Marivalda M. Pereira
Universidade Federal de Minas Gerais
Simulated body fluidComposite materialAlkaline phosphataseFourier transform infrared spectroscopyChemistryMaterials scienceScanning electron microscopeBiocompatibilityOsteoblastBiomaterialBioactive glassPolyvinyl alcoholBone tissueChitosanBone regenerationSol-gelChemical engineeringTissue engineeringPolymerPorosity
96Publications
24H-index
2,661Citations
Publications 93
Newest
#1Andréia Grossi Santos de Laia (UFMG: Universidade Federal de Minas Gerais)H-Index: 2
#2Thalita M. Valverde (UFMG: Universidade Federal de Minas Gerais)H-Index: 5
Last. Marivalda M. Pereira (UFMG: Universidade Federal de Minas Gerais)H-Index: 24
view all 10 authors...
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#1Layla Mosqueira (UFMG: Universidade Federal de Minas Gerais)
#2Breno Rocha Barrioni (UFMG: Universidade Federal de Minas Gerais)H-Index: 6
Last. Marivalda M. Pereira (UFMG: Universidade Federal de Minas Gerais)H-Index: 24
view all 6 authors...
Osteoporosis is a metabolic disease that affects bone tissue and is highly associated with bone fractures. Typical osteoporosis fracture treatments, such as bisphosphonates and hormone replacement, present important challenges because of their low bioavailability on the site of action. Options to overcome this issue are systems for the local release of therapeutic agents such as bioactive glasses containing therapeutic molecules and ions. These agents are released during the dissolution process,...
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#1Andréia Grossi Santos de Laia (UFMG: Universidade Federal de Minas Gerais)H-Index: 2
#2Breno Rocha Barrioni (UFMG: Universidade Federal de Minas Gerais)H-Index: 6
Last. Marivalda M. Pereira (UFMG: Universidade Federal de Minas Gerais)H-Index: 24
view all 6 authors...
Hybrid scaffolds appear as a promising strategy to accelerate bone tissue repair due to their biocompatibility and to combine physical, mechanical and biological characteristics similar to those of human bone tissue. However, there are no studies in hybrid scaffolds using the sol–gel method and a foaming system, with the direct incorporation of cobalt therapeutic ion. In this work, novel porous polyvinyl alcohol polymer (PVA)/bioactive glasses (BG) hybrids scaffolds containing cobalt were obtain...
4 CitationsSource
#1Ingrid Elen Pinto e Souza (UFMG: Universidade Federal de Minas Gerais)
#2Sandhra M. Carvalho (UFMG: Universidade Federal de Minas Gerais)H-Index: 18
Last. Marivalda M. Pereira (UFMG: Universidade Federal de Minas Gerais)H-Index: 24
view all 4 authors...
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#1Diogo M. M. dos Santos (UFMG: Universidade Federal de Minas Gerais)H-Index: 2
#2Talita Martins (UFMG: Universidade Federal de Minas Gerais)H-Index: 3
Last. Eduardo H.M. Nunes (UFMG: Universidade Federal de Minas Gerais)H-Index: 15
view all 6 authors...
Abstract Composite scaffolds were successfully obtained using sol-gel derived 58S bioactive glass particles and poly(e-caprolactone) pellets. Camphene was used as the freezing vehicle. No sintering step was used, which represents a great advantage in terms of energy and time-saving. The prepared scaffolds showed a mechanical behavior similar to elastomeric cellular solids and Young’s modulus of 46.7 ± 9.4 MPa, which may allow their use in load-bearing applications. Cytotoxicity tests revealed th...
3 CitationsSource
#1Endrigo Gabellini Leonel Alves (UFMG: Universidade Federal de Minas Gerais)H-Index: 6
#2Rogéria Serakides (UFMG: Universidade Federal de Minas Gerais)H-Index: 19
Last. C.M.F. Rezende (UFMG: Universidade Federal de Minas Gerais)H-Index: 2
view all 8 authors...
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#1Breno Rocha Barrioni (UFMG: Universidade Federal de Minas Gerais)H-Index: 6
#2Elizabeth Norris (Imperial College London)H-Index: 4
Last. Marivalda M. Pereira (UFMG: Universidade Federal de Minas Gerais)H-Index: 24
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Bioactive glasses (BGs) are widely used for bone regeneration, and allow the incorporation of different ions with therapeutic properties into the glass network. Amongst the different ions with therapeutic benefits, manganese (Mn) has been shown to influence bone metabolism and activate human osteoblasts integrins, improving cell adhesion, proliferation and spreading. Mn has also been incorporated into bioceramics as a therapeutic ion for improved osteogenesis. Here, up to 4.4 mol% MnO was substi...
7 CitationsSource
#1Cheisy D.F. Moreira (UFMG: Universidade Federal de Minas Gerais)H-Index: 3
#2Sandhra M. Carvalho (UFMG: Universidade Federal de Minas Gerais)H-Index: 18
Last. Marivalda M. Pereira (UFMG: Universidade Federal de Minas Gerais)H-Index: 24
view all 8 authors...
Abstract The present work describes in vitro and in vivo behaviors of thermosensitive composite hydrogels based on polymers/bioactive glass nanoparticles. Assays in SBF (simulated body fluid) solution showed that loss of hydrogel mass in vitro was decreased by 4.3% when bioactive glass nanoparticles (nBG) were incorporated, and confirmed the bioactivity of nBG containing hydrogels. In vitro assays demonstrated the cytocompatibility of the hydrogels with encapsulated rat bone marrow mesenchymal s...
10 CitationsSource
#1Breno Rocha Barrioni (UFMG: Universidade Federal de Minas Gerais)H-Index: 6
#2Parichart Naruphontjirakul (Imperial College London)H-Index: 6
Last. Marivalda M. Pereira (UFMG: Universidade Federal de Minas Gerais)H-Index: 24
view all 9 authors...
Abstract Bioactive glass nanoparticles (BGNPs) are of great interest in tissue engineering as they possess high dissolution rate and capability of being internalized by cells, releasing their dissolution products with therapeutic benefits intracellularly. A modified Stober process can be applied to obtain different BGNPs compositions containing therapeutic ions while maintaining controllable particle morphology, monodispersity and reduce agglomeration. Here, BGNPs containing Mn, an ion that has ...
14 CitationsSource
#1Diogo M. M. dos Santos (UFMG: Universidade Federal de Minas Gerais)H-Index: 2
#2Sandhra M. Carvalho (UFMG: Universidade Federal de Minas Gerais)H-Index: 18
Last. Eduardo H.M. Nunes (UFMG: Universidade Federal de Minas Gerais)H-Index: 15
view all 5 authors...
Abstract This work deals with the preparation of freeze-cast scaffolds using sol-gel derived 58S bioactive glass and a hypoeutectic naphthalene-camphor mixture as the starting powder and freezing vehicle, respectively. After the freeze-casting step, samples were air sintered at 1250 °C for 2 h, which led to the crystallization of 58S. The obtained scaffolds were subsequently infiltrated with poly(e-caprolactone) (PCL), a biodegradable polymer with potential application for bone tissue repair. Th...
6 CitationsSource
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