Joon Hyung Sohn
Yonsei University
Protein subunitInternal medicineEndocrinologyMolecular biologyVirologyAdipose tissueMeridian (astronomy)EnzymeChemistryProspective cohort studyMesenchymal stem cellATPaseInterferonMetabolic syndromeTiterCancer researchEscherichia coliBiochemistryStereochemistryMedicineBiologyUltrastructure
39Publications
7H-index
163Citations
Publications 44
Newest
#1Seongyup Kim (Yonsei University)H-Index: 5
#2Pil Young Jung (Yonsei University)H-Index: 4
Last. Young Woo Eom (Yonsei University)H-Index: 17
view all 8 authors...
Skeletal muscle satellite cells (SkMSCs) play crucial roles in muscle fiber maintenance, repair, and remodeling; however, it remains unknown if these properties are preserved in cultured SkMSCs. In this study, we investigated the characteristics of cultured SkMSCs and their ability to regulate the activity of M1 macrophages. SkMSCs grew well with an average population doubling time of 26.26 ± 6.85 h during 10 passages (P). At P5, Pax7, MyoD, cluster of differentiation (CD)34, and CD56 were not e...
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#1Young Un Choi (Yonsei University)H-Index: 4
#2Yongdae Yoon (Yonsei University)
Last. Young Woo Eom (Yonsei University)H-Index: 17
view all 10 authors...
Background/aim null Mesenchymal stem cell-based tumor therapy is still limited due to the insufficient secretion of effectors and discrepancies between their in vitro and in vivo efficacy. We investigated whether genetically engineered adipose tissue-derived mesenchymal stem cells (ASCs) overexpressing tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) had inhibitory effects on H460 tumor growth both in vitro and in an H460 xenograft model. null Materials and methods null Geneticall...
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#1Jaesik Shin (Yonsei University)
#2Soon Koo Baik (Yonsei University)H-Index: 42
Last. Young Woo Eom (Yonsei University)H-Index: 17
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BACKGROUND/AIM Genetic manipulation of stem cells using non-viral vectors is still limited due to low transfection efficiency. We investigated whether the DNA-binding cell-permeation peptides (CPP) can enhance the transfection efficiency of non-viral vectors in adipose tissue-derived mesenchymal stem cells (ASCs) and whether ASCs over-expressing TRAIL through CPP can inhibit the growth of glioma U251MG cells in vitro and in vivo. MATERIALS AND METHODS ASCs were genetically engineered to over-exp...
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#1Joon Hyung Sohn (Yonsei University)H-Index: 7
#2Dong Heui Kim (Yonsei University)H-Index: 12
We examined the morphology of fertilized egg and ultrastructures of fertilized egg envelopes of dwarf rainbowfish (Melanotaenia praecox) belong to Melanotaeniidae using light and electron microscopes. The fertilized eggs were spherical with adhesive filament, transparent, demersal, and had a narrow perivitelline space and small oil droplets. The size of fertilized egg was 1.02 ± 0.18 mm (n = 30), and there were two kinds of adhesive filament on the fertilized eggs. The long and thick (diameter 1...
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#1Sung Whan Cha (Yonsei University)H-Index: 1
#2Joon Hyung Sohn (Yonsei University)H-Index: 7
Last. Soon Koo Baik (Yonsei University)H-Index: 3
view all 8 authors...
: BACKGROUND AND AIM: There is no consensus regarding the safe resection margin in hepatocellular carcinoma (HCC). Several studies reported that different gross types require different resection margins. We investigated the changes in the tumor microenvironment (TME) in different gross types of HCC. METHODS: We selected tumor tissue and normal tissue 1 and 2 cm away from the HCC. We analyzed the expression status of TME genes and the correlation between TME genes and the effective resection marg...
1 CitationsSource
#1Jun Namkung (Yonsei University)H-Index: 7
#2Joon Hyung Sohn (Yonsei University)H-Index: 7
Last. Kyu Sang Park (Yonsei University)H-Index: 24
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BACKGROUND: Despite being an anti-obesity hepatokine, the levels of serum angiopoietin-like 6 (ANGPTL6) are elevated in various metabolic diseases. Thus, ANGPTL6 expression may reflect metabolic burden and may have compensatory roles. This study investigated the association between serum ANGPTL6 levels and new-onset metabolic syndrome. METHODS: In total, 221 participants without metabolic syndrome were randomly selected from a rural cohort in Korea. Baseline serum ANGPTL6 levels were measured us...
5 CitationsSource
#1Eun Kyung ChoiH-Index: 1
#2Joon Hyung SohnH-Index: 1
Last. Dong Heui KimH-Index: 12
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: In teleost, the structural characteristics of fertilized egg and egg envelope are very important for classification of genus or species. The structures of fertilized egg and egg envelope from Corydoras adolfoi and Corydoras sterbai, Callichthyidae, Siluriformes in teleost were examined by scanning and transmission electron microscopes to confirm whether these morphological structures have specificities of species and family or not. The fertilized eggs of C. adolfoi and C. sterbai were non-tran...
3 CitationsSource
#1Seong Jin Choi (Yonsei University)H-Index: 5
#2Joon Hyung Sohn (Yonsei University)H-Index: 7
Last. In-Bai Chung (Yonsei University)H-Index: 1
view all 6 authors...
Source
#1Sei Hwan You (Yonsei University)
#2Mee Yon Cho (Yonsei University)
Last. Chang Geol Lee (Yonsei University)H-Index: 29
view all 4 authors...
: Pancreatic radiation effect (PRE) can be a component of gastrointestinal tract (GIT) radiotoxicity. This inter-organ correlation between the GIT and the pancreas was assessed through a rat model. Separate local irradiation to the abdomen and the pelvis was applied concurrently for 8-week-old male Sprague Dawley rats. Abdominal irradiation was categorized into pancreatic shield (PS) and non-pancreatic shield (NPS) irradiation. After 5 Gy and 15 Gy irradiation, the rectal mucosa was analyzed at ...
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#1Jun-Young Lee (Yonsei University)H-Index: 11
#2Jaeseok Kim (Yonsei University)H-Index: 18
Last. Byoung Geun Han (Yonsei University)H-Index: 11
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Objective Malnutrition is very complex in patients with end-stage renal disease (ESRD) and is associated with poor prognosis. This is because hemodynamic changes, hormonal changes, persistent inflammatory reactions, and fluid overloads are more complicated as uremia is worsening. Bio-impedance spectroscopy (BIS) is a useful method to estimate fluid balance (Overhydration/ extracellular water, OH/ECW) and nutritional status (Phase angle, PhA). We aimed to evaluate the volume and nutritional statu...
4 CitationsSource