Raj C. Shah
Rush University Medical Center
PsychiatryInternal medicineDemographyPsychologyRandomized controlled trialNeuroscienceCognitionPhysical therapyCohort studyHazard ratioAspirinDepression (differential diagnoses)DiseaseDementiaPopulationCognitive declineAlzheimer's diseaseFamily medicineClinical trialMedicineGerontology
Publications 289
#1Jo Wrigglesworth (Monash University)H-Index: 4
#2Nurathifah Yaacob (Monash University)
Last. Sharna D. Jamadar (Monash University)H-Index: 21
view all 14 authors...
Abstract null null Brain age is a neuroimaging-based biomarker of aging. This study examined whether the difference between brain age and chronological age (brain-PAD) is associated with cognitive function at baseline and longitudinally. Participants were relatively healthy, predominantly white community-dwelling older adults (n = 531, aged ≥70 years), with high educational attainment (61% ≥12 years) and socioeconomic status (59% ≥75th percentile). Brain age was estimated from T1-weighted magnet...
#1Zhen ZhouH-Index: 108
#2Joanne RyanH-Index: 35
Last. Mark NelsonH-Index: 59
view all 16 authors...
Background: The neurocognitive effect of statins in older adults remains uncertain. Objectives: To investigate the associations of statin use with cognitive decline and incident dementia among olde...
#1Sara E. Espinoza (University of Texas Health Science Center at San Antonio)H-Index: 20
#2Robyn L. Woods (Monash University)H-Index: 30
Last. Joanne Ryan (Monash University)H-Index: 35
view all 21 authors...
Background null Frailty is associated with chronic inflammation, which may be modified by aspirin. The purpose of this study was to determine whether low dose aspirin reduces incident frailty in healthy older adult participants of the ASPirin in Reducing Events in the Elderly (ASPREE) trial. null Methods null In the U.S and Australia, 19,114 community-dwelling individuals aged ≥70 years (U.S minorities ≥65 years) and free of overt cardiovascular disease, persistent physical disability, and demen...
#1Johanna Joyce (Monash University)H-Index: 1
#2Joanne Ryan (Monash University)H-Index: 35
Last. Rosanne Freak-Poli (Monash University)H-Index: 18
view all 10 authors...
BACKGROUND Poor social health is prevalent in older adults and may be associated with worse cognition, and increased dementia risk. The aim of this study was to determine whether social isolation, social support and loneliness are independently associated with cognitive function and incident dementia over 5 years in older adults, and to investigate potential gender differences. METHODS Participants were 11,498 community-dwelling relatively healthy Australians aged 70-94, in the ASPREE Longitudin...
#1Robyn L. Woods (Monash University)H-Index: 30
#2Sara E. Espinoza (University of Texas Health Science Center at San Antonio)H-Index: 20
Last. Mark Nelson (Menzies Research Institute)H-Index: 59
view all 20 authors...
BACKGROUND Cerebrovascular events, dementia and cancer can contribute to physical disability with activities of daily living (ADL). It is unclear whether low-dose aspirin reduces this burden in aging populations. In a secondary analysis, we now examine aspirin's effects on incident and persistent ADL disability within a primary prevention aspirin trial in community-dwelling older adults. METHODS The ASPREE (ASPirin in Reducing Events in the Elderly) trial of daily 100mg aspirin versus placebo re...
Abstract null null The long-term success of prosthetics greatly relies on the biomechanical/medical properties of the implanted material. Inadequate biocompatibility or poor wear resistance can lead to devastating repercussions including osteolysis, tissue inflammation, and implant failure, which require revisionary surgery, thus being costly and painful for the patient. Therefore, special attention has been given to the modification/treatment of prosthetic surfaces to enhance cell proliferation...
#1Raj C. ShahH-Index: 45
#2Varun KesarH-Index: 4
Last. Paul YeatonH-Index: 28
view all 4 authors...
#1Varun KesarH-Index: 4
#2Raj C. ShahH-Index: 45
Last. Paul YeatonH-Index: 28
view all 6 authors...
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