Ester Mazzola
University of Milan
EpidemiologyOutbreakInternal medicineIncubation periodVirologyRetrospective cohort studyRefugeePediatricsAmikacinMycobacterium tuberculosisDiseaseMycobacterium tuberculosis complexLatent tuberculosisMycobacteriumTuberculosis diagnosisTuberculosisPopulationHuman immunodeficiency virus (HIV)Extrapulmonary tuberculosisIncidence (epidemiology)Family medicineMedicineMicrobiologyEnvironmental health
Publications 20
#1Maria Antonello (University of Milan)H-Index: 4
#2Rossana Scutari (University of Rome Tor Vergata)H-Index: 6
Last. L. Colagrossi (Boston Children's Hospital)H-Index: 5
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Background: Rapid and reliable diagnosis of tuberculosis (TB) represents a diagnostic challenge in compartmentalized extrapulmonary TB infection, because of the small number of mycobacteria (MTB) and the frequently lack of fresh samples to perform culture. Here, we estimate the performances of home-made ddPCR-based assays against culture in 89 biopsies for those fresh and formalin-fixed and paraffin-embedded (FFPE) subsamples were available. Methods: MTB diagnosis in fresh subsamples was perform...
#1Ester OlivaH-Index: 1
#2Marco ArosioH-Index: 3
Last. Claudio FarinaH-Index: 8
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Rapid and accurate identification of non-tuberculous mycobacteria (NTM) is important for a prompt start to antibiotic therapy. The aim of this study was to obtain accurate identification of NTM quickly by analyzing the performance of the MALDI-TOF mass spectrometry (MS) system VITEK® MS in identifying various NTM species from solid medium and MGIT 960 liquid medium. The study was performed in two phases: preliminary and perspective. Overall, 41/42 species and 33/34 species were correctly identif...
#1Niccolò Riccardi (UniGe: University of Genoa)H-Index: 15
#2Maurizio FerrareseH-Index: 16
Last. Luigi CodecasaH-Index: 26
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Objective:To describe a left epididymitis and para-aortical involvement caused by Mycobacterium tuberculosis hominis reactivation after bacillus Calmette-Guerin instillation for non-muscle-invasive...
#1Marino FacciniH-Index: 11
#2Antonio RussoH-Index: 103
Last. Maria Luisa Ricci (ISS: Istituto Superiore di Sanità)H-Index: 16
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In July 2018, a large outbreak of Legionnaires’ disease (LD) caused by Legionella pneumophila serogroup 1 (Lp1) occurred in Bresso, Italy. Fifty-two cases were diagnosed, including five deaths. We performed an epidemiological investigation and prepared a map of the places cases visited during the incubation period. All sites identified as potential sources were investigated and sampled. Association between heavy rainfall and LD cases was evaluated in a case-crossover study. We also performed a c...
#1Valeria Cento (University of Milan)H-Index: 21
#2Alice NavaH-Index: 1
Last. Ester MazzolaH-Index: 8
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Abstract Objectives Mycobacterium xenopi (M. xenopi) is a non-tubercolar mycobacterium (NTM) whose clinical diagnosis and drug-sensitivity studies are frequently hampered by poor in vitro growth. Extending culture incubation from 42 (common-standard) to 56 days could improve chances of diagnosis, and provide strains for phenotypic drug-sensitivity profiling of this poorly studied, but clinically-relevant mycobacterium. Methods Time-to-positivity (TTP) of mycobacteria-cultures, incubated for 56 d...
#1Simone Villa (Health Science University)H-Index: 8
#2Luigi CodecasaH-Index: 26
Last. Mario Carlo Raviglione (Health Science University)H-Index: 6
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These two experiences emphasise the urgency of data sharing and common policies when addressing TB prevention and care in a highly mobile population in countries of first arrival and final destination
#1Stefano Aliberti (University of Milan)H-Index: 52
#2Giovanni Sotgiu (University of Sassari)H-Index: 70
Last. Francesco Blasi (University of Milan)H-Index: 125
view all 15 authors...
Abstract Outcome recognition is a crucial step in the management of non-tuberculous mycobacteria lung disease (NTM-LD). In order to explore NTM-LD outcomes in a real-life setting, an observational, retrospective study enrolling consecutive adults who received treatment for NTM-LD in Milan, Italy, from 2007 to 2017 was conducted. Among 170 patients (68.2% females; median age: 68 years), NTM-LD was mainly due to M. avium complex (MAC) (71.2%), M. kansasii (9.4%) and M. xenopi (7.1%). Along a media...
#1Simone Villa (University of Milan)H-Index: 8
#2Luigi CodecasaH-Index: 26
Last. Mario Raviglione (University of Milan)H-Index: 106
view all 13 authors...
In countries of the European Union, tuberculosis (TB) mainly affects marginalised people, including asylum seekers. Migratory flows from high-incidence countries to Italy have increased up to 2017, posing challenges to the national health system. This study sought to assess TB and latent TB infection (LTBI) prevalence among asylum seekers in Milan during the biennium 2016–2017 and to evaluate interventions in place. A two-level active surveillance and screening system was developed for both TB a...
#1Stefano AlibertiH-Index: 52
#2Giovanni SotgiuH-Index: 70
Last. Francesco BlasiH-Index: 125
view all 15 authors...
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