Samuel X. Qiu
Chinese Academy of Sciences
CytotoxicityMass spectrometryOrganic chemistryChemistryTwo-dimensional nuclear magnetic resonance spectroscopyIn vitroPetroleum etherBrucea javanicaFlavanoneCajanusKaempferolAntioxidantIsoflavonoidMacelignanLignanGarcinia mangostanaTraditional medicinePrenylationStereochemistryBiology
9Publications
4H-index
45Citations
Publications 9
Newest
#1Nenling Zhang (CAS: Chinese Academy of Sciences)H-Index: 5
#2Xiangchun ShenH-Index: 2
Last. Samuel X. Qiu (CAS: Chinese Academy of Sciences)H-Index: 4
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Two new stilbenoid dimers, cajanstilbenoids A (1) and B (2), were isolated from the leaves of Cajanus cajan. Planar structures of these compounds were verified by NMR (1D and 2D) and high-resolution electrospray ionization mass spectroscopy (HR-ESI–MS). Absolute configurations were assigned by comparing experimental and calculated electronic CD values. The cytotoxicity of 1 and 2 against human hepatoma (HepG2), human breast adenocarcinoma (MCF-7), and human lung cancer (A549) cells were evaluate...
3 CitationsSource
#1Yin-Ning Chen (Xida: Guangxi University)H-Index: 1
#2Heying ZhouH-Index: 1
Last. Riming Huang (CAS: Chinese Academy of Sciences)H-Index: 10
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The phytochemical investigation on the stems of Schisandra bicolor led to the isolation of seven cadinane-type sesquiterpenoids, 2-hydroxy-11,12-dehydrocalamenene (1), ent-T-muurolol (2), (+)-ent-epicubenol (3), (1S,4S)-7,8-dihydroxy-11,12-dehydrocalamenene (4), cadinane-T-cadinol (5), (−)-cadin-4,10(15)-dien-11-oic acid (6), and cadina-4,10(15)-dien-3-one (7). Their structures were determined by extensive analysis of their spectroscopic data. All the isolates were isolated from this species for...
2 CitationsSource
#1Nenling Zhang (CAS: Chinese Academy of Sciences)H-Index: 5
#2Riming Huang (CAS: Chinese Academy of Sciences)H-Index: 10
Last. Samuel X. Qiu (CAS: Chinese Academy of Sciences)H-Index: 4
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A new isoprenylated flavanone, naringenin-3′-isoprenyl-7-methyl ether, was isolated from the chloroform extract of the leaves of Cajanus cajan. Its structure was eluciated by spectral analysis, mainly 1D and 2D NMR.
Source
#1Zhiwei SuH-Index: 4
#2Huijuan HuangH-Index: 3
Last. Samuel X. Qiu (CAS: Chinese Academy of Sciences)H-Index: 4
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Purpose: To investigate the chemical composition and antitumor activity of the petroleum ether extract of the dried ripe fruits of Brucea javanica. Methods: The composition of petroleum ether extract was analyzed by gas chromatography/mass spectrometric (GC/MS) and their antitumor activities were determined by MTT assay. Results: GC/MS spectrometry results indicate that the petroleum ether extract was a mixture of esters, fatty acids, sterides, pregnanones, terpenes, alkaloids, alkenes, alcohols...
10 CitationsSource
#1Yinning Chen (CAS: Chinese Academy of Sciences)H-Index: 1
#2Na Li (CAS: Chinese Academy of Sciences)H-Index: 1
Last. Riming Huang (CAS: Chinese Academy of Sciences)H-Index: 10
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: Further investigation of the stems of Schisandra bicolor led to the isolation of a new dibenzylbutane lignan, named schibicolignan A (1), as well as five known compounds, namely bis[dibenzylbutane] (2), machilin A (3), macelignan (4), saururenin (5) and sphenanlignan (6). The structure of the new lignan was elucidated on the basis of extensive spectroscopic analysis. Antioxidant activity of 1-6 was also evaluated.
3 CitationsSource
#1Manqin Fu (CAS: Chinese Academy of Sciences)H-Index: 3
#2Dun DengH-Index: 1
Last. Samuel X. Qiu (CAS: Chinese Academy of Sciences)H-Index: 4
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One new flavanocoumarin, flemicoumarin A (1) was isolated from the EtOAc-soluble partition of the root of Flemingia philippinensis, along with three known compounds, namely 4,2′-epoxy-4′,5-dihydroxy-7,5′-dimethoxy-3-phenylcoumarin (2), kaempferol 6-C-glucoside (3) and dracocephaloside (4). The structure of compound 1 was elucidated on the basis of its 1D, 2D NMR, CD and MS data. The structures of the known compounds were identified by comparison of their spectroscopic data with those reported in...
5 CitationsSource
#1Ri-Ming Huang (CAS: Chinese Academy of Sciences)H-Index: 2
#2Huijuan Huang (SCNU: South China Normal University)H-Index: 3
Last. Samuel X. Qiu (CAS: Chinese Academy of Sciences)H-Index: 4
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Two new lignans, named zuihonins E (1) and F (2), were isolated from the stems of Schisandra bicolor Cheng var. tuberculata Law. The structures of the new lignans were elucidated on the basis of extensive spectroscopic analysis, including 1D, 2D NMR, and MS experiments, and their absolute stereochemistry was determined by circular dichroism spectrum. Compounds 1 and 2 did not inhibit the growth of hepatoma carcinoma cell (HepG2), lung carcinoma cell (A549), and human breast carcinoma (MCF-7) cel...
4 CitationsSource
#1Manqin Fu (CAS: Chinese Academy of Sciences)H-Index: 2
#2Shixiu Feng (CAS: Chinese Academy of Sciences)H-Index: 3
Last. Samuel X. Qiu (CAS: Chinese Academy of Sciences)H-Index: 4
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A new prenylated isoflavonoid, flemiphilippinin G (1), and a new flavonol glycoside, flemiphilippininside (2), along with eleven known isoflavonoids were obtained from the roots of Flemingia philippinensis (Merr. et Rolfe) Li. Their structures were elucidated on the basis of spectroscopic data. The in vitro cytotoxicities of compounds 1–13 against MCF-7, A549, and Hep-G2 cell lines were determined by using the MTT (=3-(4,5-dimethylthazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide) colorimetric as...
9 CitationsSource
#1Xiaojun Zhou (NCU: Nanchang University)H-Index: 1
#2Riming Huang (CAS: Chinese Academy of Sciences)H-Index: 10
Last. Bin Wang (NCU: Nanchang University)H-Index: 2
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Two new prenylated xanthones (=9H-xanthen-9-ones), garcimangosxanthones D (1) and E (2), together with the six known xanthones 3–8, were isolated from the pericarp of Garcinia mangostana. Their structures were determined by analysis of their spectroscopic data. All of the isolated compounds were biologically evaluated for their in vitro cytotoxic activity against A549, Hep-G2, and MCF-7 human-cancer cell lines and antioxidant activity. Compound 1 exhibited moderate cytotoxicity against Hep-G2 (I...
9 CitationsSource
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