Jingbo Yin
Shanghai University
Self-healing hydrogelsPolyelectrolyteComposite materialRegeneration (biology)ChemistryPolymer chemistryMaterials scienceCrystallizationIn vivoBiocompatibilityChitosanPLGACartilageChondrogenesisChemical engineeringTissue engineeringPolymerPorosityScaffoldNanocomposite
81Publications
24H-index
1,784Citations
Publications 70
Newest
#1Zhen Shi (SHU: Shanghai University)H-Index: 1
#2Qi Wang (SHU: Shanghai University)H-Index: 1
Last. Jingbo Yin (SHU: Shanghai University)H-Index: 24
view all 8 authors...
Self-healing hydrogels with the shear-thinning property are novel injectable materials and are superior to traditional injectable hydrogels. The self-healing hydrogels based on 2-ureido-4[1H]-pyrimidinone (UPy) have recently received extensive attention due to their dynamic reversibility of UPy dimerization. However, generally, UPy-based self-healing hydrogels exhibit poor stability, cannot degrade in vivo and can hardly be excreted from the body, which considerably limit their bio-application. ...
1 CitationsSource
#1Pengfei Xia (SHU: Shanghai University)H-Index: 3
#2Kunxi Zhang (SHU: Shanghai University)H-Index: 14
Last. Jingbo Yin (SHU: Shanghai University)H-Index: 24
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Abstract Developing microtissues that could promote bone regeneration remains a challenge. This study develops a biomimetic, biodegradable and osteoinductive microgel called 40% strontium-substituted hydroxyapatite/Microgel (40% Sr-HA/Microgel) to construct microtissues that could facilitate bone tissue regeneration. The open porous structure (with a pore diameter of 33 μm and porosity of 88%) of the 40% Sr-HA/Microgels could promote cellular proliferation and realize cell-cell interactions. The...
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#1Xi Yu (SHU: Shanghai University)H-Index: 1
#2Yihui Hu (SJTU: Shanghai Jiao Tong University)H-Index: 4
Last. Jingbo Yin (SHU: Shanghai University)H-Index: 24
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Abstract Temporomandibular joint (TMJ) supports chewing, talking or other daily oral activities. So far, it still remains a great challenge to treat the defected TMJ condyle cartilage through tissue engineering technology. Herein, a bilayered scaffold is designed to fully reconstruct the different cartilage matrices of TMJ condyle under same induction condition. The bilayered scaffold with segregated hydrophobicity-hydrophilicity in top and bottom layer is prepared from a low and high content of...
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#1Zijie Xiahou (SHU: Shanghai University)
#2Yunlang She (Tongji University)
Last. Jingbo Yin (SHU: Shanghai University)H-Index: 24
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Stem-cell-derived organoid can resemble in vivo tissue counterpart and mimic at least one function of tissue or organ, possessing great potential for biomedical application. The present study devel...
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#1Hong-Jie Zong (SHU: Shanghai University)H-Index: 1
#2Bo Wang (SHU: Shanghai University)H-Index: 2
Last. Jingbo Yin (SHU: Shanghai University)H-Index: 24
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Currently, biodegradable hydrogels are one of the most promising materials in tissue engineering. From the perspective of clinical needs, hydrogels with high strength and minimally invasive implant...
4 CitationsSource
#1Yufeng Shou (SHU: Shanghai University)H-Index: 3
#2Jiahui Zhang (SHU: Shanghai University)H-Index: 1
Last. Jingbo Yin (SHU: Shanghai University)H-Index: 24
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Chitosan (CS) hydrogels are widely used in wound hemostatic agents due to their superior biocompatibility, biodegradability, and hemostatic effect. However, most of them fail to achieve great hemos...
8 CitationsSource
#1Yechi Qin (SHU: Shanghai University)H-Index: 2
#2Guifei Li (SHU: Shanghai University)H-Index: 9
Last. Jingbo Yin (SHU: Shanghai University)H-Index: 24
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Towards osteochondral tissue construction, the present study introduced a bilayer scaffold to induce sequential chondrogenesis and osteogenesis of stem cells in vitro. Two scaffolds that both based...
2 CitationsSource
#1Bu Shuai (SHU: Shanghai University)H-Index: 1
#2Shifeng Yan (SHU: Shanghai University)H-Index: 22
Last. Jingbo Yin (SHU: Shanghai University)H-Index: 24
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Bone tissue engineering scaffold based on microcarriers provides an effective approach for the repair of irregular bone defects. The implantation of microcarriers by injection can reduce surgical trauma and fill various irregular shaped bone defects. Microcarriers with porous structure and osteogenic properties have shown great potential in promoting the repair of bone defects. In this study, two kinds of hydroxyapatite/poly-(γ-benzyl-l-glutamate) (HA/PBLG) microcarriers were constructed by emul...
3 CitationsSource
#1Yuhao Hong (SHU: Shanghai University)H-Index: 1
#2Jialin Chen (SJTU: Shanghai Jiao Tong University)H-Index: 1
Last. Jingbo Yin (SHU: Shanghai University)H-Index: 24
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Adipose derived stem cell (ASC) spheroids exhibit enhanced angiogenic efficacy towards ischemia treatment. Thus, it is necessary to develop an all-in-one platforms enabling efficient spheroids production, collection and injectable implantation in vivo. The present study fabricated a poly (L-glutamic acid) (PLGA) based porous hydrogel that could not only produce ASC spheroids, but also conveniently collect spheroids for in vivo implantation via minimally invasive injection to treat hind limb isch...
2 CitationsSource
#1Qi Wang (SHU: Shanghai University)H-Index: 1
#2Zhen Shi (SHU: Shanghai University)H-Index: 1
Last. Jingbo Yin (SHU: Shanghai University)H-Index: 24
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Supramolecular hydrogels formed by non-covalent bonds are attractive ‘smart’ materials, which can rapidly respond to external stimuli. However, only a handful of supramolecular hydrogels are applicable in tissue engineering, due to the instability and poor-performed mechanical strength of non-covalent crosslinking hydrogels. Thus, a rigid and stable supramolecular hydrogel has been developed based on poly(L-glutamic acid) (PLGA) and 2-ureido-4[1H]pyrimidinones (UPy), and the UPy stacks are non-c...
4 CitationsSource