Maria Rosário Domingues
University of Aveiro
EndocrinologyRadicalMass spectrometryOrganic chemistryChemistryElectrosprayAntioxidantPhospholipidLipidomePhosphatidylethanolamineCardiolipinTandem mass spectrometryFood scienceElectrospray ionizationChromatographyLipid metabolismFatty acidBiochemistryLipidomicsBiology
Publications 115
#1Diana Madeira (Université du Québec)H-Index: 18
#2Joana Fernandes (University of Aveiro)H-Index: 1
Last. Ricardo Calado (University of Aveiro)H-Index: 33
view all 7 authors...
Abstract (249 words) Extreme weather events, such as heatwaves, are becoming increasingly frequent, long-lasting and severe as global climate change continues, shaping marine biodiversity patterns worldwide. Increased risk of overheating and mortality across major taxa have been recurrently observed, jeopardizing the sustainability of ecosystem services. Molecular responses of species, which scale up to physiological and population responses, are determinant processes that modulate species sensi...
1 CitationsSource
#1Christina Savva (KI: Karolinska Institutet)H-Index: 4
#2Luisa A. Helguero (University of Aveiro)H-Index: 26
Last. Marion Korach-André (KI: Karolinska Institutet)H-Index: 15
view all 11 authors...
The prevalence of overweight and obesity among children has drastically increased during the last decades and maternal obesity has been demonstrated as one of the ultimate factors. Nutrition-stimulated transgenerational epigenetic regulation of key metabolic genes is fundamental to the developmental origins of the metabolic syndrome. Fetal nutrition may differently influence female and male offspring. In this work, we investigated the sex-dependent programming of maternal obesity in visceral, su...
#1Lisete M. Silva (Imperial College London)H-Index: 10
#2Viviana G. Correia (University of Lisbon)H-Index: 4
Last. Angelina S. Palma (Imperial College London)H-Index: 22
view all 15 authors...
Abstract The structural diversity of the lipopolysaccharides (LPSs) from Helicobacter pylori poses a challenge to establish accurate and strain-specific structure-function relationships in interactions with the host. Here, LPS structural domains from five clinical isolates were obtained and compared with the reference strain 26695. This was achieved combining information from structural analysis (GC-MS and ESI-MSn) with binding data after interrogation of a LPS-derived carbohydrate microarray wi...
#1Christina SavvaH-Index: 4
Last. Marion Korach-AndréH-Index: 2
view all 7 authors...
#1Diana LopesH-Index: 7
#2Tânia MeloH-Index: 15
Last. Maria Rosário DominguesH-Index: 27
view all 10 authors...
4 CitationsSource
#1Fabio Santos (University of Aveiro)H-Index: 1
#2João P. Monteiro (University of Aveiro)H-Index: 14
Last. Maria Rosário Domingues (University of Aveiro)H-Index: 27
view all 7 authors...
Brown seaweeds are known to present components with appealing bioactive properties eliciting great interest for industrial applications. However, their lipid content is generally disregarded beyond their fatty acid (FA) composition. This study thoroughly characterized the lipid profile of two brown seaweeds collected from Portuguese coast, the native Bifurcaria bifurcata and the invasive Sargassum muticum species, and bioprospecting for antioxidant activity. An integrated state-of-the-art approa...
1 CitationsSource
#1Marco Custódio (University of Aveiro)H-Index: 4
#2Elisabete Maciel (University of Aveiro)H-Index: 16
Last. Ricardo Calado (University of Aveiro)H-Index: 33
view all 5 authors...
Halophytes are increasingly regarded as suitable extractive species and co-products for coastal Integrated Multi-Trophic Aquaculture (IMTA) and studying their lipidome is a valid means towards their economic valorization. Halimione portulacoides (L.) Aellen edible leaves are rich in functional lipids with nutraceutical and pharmaceutical relevance and the present study aimed to investigate the extent to which its lipidome remains unchanged under a range of dissolved inorganic nitrogen (N) and ph...
#1Deolinda Santinha (University of Aveiro)H-Index: 7
#2Anna Klopot (KI: Karolinska Institutet)H-Index: 1
Last. Luisa A. Helguero (University of Aveiro)H-Index: 26
view all 14 authors...
Abstract Liver X receptor (LXR) agonists have the potential to alleviate obesity related diseases, particularly atherosclerosis. However, LXRs are transcriptional regulators that induce de novo lipogenesis and lipid accumulation in hepatocytes which represents a serious adverse effect. In this work, we sought to characterize the LXR agonist GW3965 effects on fatty acid (FA) and phospholipid (PL) remodelling and the correlation with gene expression in order to better understand the underlying eff...
2 CitationsSource
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