Yohann Bala
AnatomyInternal medicineEndocrinologyBiomedical engineeringComposite materialTomographyBone remodelingChemistryMaterials scienceDentistryOsteoporosisBone mineralBone tissueBone densityCortical boneBone fragilityOrganic matrixBone matrixTrabecular boneMineralization (biology)PorosityMedicine
Publications 61
#1Hari P. Dwivedi (BioMérieux)H-Index: 2
#2Simone Franklin (BioMérieux)H-Index: 1
Last. David H. Pincus (BioMérieux)H-Index: 18
view all 11 authors...
The carbapenem/beta-lactamase inhibitor (meropenem-vaborbactam; MEV) used to treat complicated urinary tract infections and pyelonephritis in adults was approved in 2017 by the U.S. Food and Drug Administration (FDA). We evaluated VITEK 2 MEV (bioMerieux, Durham, NC) compared to the reference broth microdilution (BMD) method. Of 449 Enterobacterales isolates analyzed per FDA/CLSI breakpoints, overall performance was 98.2% Essential Agreement (EA), 98.7% Category Agreement (CA), and 0% Very Major...
#1Emmanuelle Lefevre (AMU: Aix-Marseille University)H-Index: 5
#2Cécile Baron (AMU: Aix-Marseille University)H-Index: 11
Last. Hélène FolletH-Index: 17
view all 9 authors...
Juvenile bone growth is well described (physiological and anatomical) but there are still lacks of knowledge on intrinsic material properties. Our group has already published, on different samples, several studies on the assessment of intrinsic material properties of juvenile bone compared to material properties of adult bone. The purpose of this study was finally to combine different experimental modalities available (ultrasonic measurement, micro-Computed Tomography analysis, mechanical compre...
#2Yohann Bala (BioMérieux)H-Index: 22
Last. Rafael CantónH-Index: 93
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Piperacillin-tazobactam (P/T) is a β-lactam-β-lactamase inhibitor combination frequently used in the hospital setting. ETEST is a gradient diffusion method that represents an alternative to broth microdilution (BMD) for performing antimicrobial susceptibility testing. We conducted a multicentre evaluation of the performance of the new ETEST P/T compared to BMD following FDA and ISO 20776-2 criteria using FDA/CLSI and EUCAST interpretive breakpoints, respectively. A total of 977 isolates (775 Ent...
#1Emmanuelle Lefevre (AMU: Aix-Marseille University)H-Index: 5
#2Delphine Farlay (UCBL: Claude Bernard University Lyon 1)H-Index: 19
Last. Hélène Follet (UCBL: Claude Bernard University Lyon 1)H-Index: 17
view all 10 authors...
Human cortical bone contains two types of tissue: osteonal and interstitial tissue. Growing bone is not well-known in terms of its intrinsic material properties. To date, distinctions between the mechanical properties of osteonal and interstitial regions have not been investigated in juvenile bone and compared to adult bone in a combined dataset. In this work, cortical bone samples obtained from fibulae of 13 juveniles patients (4 to 18 years old) during corrective surgery and from 17 adult dono...
#1Delphine Farlay (University of Lyon)H-Index: 19
#2Yohann Bala (University of Lyon)H-Index: 22
Last. Georges Boivin (University of Lyon)H-Index: 49
view all 7 authors...
Abstract Acceleration of remodeling activity after menopause leads to bone loss and fragility, however, whether this is associated with modifications of bone matrix quality has been less studied. The impact of variation in bone remodeling rate on bone matrix has been studied mainly in pathologies or anti-osteoporotic treatments. However, in healthy women this has been less studied. We analyzed, at the global level, bone matrix quality in bone biopsies from 3 groups of healthy women (20 per group...
Abstract Recent emergence of transferable plasmid-borne colistin resistance (mcr genes) raised fear for pan-resistance. We evaluated the performance of a new chromogenic medium [CHROMID® Colistin R agar (COLR)] for the screening of colistin-resistant Enterobacterales. Specificity was evaluated using 89 rectal swabs and 89 stools prospectively collected. COLR sensitivity was evaluated by seeding 59 negative clinical samples artificially contaminated (105 CFU/mL) with 59 colistin-resistant Enterob...
#1Jean-Gabriel Minonzio (University of Paris)H-Index: 21
#2Nicolas Bochud (University of Paris)H-Index: 12
Last. Pascal Laugier (University of Paris)H-Index: 67
view all 8 authors...
Abstract Several studies showed the ability of the cortex of long bones such as the radius and tibia to guide mechanical waves. Such experimental evidence has given rise to the emergence of a category of quantitative ultrasound techniques, referred to as the axial transmission, specifically developed to measure the propagation of ultrasound guided waves in the cortical shell along the axis of long bones. An ultrasound axial transmission technique, with an automated approach to quantify cortical ...
#6Cécile Olivier (UCBL: Claude Bernard University Lyon 1)H-Index: 8
Interfaces provide the structural basis of essential bone functions. In the hierarchical structure of bone tissue, heterogeneities such as porosity or boundaries are found at scales ranging from nanometers to millimeters, all of which contributing to macroscopic properties. To date, however, the complexity or limitations of currently used imaging methods restrict our understanding of this functional integration. Here we address this issue using label-free third-harmonic generation (THG) microsco...
#1Anais FradetH-Index: 4
#2Mathilde BouchetH-Index: 2
Last. Martine CrosetH-Index: 21
view all 20 authors...
// Anais Fradet 1, 2, * , Mathilde Bouchet 1, 2, * , Carine Delliaux 3, 4 , Manon Gervais 1, 2 , Casina Kan 1, 2 , Claire Benetollo 2, 5 , Francesco Pantano 6 , Geoffrey Vargas 1, 2 , Lamia Bouazza 1, 2 , Martine Croset 1, 2 , Yohann Bala 1, 2 , Xavier Leroy 7 , Thomas J Rosol 8 , Jennifer Rieusset 9 , Akeila Bellahcene 10 , Vincent Castronovo 10 , Jane E Aubin 11 , Philippe Clezardin 1, 2 , Martine Duterque-Coquillaud 3, 4 , Edith Bonnelye 1, 2 1 InsermUMR1033, F-69372 Lyon, France 2 Universite...
#1Yohann Bala (INSA Lyon: Institut national des sciences Appliquées de Lyon)H-Index: 22
#2Emmanuelle Lefevre (AMU: Aix-Marseille University)H-Index: 5
Last. Hélène Follet (University of Lyon)H-Index: 17
view all 8 authors...
Abstract Cortical porosity is a major determinant of bone strength. Haversian and Volkmann׳s canals are׳seen’ as pores in 2D cross-section but fashion a dynamic network of interconnected channels in 3D, a quantifiable footprint of intracortical remodeling. Given the changes in bone remodeling across life, we hypothesized that the 3D microarchitecture of the cortical pore network influences its stiffness during growth and ageing. Cubes of cortical bone of 2 mm side-length were harvested in the di...
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