Mark W. J. Strachan
Western General Hospital
Internal medicineEndocrinologySurgeryCardiologyCognitionPediatricsType 2 diabetesFatty liverDiseaseInsulinDementiaHypoglycemiaType 1 diabetesPopulationType 2 Diabetes MellitusCognitive declineDiabetes mellitusMedicineCohortGerontologyGastroenterology
165Publications
46H-index
5,330Citations
Publications 165
Newest
#1Evgenia Foteinopoulou (Western General Hospital)H-Index: 1
#2Catriona Clarke (Western General Hospital)H-Index: 6
Last. Mark W. J. Strachan (Western General Hospital)H-Index: 46
view all 10 authors...
Aims/hypothesis The aim of this study was to determine the impact of the routine use of serum C-peptide in an out-patient clinic setting on individuals with a clinician-diagnosis of type 1 diabetes. Methods In this single centre study, individuals with type 1 diabetes of at least 3 years duration were offered random serum C-peptide testing at routine clinic review. A C-peptide ≥200 pmol/L prompted further evaluation of the individual using a diagnostic algorithm that included measurement of isle...
1 CitationsSource
#1Emmanuel Sandoval-Garcia (Edin.: University of Edinburgh)
#2Stela McLachlan (Edin.: University of Edinburgh)H-Index: 25
Last. Jackie F. Price (Edin.: University of Edinburgh)H-Index: 62
view all 7 authors...
Our aim was to determine whether quantitative retinal traits in people with type 2 diabetes are independently associated with incident major cardiovascular events including CHD and stroke. A total of 1066 men and women with type 2 diabetes, aged 65–74 years, were followed up over 8 years in the population-based Edinburgh Type 2 Diabetes Study. Using retinal photographs taken at baseline and specialist software, a number of quantitative retinal traits were measured, including arteriolar and venul...
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#1Göher Ayman (University of Oxford)
#2James A Strachan (John Radcliffe Hospital)
Last. Marian Knight (University of Oxford)H-Index: 65
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AIMS To undertake a Priority Setting Partnership (PSP) to establish priorities for future research in diabetes and pregnancy, according to women with experience of pregnancy, and planning pregnancy, with any type of diabetes, their support networks and healthcare professionals. METHODS The PSP used established James Lind Alliance (JLA) methodology working with women and their support networks and healthcare professionals UK-wide. Unanswered questions about the time before, during or after pregna...
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#1Anna R. DoverH-Index: 11
#2Mark W. J. Strachan (Western General Hospital)H-Index: 46
Last. Fraser W. Gibb (Edin.: University of Edinburgh)H-Index: 13
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AIMS Intensive glycaemic control is associated with substantial health benefits in people with type 1 diabetes. We sought to examine clinical and demographic factors associated with meeting glycaemic targets in type 1 diabetes. METHODS We conducted a cross-sectional analysis of 4594 individuals with type 1 diabetes. The primary outcome of the study was assessing factors associated with meeting HbA1c targets. Secondary endpoints included factors associated with continuous subcutaneous insulin inf...
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#1Kathryn LintonH-Index: 1
#2Roland H Stimson (Edin.: University of Edinburgh)H-Index: 22
Last. Fraser W. Gibb (Edin.: University of Edinburgh)H-Index: 13
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Background:Early worsening of diabetic retinopathy (EWDR) was observed in the intensively treated arm of the Diabetes Control and Complications Trial (DCCT) before long-term benefits accrued. We so...
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#1Sheila M. Grecian (Edin.: University of Edinburgh)H-Index: 2
#2Stela McLachlan (Edin.: University of Edinburgh)H-Index: 25
Last. Mark W. J. Strachan (Western General Hospital)H-Index: 46
view all 13 authors...
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#1Evgenia Foteinopoulou (Western General Hospital)H-Index: 1
#2Mark W. J. Strachan (Western General Hospital)H-Index: 46
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#1Anita JeyamH-Index: 3
#2Helen M. ColhounH-Index: 79
Last. Paul M. McKeigueH-Index: 75
view all 16 authors...
The authors report that the following errors occurred in transcribing the results of the statistical computations into the abstract and text. In the Abstract, “insulin dose at …
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#1Alistair L. Carr (Edin.: University of Edinburgh)
#2Anniek J. Sluiman (Edin.: University of Edinburgh)H-Index: 1
Last. Jackie F. Price (Edin.: University of Edinburgh)H-Index: 62
view all 7 authors...
Aims/hypothesis We aimed to determine the association of depression with dementia risk in people with type 2 diabetes, and to explore the possible mediating role of inflammation in this relationship. Methods The Edinburgh Type 2 Diabetes Study is a prospective cohort of 1066 men and women with type 2 diabetes aged 60-75 years. Cox proportional hazards regression analysis was used to investigate the association between depression, assessed at baseline, and subsequent risk of dementia over 10 year...
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#1Anita Jeyam (Western General Hospital)H-Index: 3
#2Helen M. Colhoun (Western General Hospital)H-Index: 79
view all 16 authors...
OBJECTIVE To quantify the relationship of residual C-peptide secretion to glycemic outcomes and microvascular complications in type 1 diabetes. RESEARCH DESIGN AND METHODS C-peptide was measured in an untimed blood sample in the Scottish Diabetes Research Network Type 1 Bioresource (SDRNT1BIO) cohort of 6,076 people with type 1 diabetes monitored for an average of 5.2 years. RESULTS In regression models adjusted for age at onset and duration, effect sizes for C-peptide ≥200 vs. CONCLUSIONS These...
5 CitationsSource