Leontien C. M. Kremer
Utrecht University
CancerInternal medicineSurgeryOncologyIntensive care medicinePediatricsAdverse effectCohort studyAlternative medicineYoung adultAnthracyclineCardiotoxicityMEDLINEGuidelinePopulationChildhood cancerRadiation therapyFamily medicineMedicineCohort
279Publications
52H-index
7,096Citations
Publications 284
Newest
#1Edit Bardi (Boston Children's Hospital)H-Index: 1
#2Renée L. MulderH-Index: 17
Last. Daniel M. Green (St. Jude Children's Research Hospital)H-Index: 57
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Abstract null null Background null Survivors of childhood, adolescent and young adult (CAYA) cancer may develop treatment-induced chronic liver disease. Surveillance guidelines can improve survivors’ health outcomes. However, current recommendations vary, leading to uncertainty about optimal screening. The International Late Effects of Childhood Cancer Guideline Harmonization Group has developed recommendations for the surveillance of late hepatotoxicity after CAYA cancer. null null null Methods...
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#1Elvira C. van DalenH-Index: 28
#2Renée L. MulderH-Index: 17
Last. Eva Frey (Boston Children's Hospital)H-Index: 11
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BACKGROUND Coronary artery disease (CAD) is a concerning late outcome for cancer survivors. However, uniform surveillance guidelines are lacking. AIM To harmonise international recommendations for CAD surveillance for survivors of childhood, adolescent and young adult (CAYA) cancers. METHODS A systematic literature review was performed and evidence graded using the Grading of Recommendations, Assessment, Development and Evaluation criteria. Eligibility included English language studies, a minimu...
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#1Andrea LoH-Index: 10
#2Cécile M. RonckersH-Index: 27
Last. Louis S. Constine (URMC: University of Rochester Medical Center)H-Index: 70
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Purpose null Breast hypoplasia and impaired lactation are poorly studied sequelae of chest radiation therapy (RT) in children. The Pediatric Normal Tissue Effects in the Clinic female breast task force aimed to quantitate the radiation dose-volume effects on these endpoints. null null null Methods and Materials null A literature search was conducted of peer-reviewed manuscripts evaluating breast hypoplasia and lactation after chest RT in children, yielding 789 abstracts. Only 2 studies on childr...
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#1Julianne ByrneH-Index: 20
#2Irene Schmidtmann (University of Mainz)H-Index: 25
Last. Eva Frey (Boston Children's Hospital)H-Index: 11
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Late mortality of European five-year survivors of childhood or adolescent cancer has dropped over the last 60 years, but excess mortality persists. There is little information concerning secular trends in cause-specific mortality among older European survivors. PanCareSurFup pooled data from 12 cancer registries and clinics in 11 European countries from 77 423 five-year survivors of cancer diagnosed before age 21 between 1940 to 2008 followed for an average age of 21 years and a total of 1.27 mi...
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#2Linda BroerH-Index: 36
Last. Dorine BrestersH-Index: 24
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Background: Female childhood cancer survivors (CCSs) carry a risk of therapy-related gonadal dysfunction. Alkylating agents (AA) are well-established risk factors, yet inter-individual variability in ovarian function is observed. Polymorphisms in CYP450 enzymes may explain this variability in AA-induced ovarian damage. We aimed to evaluate associations between previously identified genetic polymorphisms in CYP450 enzymes and AA-related ovarian function among adult CCSs. Methods: Anti-Mullerian h...
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#2Renée L. MulderH-Index: 17
Last. Sue C. Kaste (St. Jude Children's Research Hospital)H-Index: 63
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Childhood, adolescent, and young adult cancer survivors are at increased risk of reduced bone mineral density. Clinical practice surveillance guidelines are important for timely diagnosis and treatment of these survivors, which could improve bone mineral density parameters and prevent fragility fractures. Discordances across current late effects guidelines necessitated international harmonisation of recommendations for bone mineral density surveillance. The International Late Effects of Childhoo...
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Last. AA Eduard Verhagen (Boston Children's Hospital)H-Index: 1
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The organization of multidisciplinary team meetings (MTMs) has become standard practice in pediatric oncology and is widely felt to improve communication, knowledge, and patient care. Although the impact of MTMs on survival in adult oncology has been extensively researched, the potential benefits of survival for pediatric cancer patients are still unclear. This systematic review aimed to examine the impact of MTMs on survival in pediatric oncology settings. Relevant studies were identified by se...
1 CitationsSource
Last. Riccardo Haupt (Istituto Giannina Gaslini)H-Index: 44
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Abstract null null Background null Long-term follow-up (LTFU) care for childhood, adolescent, and young adult (CAYA) cancer survivors is essential to preserve health and quality of life (QoL). Evidence-based guidelines are needed to inform optimal surveillance strategies, but many topics are yet to be addressed by the International Late Effects of Childhood Cancer Guideline Harmonization Group (IGHG). Therefore, the PanCareFollowUp Recommendations Working Group collaborated with stakeholders to ...
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Last. Cecilia Follin (Lund University)H-Index: 12
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Abstract null null Background null The majority of childhood cancer survivors are at risk of treatment-related adverse health outcomes. Survivorship care to mitigate these late effects is endorsed, but it is not available for many adult survivors of childhood cancer in Europe. The PanCareFollowUp project was initiated to improve their health and quality of life (QoL) by facilitating person-centred survivorship care. null null null Methods null The PanCareFollowUp consortium was established in 20...
3 CitationsSource