Hossein Salehi
University of Isfahan
PathologyElectrospinningCellular differentiationAdipose tissueChemistryMaterials scienceMesenchymal stem cellImmunologyRemyelinationGelatinMTT assayStem cellChemical engineeringTissue engineeringCancer researchMedicineBiologyScaffoldNanofiberCell biology
69Publications
19H-index
1,349Citations
Publications 68
Newest
#1Aref Fakhrali (IUT: Isfahan University of Technology)H-Index: 7
#2Mina Nasari (IUT: Isfahan University of Technology)H-Index: 2
Last. Sajjad MohammadiH-Index: 4
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#1Samira Shariati Najafabadi (IUMS: Isfahan University of Medical Sciences)H-Index: 1
#2Noushin Amirpour (IUMS: Isfahan University of Medical Sciences)H-Index: 6
Last. Hossein Salehi (IUMS: Isfahan University of Medical Sciences)H-Index: 19
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Human adipose stem cells (hADSCs) are proper cell sources for tissue regeneration. They mainly mediate their therapeutic effects through paracrine factors as exosomes. The exosomes contents are protein, lipid and RNA. Exosomes are effective in restoring the function of neurons and astrocytes in neurodegenerative diseases, and improve the therapeutic outcomes. We investigated the effect of hADSCs derived exosomes on survival and neural differentiation of PC12 cells in vitro. The isolated hADSCs, ...
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#1Moloud Amini Baghbadorani (IUMS: Isfahan University of Medical Sciences)H-Index: 2
#2Ashkan Bigham (IUMS: Isfahan University of Medical Sciences)H-Index: 14
Last. Hossein Salehi (IUMS: Isfahan University of Medical Sciences)H-Index: 19
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Background: Recently, many studies have been done on the physicochemical properties and biocompatibility of polycaprolactone (PCL) scaffolds containing ceramic reinforcers in the field of bone tissue engineering. In this study, the physical, mechanical and biological properties of electrospined-fabricated PCL scaffolds containing gehlenite (GLN) nanoparticles (NPs) as a novel bioceramic were investigated. Methods: To obtain the appropriate mechanical properties, the solution contains 3%, 5%, 7%,...
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#1Shahram Amini (IUMS: Isfahan University of Medical Sciences)H-Index: 3
#2Hossein Salehi (IUMS: Isfahan University of Medical Sciences)H-Index: 19
Last. Masoud Ghorbani (BMSU: Baqiyatallah University of Medical Sciences)H-Index: 1
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#1Moloud Amini Baghbadorani (IUMS: Isfahan University of Medical Sciences)H-Index: 2
#2Ashkan Bigham (IUMS: Isfahan University of Medical Sciences)H-Index: 1
Last. Hossein Salehi (IUMS: Isfahan University of Medical Sciences)H-Index: 19
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1 CitationsSource
#1Mehnoosh Ashja-Arvan (IUMS: Isfahan University of Medical Sciences)
#2Moein Dehbashi (UI: University of Isfahan)H-Index: 3
Last. Mazdak Ganjalikhani-Hakemi (IUMS: Isfahan University of Medical Sciences)H-Index: 12
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Adipose-derived stem cells (ADSCs) are a subset of mesenchymal stem cells that their therapeutic effects in various diseases make them an interesting tool in cell therapy. In the current study, we aimed to overexpress interferon-beta (IFN-beta) and leukemia inhibitory factor (LIF) cytokines in human ADSCs to evaluate the impact of this overexpression on human ADSCs properties. Here, we designed a construct containing IFN-beta and LIF and then, transduced human adipose-derived stem cells (hADSCs)...
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#1Shahram Amini (IAU: Islamic Azad University)H-Index: 3
#2Ahmad Saudi (IUMS: Isfahan University of Medical Sciences)H-Index: 6
Last. Hossein Salehi (IUMS: Isfahan University of Medical Sciences)H-Index: 19
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Abstract Lignin displays attractive properties in peripheral nerve applications. Here, aligned polycaprolactone (PCL) fibers with various percentages of lignin nanoparticles were fabricated using the electrospinning method. The morphologies, contact angles, mechanical properties, in vitro degradation, and water uptake of the PCL/lignin fibers were characterized. Cell viability and adhesion of PC12 and human adipose-derived stem cells (hADSCs) were studied employing MTT assay and SEM, respectivel...
6 CitationsSource
#1Asma Eslami (IUMS: Isfahan University of Medical Sciences)H-Index: 1
#2Moein Dehbashi (UI: University of Isfahan)H-Index: 3
Last. Mazdak Ganjalikhani-Hakemi (IUMS: Isfahan University of Medical Sciences)H-Index: 12
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Adipose-derived stem cells (ADSCs) are a type of mesenchymal stem cells with the therapeutic effects that make them one of the best sources for cell therapy. In this study, we aimed to assess the ability of human ADSCs for constant expression of IL-11 and IL-13, simultaneously. In this study, the characterized hADSCs were transduced with a lentiviral vector (PCDH-513B) containing IL-11 and IL-13 genes, and the ability of long-term expression of the transgenes was evaluated by ELISA technique on ...
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#1Ahmad Teimourinejad (IUMS: Isfahan University of Medical Sciences)H-Index: 1
Last. Mohammad KazemiH-Index: 27
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Background and purpose : Articular cartilage defects aren’t repaired by itself. Numerous studies have been conducted in the area of cartilage tissue engineering and some of them considered herbal products. An attempt was made in this study to compare the effects of pomegranate fruit extract (PFE), avocado/soybean unsaponifiable (ASU), and their equal proportional mixture on the chondrogenesis of human adipose-derived stem cells (hADSCs). Experimental approach : PFE was prepared through the perco...
1 CitationsSource
#1Aref Fakhrali (IUT: Isfahan University of Technology)H-Index: 7
#2Dariush Semnani (IUT: Isfahan University of Technology)H-Index: 16
Last. Mohammad Ghane (IUT: Isfahan University of Technology)H-Index: 8
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1 CitationsSource