Cesar A. Moran
University of Texas MD Anderson Cancer Center
CancerInternal medicineRadiologyPathologyOncologyImmunohistochemistryBiopsyLung cancerThymic carcinomaCarcinomaLungCytokeratinMediastinumThymomaMalignancyDifferential diagnosisAdenocarcinomaCancer researchMedicineBiology
460Publications
76H-index
12.9kCitations
Publications 454
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#1Cesar A. Moran (University of Texas MD Anderson Cancer Center)H-Index: 76
Over the last years, a number of changes has taken place in the evaluation of thymomas. More recently, the introduction of a TNM staging system in the assessment of thymic epithelial tumors, in general, has been put forward. Important to highlight is that this TNM system is not based on tumor size, and because of that shortcoming, it was in need to borrow most if not all of the information from the experience derived from other schemas that over the years have been tested with larger series of c...
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#1Diana M. Oramas (University of Texas MD Anderson Cancer Center)H-Index: 1
#2Cesar A. MoranH-Index: 76
The interpretation of biopsy specimens in the diagnosis of thymoma is a subject that is generally not addressed in the literature. Even though the diagnosis of thymoma may seem to be an easy step in the assessment of these tumors, in reality, it is the biopsy specimen interpretation that will be use to determine course of action in any particular patient. It may determine whether a patient is a surgical candidate or on the contrary whether a patient may be benefited the most by medical therapy. ...
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#1Cesar A. Moran (University of Texas MD Anderson Cancer Center)H-Index: 76
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#1Diana M. Oramas (University of Texas MD Anderson Cancer Center)H-Index: 1
#2Cesar A. Moran (University of Texas MD Anderson Cancer Center)H-Index: 76
ABSTRACT null null Over the years the nomenclature of thymomas has been debated regarding the best manner in which these tumors should be grouped. In every schema presented thus far, the main issue has been the presence or lack of lymphocytes and accordingly, the tumors have been place into a specific category. However, even though this concepts applies for most of the cases, there are numerous tumors that do not necessarily fit into those categories as either the thymomas show another cellular ...
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#1Diana M. Oramas (University of Texas MD Anderson Cancer Center)H-Index: 1
#2Cesar A. Moran (University of Texas MD Anderson Cancer Center)H-Index: 76
ABSTRACT null null Cystic lesions of the anterior mediastinum represent a well-known group of benign lesions that are relatively common in the general practice, namely in the pediatric age group. In the adult population, multilocular thymic cyst (MTC) plays an important role in occurrence as it presents as a cystic anterior mediastinal mass that clinically may mimic another anterior mediastinal tumor. In general, MTC is of rather unusual occurrence and its histopathological features have been we...
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#1Ydamis Estrella Perez (University of Texas MD Anderson Cancer Center)
#2Cesar A. Moran (University of Texas MD Anderson Cancer Center)H-Index: 76
ABSTRACT null null A fundamental aspect that is commonly overlook when assessing thymic tumors is the normal histology and immunohistochemical features of the normal thymus. Given the fact that most epithelial tumors occur in the adult population, it is only rarely that we are confronted with assessing normal immunohistochemistry of the thymus. However, we consider that such knowledge is of utmost importance is assessing pathological conditions including epithelial tumors or tumors of other line...
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#1Diana M. Oramas (University of Texas MD Anderson Cancer Center)H-Index: 1
#2Cesar A. Moran (University of Texas MD Anderson Cancer Center)H-Index: 76
Twenty-five cases of micronodular thymomas with prominent cystic changes are presented. The patients are 13 men and 12 women between the ages of 38 and 69 years. Clinically, the majority of patients presented with nonspecific symptoms of cough, chest pain, and dyspnea. Four patients were asymptomatic. Diagnostic imaging showed the presence of an anterior mediastinal mass and surgical resection of the tumor mass was performed in all the patients. Histologically, all the tumors were characterized ...
2 CitationsSource
#1Michael Zaleski (University of Texas MD Anderson Cancer Center)H-Index: 1
#2Neda Kalhor (University of Texas MD Anderson Cancer Center)H-Index: 36
Last. Cesar A. Moran (University of Texas MD Anderson Cancer Center)H-Index: 76
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Thymic typical and atypical carcinoids are rare and appear to be more aggressive than similar tumors in other sites. We retrospectively analyzed a group of biomarkers that hold therapeutic and prognostic utility, in 27 of these tumors. All cases were immunohistochemically stained with PAX5, MET, CRMP5, paxillin, p21, p27, EZH2, PDL-1, and Ki-67, and then H-scored. Clinicopathologic and survival data were statistically analyzed against staining (χ2 test). Five- and 10-year-survival rates were 53%...
2 CitationsSource
#1Diana M. Oramas (University of Texas MD Anderson Cancer Center)H-Index: 1
#2Michael Zaleski (University of Texas MD Anderson Cancer Center)H-Index: 1
Last. Cesar A. Moran (University of Texas MD Anderson Cancer Center)H-Index: 76
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Sixty-four cases of sarcomatoid pleural mesothelioma represent the basis of this study. The patients are 51 men and 13 women between the ages of 42 and 79 years, who presented with symptoms of chest pain, cough, and weight loss. Diagnostic imaging showed the presence of diffuse pleural thickening with encasement of the lung parenchyma in all the cases. All patients had surgical resection via extrapleural pneumonectomy. By immunohistochemistry, all cases were positive for cytokeratin AE1/AE3; how...
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#1Carmen BehrensH-Index: 68
#2Pedro RochaH-Index: 5
Last. Ignacio I. Wistuba (University of Texas MD Anderson Cancer Center)H-Index: 115
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Abstract Introduction Immune infiltration in lung adenocarcinomas (LUADs) has been associated with response to immune checkpoint inhibitors. Clinical features underlying differential responses of patients with LUAD to immunotherapy are not well understood. Here, we analyzed the association between LUAD immune infiltration with clinicopathological variables. Material and Methods Intratumoral CD3, CD8, and CD68 cell densities (tumor-associated immune cells [TAICs]) were immunohistochemically asses...
1 CitationsSource