris Tousoulis (UoA: National and Kapodistrian University of Athens)H-Index: 81
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Myocardial infarction (MI) among young adults (< 45 years) represents a considerable proportion of the total heart attack incidents. The underlying pathophysiologic characteristics, atherosclerotic plaque features and risk factors profile differ between young and older patients with MI. This review article discusses the main differences between the younger and elderly MI patients as well as the different pathogenic mechanisms underlying the development of MI in the younger. Young patients with M...
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#1Evangelos Oikonomou (UoA: National and Kapodistrian University of Athens)H-Index: 32
#2George Lazaros (UoA: National and Kapodistrian University of Athens)H-Index: 23
Last. M.N. Assimakopoulos (UoA: National and Kapodistrian University of Athens)H-Index: 22
view all 14 authors...
Abstract null null Background null Air pollution is a well-described environmental factor with evidence suggesting a firm association with cardiovascular diseases. The purpose of this study was to determine the association of exposure to gaseous air pollutants on atherosclerosis burden. null null null Methods null 1955 inhabitants of the Corinthia region, aged 40 years or older, underwent clinical and biochemical assessment as well as carotid ultrasonography to evaluate carotid intima-media thic...
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#2Marios SagrisH-Index: 2
Last. Dimitris TousoulisH-Index: 81
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Maintenance of endothelial cell integrity is an important component of human health and disease since the endothelium can perform various functions including regulation of vascular tone, control of hemostasis and thrombosis, cellular adhesion, smooth muscle cell proliferation, and vascular inflammation. Endothelial dysfunction is encompassed by complex pathophysiology that is based on endothelial nitric oxide synthase uncoupling and endothelial activation following stimulation from various infla...
1 CitationsSource
Obesity is a risk factor for heart failure (HF), but its presence among HF patients may be associated with favorable outcomes. We investigated the long-term outcomes across different body mass index (BMI) groups, after cardiac resynchronization therapy (CRT), and whether defibrillator back-up (CRT-D) confers survival benefit. One thousand two-hundred seventy-seven (1,277) consecutive patients (mean age: 67.0 ± 12.7 years, 44.1% women, and mean BMI: 28.3 ± 5.6 Kg/m2) who underwent CRT implantatio...
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#1Marios Sagris (UoA: National and Kapodistrian University of Athens)H-Index: 2
#2Panagiotis Theofilis (UoA: National and Kapodistrian University of Athens)H-Index: 5
Last. Dimitris Tousoulis (UoA: National and Kapodistrian University of Athens)H-Index: 81
view all 9 authors...
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been associated with excess mortality worldwide. The cardiovascular system is the second most common target of SARS-CoV-2, which leads to severe complications, including acute myocardial injury, myocarditis, arrhythmias, and venous thromboembolism, as well as other major thrombotic events because of direct endothelial injury and an excessive systemic inflammatory response. This revi...
1 CitationsSource
#1Stergios Soulaidopoulos (UoA: National and Kapodistrian University of Athens)H-Index: 6
#2Georgia Vogiatzi (UoA: National and Kapodistrian University of Athens)H-Index: 11
Last. Konstantinos Tsioufis (UoA: National and Kapodistrian University of Athens)H-Index: 23
view all 7 authors...
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