Tim Large
Indiana University
Internal medicineUrologySurgeryPediatricsEnucleationCalcium oxalateProstateHyperplasiaCloacal exstrophyLower urinary tract symptomsUreteroscopyPercutaneous nephrolithotomyPopulationHolmium laserOlder patientsIn patientPerioperativeMedicineCohortUrinary system
48Publications
6H-index
108Citations
Publications 35
Newest
#1Andre Woloshuk (IU: Indiana University)H-Index: 5
#2Matthew S. Lee (IU: Indiana University)
Last. Tim Large (IU: Indiana University)H-Index: 6
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With increased use of sodium-glucose co-transporter 2 (SGLT2) inhibitors as antidiabetic agents, the risk of serious fungal urinary tract infection (UTI) may be increased. We present the case of a 67-year-old Caucasian female who was admitted for emphysematous pyelitis and found to have a fungal ball in the renal pelvis. Candida glabrata was cultured and the patient was managed with percutaneous nephrostomy tube placement and antifungal treatment. The fungal ball persisted and required surgical ...
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#1Matthew S. Lee (NU: Northwestern University)
#2Mark Assmus (IU: Indiana University)
Last. Amy Krambeck (NU: Northwestern University)H-Index: 1
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PURPOSE To perform a global survey to identify contemporary practice patterns of transurethral therapies for benign prostatic hypertrophy. METHODS A REDCap survey was distributed to the ~ 3500 members of the Endourological Society. Surgeons completed demographic information and then selected the BPH therapies they perform 10 cases/year. There were four categories of BPH therapies: ablation, enucleation, resection/vaporization, and MIST (minimally invasive surgical technique). Within each categor...
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#1Tim Large (IU: Indiana University)H-Index: 6
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#1Tim Large (IU: Indiana University)H-Index: 6
#2Charles U. Nottingham (IU: Indiana University)H-Index: 1
Last. Amy E. Krambeck (IU: Indiana University)H-Index: 53
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INTRODUCTION Currently, there are multiple intracorporeal lithotripters available for use in percutaneous nephrolithotomy (PCNL). This study aimed to evaluate the efficiency of two novel lithotripters; TrilogyTM and ShockPulse-SE. METHODS This is a prospective, multi-institutional, randomized trial comparing outcomes of PCNL using two novel lithotripters between February 2019 and June 2020. The study assessed objective measures of stone clearance time, stone clearance rate, device malfunction, s...
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#1Charles U. Nottingham (WashU: Washington University in St. Louis)
#2Tim Large (IU: Indiana University)H-Index: 6
Last. Amy Krambeck (NU: Northwestern University)H-Index: 1
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INTRODUCTION The purpose of this study was to describe our initial experience of using a newly-optimized Moses technology that is part of the second generation Moses platform specifically designed for holmium laser enucleation of the prostate M2-HoLEP, and compare it to patients undergoing holmium laser enucleation of the prostate (HoLEP) using standard holmium:YAG technology (S-HoLEP). METHODS We retrospectively collected data on patients who underwent M2-HoLEP and compared it to the last 50 pa...
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#1Matthew S. Lee (IU: Indiana University)
#2Mark Assmus (IU: Indiana University)
Last. Amy Krambeck (NU: Northwestern University)H-Index: 1
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Objective To determine the true failure rate of opioid free ureteroscopy (OF-URS) and rates of new-persistent opioid use utilizing a national prescription drug monitoring program (PDMP). Material and Methods We identified 239 patients utilizing our retrospective stone database who underwent OF-URS from Februrary 2018-March 2020. In Feb 2018, we initiated a OF-URS pathway (diclofenac, tamsulosin, acetaminophen, pyridium and oxybutynin). Patients who had a contraindication to NSAIDs were excluded ...
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#1Mark A. Assmus (IU: Indiana University)
#1Mark Assmus (IU: Indiana University)
Last. Amy Krambeck (NU: Northwestern University)H-Index: 1
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BACKGROUND Holmium laser enucleation of the prostate (HoLEP) is a highly effective and durable minimally invasive surgery for benign prostatic hyperplasia. Historically, alternative treatments for large glands (≥175mL) are associated with prolonged length of stay (LOS) and postoperative catheterization. However, advances in laser technology combined with surgical technique optimization have early evidence supporting same day discharge. We look to examine contemporary same day discharge outcomes ...
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#1Jessica J. Saw (Mayo Clinic)H-Index: 3
#2Mayandi Sivaguru (UIUC: University of Illinois at Urbana–Champaign)H-Index: 32
Last. Bruce W. Fouke (UIUC: University of Illinois at Urbana–Champaign)H-Index: 27
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Background: Human kidney stones form via repeated events of mineral precipitation, partial dissolution and reprecipitation, which are directly analogous to similar processes in other natural and man-made environments where resident microbiomes strongly influence biomineralization. High-resolution microscopy and high-fidelity metagenomic (microscopy-to-omics) analyses, applicable to all forms of biomineralization, have been applied to assemble definitive evidence of in vivo microbiome entombment ...
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#1John Ethan Brinkman (IU: Indiana University)
#2Tim Large (IU: Indiana University)H-Index: 6
Last. Amy E. Krambeck (IU: Indiana University)H-Index: 53
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Background: There are multiple stone types, each forming under different urinary conditions. We compared clinical and metabolic findings in pure stone formers to understand if there are consistent factors that differentiate these groups in terms of underlying etiology and potential for empiric treatment. Materials and Methods: Pure SFs based on infrared spectroscopic analysis of stones obtained at our institution between 01/2002 and 07/2018 with a corresponding 24-hour urinalysis were retrospect...
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#1Deepak Agarwal (IU: Indiana University)H-Index: 6
#1Deepak K. Agarwal (IU: Indiana University)H-Index: 1
Last. Amy E. Krambeck (IU: Indiana University)H-Index: 53
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Background: Holmium laser enucleation of the prostate (HoLEP) is a highly effective procedure for benign prostatic hyperplasia that is size independent and has been recommended for patients necessi...
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