Giuseppina Sandri
University of Pavia
Penetration (firestop)BiophysicsBiomedical engineeringNuclear chemistryChemistryMaterials scienceBuccal administrationSolid lipid nanoparticlePlatelet lysateBiocompatibilityChitosanDrug deliveryMucoadhesionWound healingChemical engineeringChromatographyPolymerMedicineDosage formPharmacology
189Publications
35H-index
3,590Citations
Publications 133
Newest
#1Barbara ViganiH-Index: 14
#2Caterina ValentinoH-Index: 1
Last. Franca FerrariH-Index: 38
view all 11 authors...
Glioblastoma multiforme (GBM) is one of the most prevalent and aggressive brain tumors for which there is currently no cure. A novel composite nanosystem (CN), consisting of chitosan-coated Solid Lipid Nanoparticles (c-SLN) embedded in O-carboxymethyl chitosan (O-CMCS)-containing nanofibers (NFs), was proposed as a potential tool for the local delivery of lipophilic anti-proliferative drugs. Coacervation was selected as a solvent-free method for the preparation of stearic acid (SA) and behenic a...
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#1Barbara ViganiH-Index: 14
#2Caterina ValentinoH-Index: 1
Last. Franca FerrariH-Index: 38
view all 11 authors...
Injuries to the nervous system affect more than one billion people worldwide, and dramatically impact on the patient’s quality of life. The present work aimed to design and develop a gellan gum (GG)-based composite system for the local delivery of the neuroprotective sigma-1 receptor agonist, 1-[3-(1,1′-biphen)-4-yl] butylpiperidine (RC-33), as a potential tool for the treatment of tissue nervous injuries. The system, consisting of cross-linked electrospun nanofibers embedded in a RC-33-loaded f...
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#1Mária Budai-Szűcs (University of Szeged)H-Index: 12
#2Marco Ruggeri (UNIPV: University of Pavia)H-Index: 5
Last. Franca Ferrari (UNIPV: University of Pavia)H-Index: 38
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Periodontitis is a set of inflammatory conditions affecting the tissues surrounding the teeth predominantly sustained by bacterial infections. The aim of the work was the design and the development of scaffolds based on biopolymers to be inserted in the periodontal pocket to restore tissue integrity and to treat bacterial infections. Nanofibrous scaffolds were prepared by means of electrospinning. Gelatin was considered as base component and was associated to low and high molecular weight chitos...
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#1Eleonora Bianchi (UNIPV: University of Pavia)H-Index: 1
#2Marco Ruggeri (UNIPV: University of Pavia)H-Index: 5
Last. Franca Ferrari (UNIPV: University of Pavia)H-Index: 38
view all 8 authors...
The tendon is a highly aligned connective tissue that transmits force from muscle to bone. Each year, more than 32 million tendon injuries have been reported, in fact, tendinopathies represent at least 50% of all sports injuries, and their incidence rates have increased in recent decades due to the aging population. Current clinical grafts used in tendon treatment are subject to several restrictions and there is a significant demand for alternative engineered tissue. For this reason, innovative ...
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#1Mariana P. Figueiredo (USP: University of São Paulo)H-Index: 2
#2Ana Borrego-Sánchez (UGR: University of Granada)H-Index: 9
Last. Vera R. L. Constantino (USP: University of São Paulo)H-Index: 29
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#1Dalila Miele (UNIPV: University of Pavia)H-Index: 5
#2Laura Catenacci (UNIPV: University of Pavia)H-Index: 18
Last. Maria Cristina Bonferoni (UNIPV: University of Pavia)H-Index: 43
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Collagen, thanks to its biocompatibility, biodegradability and weak antigenicity, is widely used in dressings and scaffolds, also as electrospun fibers. Its mechanical stability can be improved by adding polycaprolactone (PCL), a synthetic and biodegradable aliphatic polyester. While previously collagen/PCL combinations were electrospun in solvents such as hexafluoroisopropanol (HFIP) or trifluoroethanol (TFE), more recently literature describes collagen/PCL nanofibers obtained in acidic aqueous...
1 CitationsSource
Last. César ViserasH-Index: 34
view all 7 authors...
1 CitationsSource
#1Barbara ViganiH-Index: 14
#2Silvia RossiH-Index: 36
Last. Franca FerrariH-Index: 38
view all 6 authors...
In situ gelling drug delivery systems have gained enormous attention over the last decade. They are in a sol-state before administration, and they are capable of forming gels in response to different endogenous stimuli, such as temperature increase, pH change and the presence of ions. Such systems can be administered through different routes, to achieve local or systemic drug delivery and can also be successfully used as vehicles for drug-loaded nano- and microparticles. Natural, synthetic and/o...
2 CitationsSource
#1Marco RuggeriH-Index: 5
#2Eleonora BianchiH-Index: 1
Last. Franca FerrariH-Index: 38
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Chronic wounds, such as pressure ulcers, diabetic ulcers, venous ulcers and arterial insufficiency ulcers, are lesions that fail to proceed through the normal healing process within a period of 12 weeks. The treatment of skin chronic wounds still represents a great challenge. Wound medical devices (MDs) range from conventional and advanced dressings, up to skin grafts, but none of these are generally recognized as a gold standard. Based on recent developments, this paper reviews nanotechnology-b...
2 CitationsSource
#1Fátima García-Villén (UGR: University of Granada)H-Index: 9
#2Angela Faccendini (UNIPV: University of Pavia)H-Index: 8
Last. Giuseppina Sandri (UNIPV: University of Pavia)H-Index: 35
view all 10 authors...
Background: hydrogels prepared with natural inorganic excipients and spring waters are commonly used in medical hydrology. Design of these clay-based formulations continues to be a field scarcely addressed. Safety and wound healing properties of different fibrous nanoclay/spring water hydrogels were addressed. Methods: in vitro biocompatibility, by means of MTT assay, and wound healing properties were studied. Confocal Laser Scanning Microscopy was used to study the morphology of fibroblasts dur...
5 CitationsSource