Xu Xu Bao
Shinshu University
Triple helixUltimate tensile strengthSimulated body fluidBiomedical engineeringElectrospinningComposite materialMaterials scienceBiocompatibilityOsteoblastAgaroseBioactive glassGelatinChitosanType I collagenBone regenerationChemical engineeringTissue engineeringAdhesionScaffoldNanofiber
7Publications
3H-index
68Citations
Publications 7
Newest
#1Chunxia Gao (Shinshu University)H-Index: 4
#2Qiang Gao (Shinshu University)H-Index: 4
Last. Koji Abe (Shinshu University)H-Index: 17
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Mesoporous borosilicate bioactive glass nanofibers consisting of a network of interconnected macropores and mesopores were developed using electrospinning technology combined with a polymer/surfactant cotemplate. The morphology and structure of the nanofibrous scaffolds were studied by scanning electron microscopy, energy-dispersive spectroscopy, Fourier transform infrared spectroscopy, and X-ray diffraction. The morphology and mesoporous structure of the borosilicate glass nanofibers can be adj...
25 CitationsSource
#1Yuan Li (Shinshu University)H-Index: 4
#2Xu Xu Bao (Shinshu University)H-Index: 3
Last. Frank Ko (UBC: University of British Columbia)H-Index: 47
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Fol-8Col is a novel recombinant collagen-like protein incorporated with foldon sequences derived from the native T4 phage fibritin. In this paper, we examined the potential of using Fol-8Col as scaffold for bone tissue engineering. Circular dichroism (CD) spectra indicate that the triple helix structure of Fol-8Col exists at temperatures ranging from 4 to 40 °C. Lactate dehydrogenase assay results and live/death cell staining of osteoblast-like MC3T3-E1 cells, cultivated on Fol-8Col for 24 h, sh...
8 CitationsSource
#1Xu Xu Bao (Shinshu University)H-Index: 3
#2Akira Teramoto (Shinshu University)H-Index: 16
Last. Koji Abe (Shinshu University)H-Index: 17
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Natural bone is a composite mainly made from nano/micro-structure of hydroxyapatite and collagen fibers. For bone regeneration by tissue engineering, it is important to synthesize three dimension nano-composites with good biocompatibility, high bioactivity and great bonding property as potentially useful scaffold. In this study, we fabricated chitosan nano-nonwoven scaffold via electrospinning and modified chitosan scaffolds by carboxymethylation (CM) to improve the osteoconductive characteristi...
2 CitationsSource
#1Xu Xu Bao (Shinshu University)H-Index: 3
#2Ken-ichiro Hayashi (Shinshu University)H-Index: 55
Last. Koji Abe (Shinshu University)H-Index: 17
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Abstract In this study, natural agarose and agar polysaccharides were successfully developed to novel fibrous form for the first time via wet-spinning. Dimethyl sulfoxide (DMSO)/H 2 O = 9:1(v/v) mixture was used as an appropriate solvent which was amenable to the wet-spinning process that produced continuous agarose and agar fibers in ethanol coagulation bath. Results of SEM investigation, swelling ratio and tensile test suggested that the smooth and homogeneous agarose fibers had considerable w...
26 CitationsSource
#1Xu Xu Bao (Shinshu University)H-Index: 3
#2Yuan Li (Shinshu University)H-Index: 4
Last. Koji Abe (Shinshu University)H-Index: 17
view all 4 authors...
Natural bone is a composite mainly made from nano/micro-structure of hydroxyapatite and collagen fibers. For bone regeneration by tissue engineering, it is important to synthesize nano-composites with good biocompatibility, high bioactivity and great bonding property as potentially useful scaffold. In this study, we fabricated chitosan nano-nonwoven scaffold via electrospinning and modified chitosan scaffolds by carboxymethylation (CM). Moreover scaffolds were macerated in SBF (simulated body fl...
3 CitationsSource
#1Yuan Li (Shinshu University)H-Index: 4
#2Naoki Matsuda (Shinshu University)H-Index: 2
Last. Koji Abe (Shinshu University)H-Index: 17
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Functional scaffolds fabricated from biopolymers are of great importance for tissue engineering. In this paper, by mimicking the combination of two major components in Extracellular Matrix – collagen and polysaccharide respectively, we fabricated gelatin and chitosan hybrid sponge for cartilage tissue engineering. Extending previous results of gelatin/chitosan film showed that all the hybrid coating film (chitosan: gelatin= 4:1; 1:1; 1:4) can support the adhesion of ATDC5 that comparable to Tiss...
2 CitationsSource
#1Xu Xu BaoH-Index: 3
Last. Koji AbeH-Index: 17
view all 3 authors...
Bone is a natural composite mainly made from nano/micro-fibers of collagen and hydroxyapatite. In tissue-engineered bone regeneration, it is important to synthesize nano-composite scaffolds with good biocompatibility, high bioactivity, and strong bonding properties. In this study, a chitosan/poly(L-lactic acid) (CS/PLLA) blend of nano/micro fibers were prepared by using electrospinning, to form a three-dimensional porous scaffold for bone regeneration. FT-IR and tensile tests show that we succee...