Hicham Fenniri
Northeastern University
Self-healing hydrogelsBiomedical engineeringNanomaterialsNanoparticleNanotechnologyChemistryNanostructureMaterials scienceCombinatorial chemistrySelf-assemblyNanotubeDrug deliveryRosette (schizont appearance)Self assembledRaman spectroscopyPolymerStereochemistryCrystallographySupramolecular chemistryRosette (botany)
Publications 167
#1Gang Chen (CAS: Chinese Academy of Sciences)
#1Gang Chen (CAS: Chinese Academy of Sciences)H-Index: 1
Last. Jianliang Shen (CAS: Chinese Academy of Sciences)H-Index: 24
view all 8 authors...
Abstract A series of barriers including poor drug solubility, stability, biocompatibility, bioavailability and pharmacokinetics, distribution to normal tissues, hemorheological flow limitations, multidrug resistance (MDR), and metastasis compromise cancer therapeutic effects. Nanotechnologies provide potential solutions to address these problems by taking advantage of distinct mechanisms of action of multiple therapeutics/modalities. In this regard, hybrid nanomaterials hold great promise for tr...
#1Elise Lepeltier (University of Angers)H-Index: 13
#2Vincent Levet (GSK: GlaxoSmithKline)
Last. Yohann Corvis (University of Paris)H-Index: 14
view all 7 authors...
#1Jae-Young Cho (National Research Council)H-Index: 11
#2Pankaj Bhowmik (National Research Council)H-Index: 12
Last. Usha D. HemrazH-Index: 11
view all 8 authors...
Plant genetic engineering offers promising solutions to the increasing demand for efficient, sustainable, and high-yielding crop production as well as changing environmental conditions. The main challenge for gene delivery in plants is the presence of a cell wall that limits the transportation of genes within the cells. Microspores are plant cells that are, under the right conditions, capable of generating embryos, leading to the formation of haploid plants. Here, we designed cationic and fluore...
#1Xuan ZhouH-Index: 22
#2Sara TenaglioH-Index: 1
Last. Lijie Grace ZhangH-Index: 42
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Cartilage damage caused by ageing, repeated overloading, trauma, and diseases can result in chronic pain, inflammation, stiffness, and even disability. Unlike other types of tissues (bone, skin, mu...
10 CitationsSource
#1Prabhat Tripathi (NU: Northeastern University)H-Index: 1
#2Liang Shuai (NU: Northeastern University)H-Index: 1
Last. Meni Wanunu (NU: Northeastern University)H-Index: 38
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Rosette nanotubes (RNTs) are a class of materials formed by molecular self-assembly of a fused guanine-cytosine base (G-C base). An important feature of these self-assembled nanotubes is their precise atomic structure, intriguing for rational design and optimization as synthetic transmembrane porins. Here, we present experimental observations of ion transport across 1.1 nm inner diameter RNT porins (RNTPs) of various lengths in the range of 5 – 200 nm. In a typical experiment, custom lipophilic ...
5 CitationsSource
#1Mohamed Alaa Mohamed (Mansoura University)H-Index: 4
#2Afsoon Fallahi (Wyss Institute for Biologically Inspired Engineering)H-Index: 9
Last. Chong Cheng (SUNY: State University of New York System)H-Index: 34
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Abstract Native tissues orchestrate their functions by complex interdependent cascades of biochemical and biophysical cues that vary spatially and temporally during cellular processes. Scaffolds with well-tuned structural, mechanical, and biochemical properties have been developed to guide cell behavior and provide insight on cell-matrix interaction. However, static scaffolds very often fail to mimic the dynamicity of native extracellular matrices. Stimuli-responsive scaffolds have emerged as po...
34 CitationsSource
#1Yiwen Fan (NU: Northeastern University)H-Index: 4
#2Alexander C Pauer (NU: Northeastern University)H-Index: 1
Last. Hicham Fenniri (NU: Northeastern University)H-Index: 36
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Purpose This work presents the preparation of a nanocomposite of ampicillin-conjugated gold nanoparticles (AuNPs) and self-assembled rosette nanotubes (RNTs), and evaluates its antibacterial properties against two strains of drug-resistant bacteria (Staphylococcus aureus [S. aureus], methicillin-resistant S. aureus [MRSA]).
8 CitationsSource
#1Jessica E. Fitzgerald (NU: Northeastern University)H-Index: 4
#2Jianliang Shen (WMU: Wenzhou Medical College)H-Index: 24
Last. Hicham Fenniri (NU: Northeastern University)H-Index: 36
view all 3 authors...
The development of cross-reactive sensor arrays for volatile organics (electronic noses, e-noses) is an active area of research. In this manuscript, we present a new format for barcoded polymer sensor arrays based on porous polymer beads. An array of nine self-encoded polymers was analyzed by Raman spectroscopy before and after exposure to a series of volatile organic compounds, and the changes in the vibrational fingerprints of their polymers was recorded before and after exposure. Our results ...
3 CitationsSource
#1Min-Chao Liu (Guangdong Pharmaceutical University)H-Index: 6
#2Xiang-Yu Sun (Guangdong Pharmaceutical University)H-Index: 5
Last. Jianliang Shen (CAS: Chinese Academy of Sciences)H-Index: 24
view all 9 authors...
AbstractMultifunctional core-shell nanocarriers based on zinc oxide (ZnO)-gated magnetic mesoporous silica nanoparticles (MMSN) were prepared for cancer treatment through magnetic targeting and pH-...
3 CitationsSource
#1Xuan Zhou (GW: George Washington University)H-Index: 22
#2Timothy Esworthy (GW: George Washington University)H-Index: 10
Last. Lijie Grace ZhangH-Index: 42
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Abstract Osteochondral defects resulting from trauma and/or pathologic disorders are critical clinical problems. The current approaches still do not yield satisfactory due to insufficient donor sources and potential immunological rejection of implanted tissues. 3D printing technology has shown great promise for fabricating customizable, biomimetic tissue matrices. The purpose of the present study is to investigate 3D printed scaffolds with biomimetic, biphasic structure for osteochondral regener...
15 CitationsSource