Oliver H.G. Wilder-Smith
Radboud University Nijmegen
Internal medicineSurgeryNociceptionPhysical therapyStimulationPlaceboPancreatitisPropofolPregabalinNeuropathic painHyperalgesiaVisceral painAnalgesicChronic painQuantitative sensory testingIn patientThreshold of painAnesthesiaElectroencephalographyMedicine
162Publications
48H-index
5,278Citations
Publications 150
Newest
#1Noud van Helmond (Cooper University Hospital)H-Index: 1
#2Hugo M AartsH-Index: 1
Last. Kris Vissers (Radboud University Nijmegen)H-Index: 43
view all 8 authors...
: Persistent postsurgical pain (PPSP) is a common complication of surgery that significantly affects quality of life. A better understanding of which patients are likely to develop PPSP would help to identify when perioperative and postoperative pain management may require specific attention. Quantitative sensory testing (QST) of a patient'fs preoperative pain perception is associated with acute postoperative pain, and acute postoperative pain is a risk factor for PPSP. The direct association be...
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Objective: Pain is a common and disabling symptom in patients with leg ulcers. Clinical quantification of pain mostly depends on subjective pain reports, which do not reveal underlying mechanisms. ...
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#1Noud van Helmond (Radboud University Nijmegen Medical Centre)H-Index: 12
#2Søren Schou OlesenH-Index: 30
Last. Kris Vissers (Radboud University Nijmegen Medical Centre)H-Index: 43
view all 6 authors...
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#1Judith van Vliet (Radboud University Nijmegen)H-Index: 4
#2A.A. Tieleman (Radboud University Nijmegen)H-Index: 8
Last. Oliver H.G. Wilder-Smith (Radboud University Nijmegen)H-Index: 48
view all 7 authors...
Abstract Pain is a common but often ignored symptom in patients with myotonic dystrophy type 2 (DM2). In this explorative study, we assessed qualitative and quantitative aspects of pain in DM2 using 4 questionnaires and quantitative sensory testing. A disease control group (fibromyalgia [FMS]) as well as healthy controls were used to compare the results, because pain in DM2 shows many clinical similarities to pain in FMS. Thirty-four patients with genetically confirmed DM2 (71% female, mean age ...
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#1Hans Timmerman (Radboud University Nijmegen)H-Index: 11
#2Oliver H.G. Wilder-Smith (Radboud University Nijmegen)H-Index: 48
Last. André Wolff (UMCG: University Medical Center Groningen)H-Index: 15
view all 5 authors...
Background: The assessment of a neuropathic pain component (NePC) to establish the neurological criteria required to comply with the clinical description is based on history taking, clinical examination, and quantitative sensory testing (QST) and includes bedside examination (BSE). The objective of this study was to assess the potential association between the clinically diagnosed presence or absence of an NePC, BSE, and the Nijmegen-Aalborg screening QST (NASQ) paradigm in patients with chronic...
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#1Hans Timmerman (Radboud University Nijmegen)H-Index: 11
#2André Wolff (UMCG: University Medical Center Groningen)H-Index: 15
Last. Kris Vissers (Radboud University Nijmegen)H-Index: 43
view all 9 authors...
Background Neuropathic pain is defined as pain caused by a lesion or disease of the somatosensory nervous system and is a major therapeutic challenge. Several screening tools have been developed to help physicians detect patients with neuropathic pain. These have typically been validated in populations pre-stratified for neuropathic pain, leading to a so called “Catch-22 situation:” “a problematic situation for which the only solution is denied by a circumstance inherent in the problem or by a r...
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#1Noud van Helmond (Radboud University Nijmegen)H-Index: 12
#2Hans Timmerman (Radboud University Nijmegen)H-Index: 11
Last. Monique A H Steegers (Radboud University Nijmegen)H-Index: 17
view all 8 authors...
Chronic pain following surgery, persistent postsurgical pain, is an important highly prevalent condition contributing to significant symptom burden and lower quality of life. Persistent postsurgical pain is relatively refractory to treatment hence generating a high need for preventive strategies and treatments. Therefore, the identification of patients at risk of developing persistent pain is an area of active ongoing research. Recently it was demonstrated that peri-operative disruptions in cent...
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#1Hans Timmerman (Radboud University Nijmegen)H-Index: 11
#2Monique A H Steegers (Radboud University Nijmegen)H-Index: 17
Last. Kris Vissers (Radboud University Nijmegen)H-Index: 43
view all 9 authors...
textabstractNeuropathic pain is clinically described as pain caused by a lesion or disease of the somatosensory nervous system. The aim of this study was to assess the validity of the Dutch version of the DN4, in a cross-sectional multicentre design, as a screening tool for detecting a neuropathic pain component in a large consecutive, not pre-stratified on basis of the target outcome, population of patients with chronic pain. Patients’ pain was classified by two independent (pain-)physicians as...
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#1Søren Schou OlesenH-Index: 30
#2Theresa Krauss (TUM: Technische Universität München)H-Index: 1
Last. Asbjørn Mohr DrewesH-Index: 79
view all 7 authors...
Introduction: Chronic pancreatitis (CP) is a disease characterized by inflammation of the pancreas resulting in replacement of the normal functioning parenchyma by fibrotic connective tissue. This process leads to progressively impairment of exocrine and endocrine function and many patients develop a chronic pain syndrome. Objectives: We aimed to characterize the neurobiological signature of pain associated with CP and to discuss its implications for treatment strategies. Methods: Relevant basic...
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#1Noud van HelmondH-Index: 12
#2Hans Timmerman (Radboud University Nijmegen)H-Index: 11
Last. Monique A H Steegers (Radboud University Nijmegen)H-Index: 17
view all 9 authors...
BACKGROUND: Risk factors associated with persistent pain after breast cancer treatment are needed to develop prevention and treatment strategies to improve the quality of life for patients with breast cancer. OBJECTIVES: To identify factors associated with persistent pain in women undergoing breast cancer treatments. STUDY DESIGN: Retrospective study. SETTING: Regional hospital in the Netherlands. METHODS: The primary outcome was pain associated with surgery at more than 6 months postoperatively...
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